Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Bacterial-Host Interactions in Symbiosis and Disease
Discussion Leader: Jesus Valenzuela (National Institute of Allergy and Infectious Diseases, NIH, USA)
7:40 pm - 8:20 pm
Alan Sher (National Institutes of Health, USA)
"New Immunologic Targets for the Prevention and Treatment of Tuberculosis"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
George Dimopoulos (Johns Hopkins Bloomberg School of Public Health, USA)
"Exploring the Mosquito-Microbiota for Disease Control"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
Yasmine Belkaid (National Institute of Allergy and Infectious Diseases, NIH, USA)
"Microbiota Control of Tissue Immunity and Repair"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Bacterial Infections and Antibiotic Resistance
Discussion Leader: Yasmine Belkaid (National Institute of Allergy and Infectious Diseases, NIH, USA)
9:00 am - 9:20 am
David Weiss (Emory Antibiotic Resistance Center, USA)
"Undetected Antibiotic Resistance Leading to Treatment Failure"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Iris Cazali (Hospital Roosevelt, Guatemala)
"A Klebsiella Outbreak in a Reference Low-Income University Hospital in Guatemala City"
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
Dario Zamboni (Faculdade de Medicina de Ribeirão Preto, University of São Paulo, Brazil)
"Inflammasomes in Host Response to Intracellular Bacteria"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Joe Hinnebusch (National Institute of Allergy and Infectious Diseases, NIH, USA)
"Comparative Evaluation of Two Modes of Flea-Borne Plague Transmission: Implications for Disease Outcome and Ecology"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
Katrin Mayer-Barber (National Institutes of Health, USA)
"Pulmonary Innate Immune Responses to Mycobacterium tuberculosis "
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
Eachan Johnson (Broad Institute of MIT and Harvard, USA)
"Large-Scale Chemical-Genetics Yields New Classes of Inhibitors of Mycobacterium tuberculosis "
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
William Jacobs (Albert Einstein College of Medicine, USA)
"Pursuing Edward Jenner's Revenge"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
Organizers: Maria Elena Bottazzi (Baylor College of Medicine, USA), Shaden Kamhawi (National Institute of Allergy and Infectious Diseases, NIH, USA) and Jesus Valenzuela (National Institute of Allergy and Infectious Diseases, NIH, USA)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Vector Biology and Disease Transmission
Discussion Leaders: Alvaro Molina-Cruz (National Institute of Allergy and Infectious Diseases, NIH, USA) and Saravanan Thangamani (SUNY Upstate Medical University, USA)
7:30 pm - 7:50 pm
Nora Besansky (University of Notre Dame, USA)
"Malaria Vector Analysis and Chromosomal Inversions"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Joel Vega-Rodriguez (National Institutes of Health, USA)
"Malaria Transmission Requires Interaction with the Mammalian Fibrinolytic Proteins"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Abdoulaye Diabate (Institute de Recherche en Sciences de la Sante (IRSS) / Centre Muraz, Burkina Faso)
"Gene Drive and Malaria Control: What Does It Take to Get to the Field?"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Hilary Ranson (Liverpool School of Tropical Medicine, United Kingdom)
"Can Adoption of 'Next Generation' Bednets Stem the Resurgence of Malaria in Africa?"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Disrupting Mosquito-Borne Disease Transmission
Discussion Leaders: Nora Besansky (University of Notre Dame, USA) and Joel Vega-Rodriguez (National Institutes of Health, USA)
9:00 am - 9:20 am
Rebeca Carballar-Lejarazu (University of California, Irvine, USA)
"Mosquito Population Modification and the Malaria Eradication Agenda"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Stephanie James (Foundation for the National Institutes of Health, USA)
"A Roadmap for Responsible Research on Gene Drive Technology for Malaria Control"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Marcelo Jacobs-Lorena (Johns Hopkins Bloomberg School of Public Health, USA)
"Reversible Paratransgenesis"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Flaminia Catteruccia (Harvard T.H. Chan School of Public Health, USA)
"Targeting Malaria Parasites Within the Anopheles Female"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Gaspar Canepa (National Insitutes of Health, USA)
"Development of a Pfs47-Based Vaccine to Disrupt Plasmodium falciparum Transmission: Recent Advances"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Camila Coelho (National Institute of Allergy and Infectious Diseases, NIH, USA)
"A Human Anti-Plasmodium falciparum Pfs230 Monoclonal Antibody Greatly Reduces Malaria Transmission"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Luciano Moreira (Instituto René Rachou, Fiocruz Minas, Brazil)
"Breaking Paradigms: Using Mosquitoes to Control Arboviruses!"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Biology and Control of Trypanosomiasis and Filariasis
Discussion Leader: Boris Striepen (University of Pennsylvania, USA)
