Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Frugal Science
Discussion Leader: Ana Beatriz Barletta Ferreira (National Institutes of Health, USA)
3:45 pm - 4:15 pm
Manu Prakash (Stanford University, USA)
"Frugal Science"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Complex Interactions: The Interplay Between Vector, Pathogen, Host and the Microbiome
Discussion Leaders: Brandon Trent (University of Texas Medical Branch, USA) and Thiago Silva (National Institutes of Health, USA)
7:30 pm - 7:40 pm
Anubama Rajan (Baylor College of Medicine, USA)
"Next-Gen Models of Infection: How Human Intestinal Enteroids Challenge Current Paradigms of Bacterial Adherence"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Alejandro Antonia (Duke University, USA)
"Pathogen Encoded Evasion of CXCL10 and T-Cell Responses"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Iliano Coutinho-Abreu (National Institutes of Health, USA)
"Transcriptional Plasticity of Leishmania Developmental Stages in the Vector"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Joshua Lacsina (National Institute of Allergy and Infectious Diseases, NIH, USA)
"The BITE Study: Defining Human Skin Immunity to Vector Insect Bites"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Christopher Roundy (University of Texas Medical Branch, USA)
"Effects of Colonization on the Aedes aegypti Microbiome and Vector Competence"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Gianmarco Raddi (National Institute of Allergy and Infectious Diseases, NIH, USA)
"Cellular Immunity Against Malaria: An Atlas of Mosquito Hemocytes at Single Cell Resolution"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Camila Coelho (National Institute of Allergy and Infectious Diseases, NIH, USA)
"The Immunological Interplay Between Giardia duodenalis and Toxoplasma gondii During Murine Co-Infection"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Liu Yang (Yale University, USA)
"Paratransgenic Manipulation of microRNA275 in Tsetse Fly and the Downstream Effect on Trypanosome Infection"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Basic and Translational Insights into Neglected Tropical Diseases
Discussion Leaders: Von Ralph Dane Herbuela (Ehime University, Japan) and Emma Camacho (Johns Hopkins University, USA)
9:00 am - 9:10 am
Susana Portillo (University of Texas at El Paso, USA)
"A Prophylactic a-Gal-Based Glycovaccine Effectively Protects Against Murine Acute Chagas Disease"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Claudia Calvet Alvarez (University of California, San Diego, USA)
"New Treatments to Ameliorate Heart Fibrosis During Chagas Disease Cardiomyopathy"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Rebecca Byler (Yale University, USA)
"Rational Development of a Target Product Profile for Designing Multifunctional, Topical Therapeutics for Cutaneous Leishmaniasis in Colombia"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Shuhei Taguwa (Stanford University, USA)
"Dependences of Zika Virus on Host Hsp70s Provide Novel Protective Strategy Against Flavivirus Infection and Disease"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Judith Weber (University of Bremen, Germany)
" Trypanosomes, Tsetse Flies and Their Bacteria in Nigeria and Cameroon: Sialidases from Gut Bacteria as Potential Targets to Prevent Trypanosoma Colonization in Tsetse"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Octavio Augusto Talyuli da Cunha (Universidade Federal do Rio de Janeiro, Brazil)
"HPx1: A Heme-Induced Peroxidase of the Peritrophic Matrix that Shapes Antioxidant and Immune Function in Aedes aegypti "
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Emily Mathews (Washington University in St. Louis, USA)
"The Role of Heat Shock Protein Prenylation in Plasmodium falciparum "
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Maria Luisa Simoes (Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, USA)
"CRISPR/Cas9 Gene Editing to Block Malaria Transmission"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Your Career Path and Tropical Infectious Diseases
Discussion Leaders: Angela Kruse (Cornell University, USA) and Mabel Taracena (CDC Foundation, USA)
1:30 pm - 2:30 pm
Panel Discussion
Your Career Path and Tropical Infectious Diseases
Michael Dilling (Baylor College of Medicine, USA)
Sean Ekins (Collaborations Pharmaceuticals, Inc., USA)
Carolyn Wilson (U.S. Food and Drug Administration, USA)
Manu Prakash (Stanford University, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
