Sunday, July 2 7:30-9:30pm | Vascular Biology & Vessel Patterning |
- Chair: Celeste Simon, Abramson Family Cancer Research Institute
"bHLH-PAS Proteins, Hypoxia & Vascular Development"
- Mark Fishman, Massachusetts General Hospital
"Genetic Dissection of Vessel Patterning in Zebrafish"
- Harold Dvorak, Beth Israel Deaconess Medical Center
" Heterogeneity of the Angiogenic Response Induced by VPF/VEGF"
- Brian Helmke, University of Pennsylvania, Short Presentation
"Shear stress-induced cytoskeletal displacement in living endothelial cells"
Monday, July 3 9:00am-12:30pm | Vascular Development |
- Chair: Charles Little, Medical University of South Carolina
"Endothelial Cells Behavior During Formation of the Primary Vasculature"
- Kari Alitalo, University of Helsinki
"Regulating VEGFs Angiogenesis Verses Lymphangiogenesis"
10:00AM - Photo Session
Coffee Break
- Peter Carmelait, University of Leuven
"VEGF and P1GF: Angiogenic or Neurotrophic Factors?"
- George Yancopoulos, Regeneron Pharmaceuticals, Inc.
"Complementary and Coordinated Roles of VEGF and Angiopoietins"
- Carrie Ambler, Univeristy of North Carolina, Short presentation
"Mouse-Chick Chimeras Reveal Vascular Potential of Mammalian Presomitic Mesoderm"
Monday, July 3 7:30-9:30pm | Cell Interactions & Neovessel Formation |
- Chair: Denisa Wagner, Harvard Medical School
"Adhesion Interactions in the Vasculature"
- Klaus Ley, University of Virginia, School of Medicine
"Integrins & Selectins in Inflammation and Atherosclerosis"
- Rakesh Jain, Massachusetts General Hospital
" Tumor Angiogenesis and Microcirculation"
- Robert Benerzra, Memorial Sloan-Kettering Cancer Center
"The Role of Id Proteins in Angiogenesis"
Tuesday, July 4 9:00am-12:30pm | ECM & Angiogenesis Vascular Bed |
- Chair: Luisa Iruela-Arispe, University of California, Los Angeles
"Regulation of Vascular Morphogenesis by ECM-An Old Theme with New Paradigms"
- Judith Varner, University of California, San Diego
"Fibronectin - Binding Integrins in Angiogenesis"
Coffee Break
- William Stetler-Stevenson, National Institutes of Health
"Metalloproteinase Inhibitors in Regulation of Angiogenesis"
- Nancy Boudreau, University of California, San Francisco, Short presentation
"A Complementary Role for Hox A3 in Endothelial Cell Migration and Angiogenesis" & "Hox D10 Inhibits VEGF andTumor-Induced angiogenesis in the Chick Chorioallantoic Membrane"
Tuesday, July 4 7:30-9:30pm | Smooth Muscle Cell Biology |
- Chair: Gary Owens, University of Virginia
"Rho Dependent Activation of Smooth Muscle Differentiation Marker Genes."
- Mark Majesky, Baylor College of Medicine
"Coronary SMC Differentiation from Proepicardial Cells"
- Levon Khachigian, University of New South Wales
"Catalytic DNA as Tools to Define Transcription Factor Function in the Vascular Response to Injury"
- Pieter Koolwijk, Gaubius Laboratory TNO-PG, Short presentation
"Cleavage of the u-PA Binding Domain of the u-PA Receptor by Endothelial Cell-Derived Matrix Metalloprotease(s): Implication for Angiogenesis in 3-Dimensional Fibrin Matrices in vitro"
Wednesday, July 5 9:00am-12:pm | Signaling |
- Chair: Martin Schwartz, The Scripps Research Institute
"Integrin Signaling in Endothelial Cells"
- Bradford Berk, University of Rochester
"Flow-Mediated Signal Transduction: Kinases and Phosphatases"
Coffee Break
- Shawn Coughlin, University of California, San Francisco
" Thrombin Signaling: Molecular Mechanisms and Roles in vivo."
- Masashi Yanagisawa, Regeneron Pharmaceuticals, Inc.
"Endothelin Signaling in Cardiovascular Homeostasis"
- John Hood, The Scripps Research Institute, Short presentation
"Raf as a Signaling Hub During Angiogenesis"
Wednesday, July 5 7:30-9:30pm | Vascular Biology & Disease |
- Chair: Leslie Parise, University of North Carolina
"New Mechanisms of Sickle RBC Adhesion"
- Peter Libby, Brigham and Women's Hospital
"Molecular Determinants of the Stability of Atherosclerotic Plaques"
- Michael Reidy, University of Washington
"Smooth Muscle Cells and Signal Transduction - Identification of Signaling Pathway Necessary for Proliferation"
- David Ginsburg, University of Michigan
"A Genetic Modifier of Murine von Willebrand Factor Resulting from Altered Lineage Specific Expression of a Glycosyltrasferase"
Thursday, July 6 9:00am-12:30pm | Therapeutic Strategies |
- Chair: Jeffrey Isner, Tufts Medical School
"Endothelial Cell Recruitment in Angiogenesis and Arterial Injury"
- Mark Bednarski, Stanford University
"In-vivo Molecular Imaging of Vascular Receptors: Therapeutic Implications in the Design of Vascular Targeted Radiotherapy"
Coffee Break
- Napolean Ferrara, Genentech, Inc.
"VEGF and Angiogenesis"
- Richard Hynes, Massachusettes Institute of Technology
"To be announced"
- Ed de Muick, Academic Hospital Maastricht, Short presentation
"Conserved Flow-Induced Arterial Remodeling Despite Impaired NO-Dependent Vasodilation in Atherosclerotic and Hypercholesterolemic Mice"
Thursday, July 6 7:30pm | Keynote lecture |
- Leroy Hood, University of Washington
"Genomics, Proteomics and Systems Biology: New Approaches to Vascular Cell Biology"
Party to follow keynote lecture
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