7:30 pm - 8:00 pm
Serap Aksoy (Yale University School of Medicine, USA)
"New Insights in Trypanosome Transmission in the Tsetse Vector"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
Monica Mugnier (Johns Hopkins Bloomberg School of Public Health, USA)
"Trypanosoma brucei Antigenic Variation in the Extravascular Niche"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
Santuza Teixeira (Federal University of Minas Gerais, Brazil)
"Gene Expression Control During the Life Cycle of Trypanosoma cruzi "
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Emerging Arboviruses: Vectors, Virulence and Transmission
Discussion Leaders: George Dimopoulos (Johns Hopkins Bloomberg School of Public Health, USA) and Jose Ramirez (U.S. Department of Agriculture, USA)
9:00 am - 9:20 am
Raul Andino (University of California, San Francisco, USA)
"Antiviral Adaptive Immunity in Insects"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Ann Powers (Centers for Disease Control and Prevention, USA)
"Searching for Re-Emerging, Endemic Arboviruses in Indonesia"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Katherine Glass (London School of Hygiene and Tropical Medicine, United Kingdom)
"Multiplex, High-Throughput Arrays to Profile Seroreactivity to Vaccine and Pathogen Antigens"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Joao Marques (Universidade Federal de Minas Gerais, Brazil)
"A Unique Specialization of Antiviral RNA Interference in Aedes Mosquitoes"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
Pei-Yong Shi (University of Texas Medical Branch, USA)
"A Single-Dose DNA-Launched Live-Attenuated Zika Vaccine"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
Garrett League (Cornell University, USA)
"Sex, Seminal Fluids and Swarms: Determinants of Harmonic Convergence in Aedes aegypti and Anopheles gambiae Mosquitoes"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Scott Weaver (University of Texas Medical Branch, USA)
"Mechanisms of Urban Arbovirus Emergence"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Infection Genomics, Proteomics and Metabolomics
Discussion Leader: Raul Andino (University of California, San Francisco, USA)
7:30 pm - 7:50 pm
Rushika Perera (Colorado State University, USA)
"Exploiting Mosquito Metabolism for Prevention of Human Arboviral Transmission"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Robert Waterhouse (University of Lausanne / Swiss Institute of Bioinformatics, Switzerland)
"Harnessing Evolution to Inform Function in Disease-Vector Biology"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Peter Crompton (National Institute of Allergy and Infectious Diseases, NIH, USA)
"A Molecular Signature in Blood Reveals a Role for P53 in Malaria Immunity in Children"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Christopher Sassetti (University of Massachusetts, USA)
"Determinants of Antibiotic Efficacy During M. tuberculosis Infection"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Advances in Understanding the Biology of Protozoan Parasites
Discussion Leaders: Shaden Kamhawi (National Institute of Allergy and Infectious Diseases, NIH, USA) and Lynn Soong (The University of Texas Medical Branch, USA)
9:00 am - 9:20 am
Claudia Brodskyn (Instituto Gonçalo Moniz, Fiocruz, Brazil)
"Immune Response to Sand Fly Saliva as a Biomarker of Vector Exposure in an Endemic Area for Canine Visceral Leishmaniasis"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Alejandro Antonia (Duke University, USA)
"Leishmania Encoded Evasion of Chemokine Signaling and T-Cell Response"
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
Silvia Portugal (Heidelberg University Hospital, Germany)
"Plasmodium falciparum Dry Season Reservoir"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Igor Almeida (University of Texas at El Paso, USA)
"Early Assessment of Therapeutic Outcomes in Experimental and Clinical Chagas Disease"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
Ana Rodriguez (New York University School of Medicine, USA)
"Autoimmunity as a Cause for Anemia in Malaria"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
Camila De Oliveira (Fundação Oswaldo Cruz, Brazil)
"Antibody Response to Linb-13 as a Marker of Severity Across the Tegumentary Leishmaniasis Clinical Spectrum"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Boris Striepen (University of Pennsylvania, USA)
"Cryptosporidium Host-Parasite Interaction"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Keynote Session: Breakthroughs in Parasite Biology
Discussion Leader: Fabiano Oliveira (National Institutes of Health, USA)
7:30 pm - 8:10 pm
Stephen Beverley (Washington University in St. Louis, USA)
"Origins and Contributions of Protozoal Viruses to Parasite Virulence"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
Maria Mota (Instituto de Medicina Molecular João Lobo Antunes, Portugal)
"Host, Plasmodium and the Surrounding Environment"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Jesus Valenzuela (National Institute of Allergy and Infectious Diseases, NIH, USA)
"A New Stage of Leishmania in the Sand Fly Gut and Its Role in Transmission"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure