SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Presentations I |
| Discussion Leader: Marcelo Jacobs-Lorena (Johns Hopkins School of Public Health) |
7:40 pm - 8:20 pm | Regina Rabinovich (Gates Foundation)
"Research with the end in mind - how the disease control agenda raises the challenge for research" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Judd Walson (University of Washington, Seattle)
"Divided we fall; leveraging the opportunity of the HIV/AIDS response for other tropical infectious diseases" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Cholera |
| Discussion Leader: Matthew Waldor (Harvard University) |
9:00 am - 9:20 am | Matthew Waldor (Harvard University)
"Vibrio cholerae physiology during infection" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Steve Calderwood (Massachusetts General Hospital)
"Immunological memory and protection from Vibrio cholerae" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Gary Schoolnik (Stanford University)
"V. cholerae: bistable switches that control virulence gene expression and competence" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Andrew Camilli (Tufts University)
"New insight into transmission of cholera" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | John Mekalanos (Harvard University)
"Cholera emergence and epidemic ecology" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Selected poster (TBA) |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Selected poster (TBA) |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Rickettsia |
| Discussion Leader: Abdu Azad (University of Maryland) |
7:30 pm - 7:50 pm | Ulrike Munderloh (University of Minnesota)
"Are we there yet? Genetic Manipulation of vector-borne rickettsial agents" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Yasuko Rikihisa (Ohio State University)
"A microbial strategy to multiply in phagocytes" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Daniel Voth (University of Arkansas)
"The Coxiella burnetii cryptic plasmid: a treasure trove of type IV effector proteins" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Selected poster (TBA) |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Selected poster (TBA) |
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Leishmania |
| Discussion Leader: David Sacks (National Institute of Allergy and Infectious Diseases) |
9:00 am - 9:20 am | David Sacks (NIAID)
"The Cell Biology of Leishmania - Sand Fly Interactions" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Nicolas Fasel (Université de Lausanne, Switzerland)
"Virulence in mucocutaneous leishmaniasis" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Lynn Soong (University of Texas, Galveston)
"Subversion and modulation of host immunity by Leishmania parasites" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Alan Magill (Defense Advanced Research Projects Agency, USA)
"Leishmaniasis: the top 10 needs from the field" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Alain Dessein (Université de la Méditerranée, France)
"Alterations in immune defenses that aggravate visceral and cutaneous leihmaniasis in endemic populations" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Selected poster (TBA) |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Selected poster (TBA) |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | African trypanosomiasis |
| Discussion Leader: Serap Aksoy (Yale University) |
7:30 pm - 7:50 pm | Serap Aksoy (Yale University)
"Novel insights into trypanosome development in tsetse" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Jayne Raper (NYU Langone Medical Center)
"Mechanisms Underlying Species Specific Trypanosome Resistance - Bench to African Smallholder Farmer" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Enock Matovu (Makere University, Uganda)
"Continued spread of Trypanosoma brucei rhodesiense into northern Uganda: a looming calamity" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Selected poster (TBA) |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Selected poster (TBA) |
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Arboviruses |
| Discussion Leader: Scott Weaver (University of Texas, Galveston) |
9:00 am - 9:20 am | Scott Weaver (University of Texas, Galveston)
"Dengue and chikungunya: history and evolution of urban emergence" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | George Dimopoulos (Johns Hopkins University)
"Delicate tripartite interactions determine vectorial competence of mosquitoes" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Julia Brown (Yale University)
"Population genetic studies of human association and vector competence for dengue in Aedes aegypti" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Stephen Whitehead (NIH)
"Clinical evaluation of the NIH live attenuated dengue vaccine" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Amy Morrison (University of California, Davis)
"Lessons learned from prospective cohort studies of dengue virus transmission in Iquitos, Peru: Implications for vector and vaccine control strategies" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Selected poster (TBA) |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Selected poster (TBA) |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Filariasis |
| Discussion Leader: Thomas Nutman (NIH) |
7:30 pm - 7:50 pm | Elodie Ghedin (Pittsburgh School of Medicine)
"Mapping host-parasite interactions of Brugia malayi and its Wolbachia endosymbiont" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Sara Lustigman (New York Blood Center)
"The development of a recombinant vaccine against human onchocerciasis" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Thomas Nutman (NIH)
"Regulatory networks induced by filarial infections: bystander effects modulate outcomes in other infectious diseases at both the bedside and the bench" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Selected poster (TBA) |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Selected poster (TBA) |
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Malaria |
| Discussion Leader: Ricardo Gazzinelli (Fiocruz, Brazil & University of. Massachusetts) |
9:00 am - 9:20 am | Brendan Crabb (Burnet Institute, Australia)
"Protein export is an Achille's heel in malaria parasite development and virulence" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Ricardo Gazzinelli (Fiocruz, Brazil & University of. Massachusetts)
"Pyroptosis in malaria: checkpoints for in vivo activation of inflammasome and IL-1 beta release" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | David Fidock (Columbia University)
"PfCRT: new insights into its contribution to chloroquine resistance and impact on P. falciparum transmission and fitness" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Xin-zhuan Su (NIH)
"Identification of antimalarial agents and their genetic targets using high-throughput chemical screening and genome-wide mapping" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Jim Kazura (Case Western Reserve University)
"Naturally Acquired immunity to Plasmodium falciparum: age and exposure dependent determinants" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Selected poster (TBA) |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Selected poster (TBA) |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote Presentations II |
| Discussion Leader: TBA |
7:30 pm - 8:10 pm | Alan Cowman (The Walter and Eliza Hall Institute of Medical Research, Australia)
"Moving house: invasion and remodelling of the host erythrocyte by P. falciparum" |
8:10 pm - 8:30 pm | Discussion |
8:30 pm - 9:10 pm | Adel Mahmoud (Princeton University)
"Perspectives on vaccine discovery and development" |
9:10 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |