Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Challenges for Global Vaccines and Vaccinations
Discussion Leader: Pedro Gazzinelli-Guimaraes (NIAID-NIH, United States)
3:45 pm - 4:25 pm
Peter Hotez (Baylor College of Medicine, United States)
"Global Vaccines and Vaccinations: the Science Versus the Antiscience"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Basic and Translational Research in Tropical Infectious Diseases
Discussion Leader: Leroy Versteeg (Baylor College of Medicine, United States)
7:30 pm - 7:40 pm
Lauren Bambarger (The Johns Hopkins University, United States)
"Progress Towards Targeting and Probing the Unique and Dynamic Activity of DXP Synthase, a Novel Anti-Infective Drug Target"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Richardson Kwesi Egyirifa (Noguchi Memorial Institute for Medical Research, University of Ghana, Ghana)
"Mosquito Microbiome: A Key for Malaria Transmission Blocking Strategies."
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Sazzad Mahmood (NIAID, NIH, United States)
"The “Sialome Switch” of Lxodes Scapularis at the Single-Cell Resolution"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Pollyanna Gomes (Fiocruz, Brazil)
"Subtilisin of Leishmania amazonensis as Potential Druggable Target: Subcellular Localization, In Vitro Leishmanicidal Activity and Molecular Docking of PF-429242, a Subtilisin Inhibitor"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Ana Leao (Baylor College of Medicine, United States)
"Characterization of Vaccine-Linked Chemotherapy Induced B Cell Responses in Chronic Trypanosoma Cruzi Infection"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Camilo Espinosa Bernal (Stanford School of Medicine, United States)
"Multiomics Characterization of Infant Acute Illness and Post-Discharge Mortality in Low- and Middle-Income Countries"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Pedro Amado Cecilio (National Institute of Allergy and Infectious Diseases, NIH, United States)
"Are the Bites of Non-Infected Sand Flies Important for the Maintenance of Animal Reservoirs of Cutaneous Leishmaniasis?"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Vivian Tat (The University of Texas Medical Branch, United States)
"Characterizing Spatial and Temporal Host Innate Immune Responses to SARS-CoV-1 and -2 Infection in Pathologically Relevant Human Lung Epithelial Cells"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Pathogen-Host-Vector Tripartite Interactions
Discussion Leaders: Stephen Lu (NIAID-NIH, United States) and Anushka Saha (Georgia Institute of Technology, United States)
9:00 am - 9:10 am
Emma Camacho (Johns Hopkins University, United States)
"Boosting Anopheles Gambiae Melanization, a Potential Strategy for Malaria Control"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Shreyoshi Chakraborti (Stony Brook University, United States)
"MelH Acts as an Oxidative Stress Regulator that Alters Fatty Acid and Lipid Biosynthesis and is Essential for Virulence of Mycobacterium Tuberculosis"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Laura Willen (National Institute of Allergy and Infectious Diseases, NIH, United States)
"New Biomarkers of Aedes Exposure and their Association with Dengue Disease Status: a Longitudinal Dengue Cohort in Cambodia"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Maria Diaz de Leon Derby (University of California Berkeley, United States)
"Mobile Phone-based Diagnostics for Neglected Tropical Diseases: Automated Identification of Schistosoma haematobium from Urine Samples"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Priscila S G Farani (University of Texas at El Paso, United States)
"Prophylactic Glycan- and Peptide-Based Vaccines Elicit a Protective Immune Response, miRNA Differential Expression, and Metabolomic Modulation in a Nonhuman Primate Model of Chagas Disease"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Nourou Barry (IRSS/UNB, Burkina Faso)
"A multi-disciplinary approach for building a common understanding of genetic engineering for malaria control in Burkina Faso"
10:25 am - 10:30 am
Discussion
10:30 am - 10:45 am
General Discussion
10:45 am - 10:55 am
Divya Shinde (University of Texas Medical Branch, United States)
"Effect of Pre-Existing Zika Immunity on Yellow Fever Virus Infection"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Traditional and Non-Traditional Career Options in Tropical Infectious Diseases
Discussion Leader: Lucas Tirloni (National Institute of Allergy and Infectious Diseases (NIAID), United States)
1:30 pm - 2:30 pm
Panel Discussion
Schistosomiasis Vaccine Development Partnership Program
Caeul Lim (Frederick National Lab, United States)
Mary Catherine Longshore (AAAS, United States)
Filipa Rijo-Ferreira (University of California, Berkeley , United States)
Oliver Prince (MilliporeSigma, United States)
Omar Harb (University of Pennsylvania (VEuPathDB.org), United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes