Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: Probes of the Mycobacterial Cell Envelope
Discussion Leaders: Maral Budak (University of Michigan, United States) and Anna Upton (Evotec, United States)
3:15 pm - 3:50 pm
Laura Kiessling (Massachusetts Institute of Technology, United States)
"Probes of the Mycobacterial Cell Envelope"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
TB Innovation: Drug and Vaccine Development
Discussion Leaders: Kelly Chibale (University of Cape Town, South Africa) and Vinay Barnabas (Indian Institute of Technology Bombay, India)
5:30 pm - 5:45 pm
Erin Wang (Washington University School of Medicine, United States)
"Metabolic Determinants of Isoniazid Susceptibility in Mycobacterium Tuberculosis "
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Laura Boardman-Slack (The University of Lincoln, United Kingdom)
"Evaluating a New Isocitrate Lyase Inhibitor as a Potential Anti-Tubercular Compound"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
ESMERALDA REYES-FERNANDEZ (ALBERT EINSTEIN COLLEGE OF MEDICINE, United States)
"The Role of Chorismate Mutase in Mycobacterium Tuberculosis Pathogenesis"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Rachel Rollo (Frazer Institute, The University of Queensland, Australia)
"Characterization of the Anti-Mycobacterial Activity of Wollamide Cyclic Hexapeptides"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
GOURAV RAKSHIT (Birla Institute of Technology, Mesra, Ranchi, INDIA, India)
"Non-Nucleoside Mycobactin Analogues: Prospective Therapeutic Candidates to Tackle AMR in TB"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Laura Cioetto Mazzabò (Department of Molecular Medicine, Padova 35121, Italy)
"Smart Prodrugs Able to Produce Their Own Activation"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Highlights in Mycobacterial Physiology and Pathogenicity
Discussion Leaders: Tania Lupoli (New York University, United States) and Akanksha . (Indian Institute of Technology Bombay, India)
9:00 am - 9:15 am
Ruby Froom (Rockefeller University, United States)
"Cell-Free Genomics Reveals Novel Regulatory Sites in the Mycobacterium Tuberculosis Genome"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Charlie Pyle (Duke University, United States)
"EMP2 is the Foundation of Mycobacterial Granuloma Cellular Infrastructure"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Tejan Lodhiya (IISER Tirupati, India, India)
"Understanding the Complex Secondary Mechanisms Involved in Mycobacterial Cell Death"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Joshua Brewer (Rockefeller University, United States)
"Structural Basis of Promoter Escape in Mycobacterium Tuberculosis "
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Greta Segafreddo (University of Padova, Italy)
"Insights on the Role and Regulation of M. Tuberculosis Sigma Factor C"
10:35 am - 10:40 am
Discussion
10:40 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Diversity and Mentorship in a Changing Landscape
Discussion Leader: Dirk Schnappinger (Weill Cornell Medical College, United States)
1:30 pm - 2:30 pm
Panel Discussion
Diversity and Mentorship in a Changing Landscape
Kelly Chibale (University of Cape Town, South Africa)
Tania Lupoli (New York University, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes