| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 8:30 pm | Keynote Address |
| 7:30 pm | Welcome and Introductory remarks: Luisa Iruela-Arispe, Ph.D. (UCLA, California) |
| Oliver Smithies, Ph.D. (University of North Carolina, Chapel Hill)
"Computer simulations of Complex Biological Systems" |
| 8:30 pm - 9:30 pm | Vascular Stem Cells |
| Discussion Leader: Luisa Iruela-Arispe, Ph.D (UCLA, California) |
| 8:30 pm - 8:50 pm | W.H. Fleming, Ph.D. (Oregon Health and Science University, OR)
"Angiogenic potential of hematopoietic progenitor cells" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Barbara Hempstead, M.D., Ph.D. (Cornell, NY)
"Contribution of pro-angiogenic hematopoietic cells to ischemic revascularization" |
| 9:20 pm - 9:30 pm | Discussion |
| 9:30 pm | Reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Assembly and Patterning of Blood Vessels |
| Discussion Leader: Victoria Bautch, Ph.D. |
| 9:00 am - 9:20 am | Holger Gerhardt, Ph.D. (London Research Institute, UK)
"Vascular patterning and heterotypic cell interactions" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | David Anderson, Ph.D. (Caltech, California)
"Novel genes that regulate endothelial differentiation" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Dean Li, M.D., Ph.D. (University of Utah)
"Mechanisms of Robo4 Signaling" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Lijun Xia, Ph.D. (Ohio State Univ., OH)
"Contribution of core 1-derived O-glycans in endothelial cells to vascular development" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 11:30 am | Group Photo / Coffee Break |
| 11:30 am - 11:50 am | Guillermo Oliver, Ph.D. (St. Jude Children's Hosp., TN)
"Assembly of Lymphatics" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | To be selected from the abstracts submitted |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Cell Signaling in Vascular Biology |
| Discussion Leader: David Anderson, Ph.D. |
| 7:30 pm - 7:50 pm | Takashi Mikawa, Ph.D. (Cornell, NY)
"The suppression of vascular development by BMP antagonism" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Jan Kitajewski, Ph.D. (Columbia Univ., NY)
"Notch signaling in vascular development and vessel pathology" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Nicholas Gale, Ph.D. (Regeneron, NY)
"Inductive signaling by Delta 4" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Mark Majesky, Ph.D. (Univ. North Carolina)
"Signaling in the pro-epicardial organ" |
| 9:20 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Lumen formation and Mechanotransduction |
| Discussion Leader: Mark Majesky, Ph.D. (University of North Carolina) |
| 9:00 am - 9:20 am | George Davis, M.D., Ph.D. (Texas A&M, TX)
"MMPs in endothelial cell lumen formation and stability" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Tanmay Lele, Ph.D. (Harvard Med. School, MA)
"Biophysical basis of tension-dependent control of focal adhesion assembly in capillary endothelial cells" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Martin Schwartz, Ph.D. (University of Virgina, VA)
"Adhesion receptors in the fluid shear stress response" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:20 am | Elisabetta Dejana, Ph.D. (Milan, Italy)
"JAM-A and leukocyte infiltration in inflamed tissues" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | Michael Simons, M.D. (Dartmouth, NH)
"Arteriogenesis and arterial branching" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | To be selected from the abstracts submitted |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Thrombosis and Vascular Physiology |
| Discussion Leader: Elisabetta Dejana, Ph.D. (Milan, Italy) |
| 7:30 pm - 7:50 pm | Mark Taubman, M.D. (Rochester Univ., NY)
"The changing face of tissue factor biology: identification of novel TF variants and the role of TF in mediating non-thrombotic cardiovascular pathology" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Nigel Mackman, Ph.D. (Scripps, CA)
"Role of tissue factor in thrombosis and inflammation" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Han Mou Tsai, M.D. (Univ. of Washington, Seattle)
"ADAMTS13 for thrombotic thrombocytopenic purpura - Does size matter?" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Shaun Coughlin, M.D., Ph.D. (UCSF, CA)
"Protease-activated receptors in thrombosis and vascular biology" |
| 9:20 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Homeostatic regulation of vascular function |
| Discussion Leader: Shaun Coughlin, M.D., Ph.D. (UCSF, CA) |
| 9:00 am - 9:20 am | Celeste Simon, Ph.D. (University of Pennsylvania, PA)
"Oxygen Homeostasis and Angiogenesis" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Joan Taylor, Ph.D. (Univ. of North Carolina, MD)
"Focal adhesion kinase signaling in the vasculature" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Tanya Mayadas, Ph.D. (Harvard Med. School, MA)
"Phagocyte low affinity Fc gamma receptors: signaling and functions in vitro and in vivo" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:20 am | Guillermo Garcia-Cardena, Ph.D. (Harvard Medical School, Boston)
"Unveiling a master regulator of endothelial function" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | Elena Galkina, Ph.D. (Univeristy of Virgina)
"Constitutive homing of T- and B- lymphocytes into aortic wall under normal/non-inflamed conditions" |
| 11:50 am - 12:00 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | New Technological Developments and Vascular Biology |
| Discussion Leader: Celeste Simon, Ph.D. (Univ. of Pennsylvania) |
| 7:30 pm - 7:50 pm | Andras Nagy, Ph.D. (Mount Sinai Hospital, Canada)
"What is new in the manipulation of the mouse genome?" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Mary Dickinson, Ph.D. (Caltech, CA)
"Imaging at the speed of cells: understanding hemodynamics and vascular remodeling in the developing yolk sac" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Karen Hirschi, Ph.D. (Baylor, TX)
"Signaling hierarchy and vascular remodeling" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Brian Helmke, Ph.D. (Univ. of Virginia, VA)
"Probing mechanosensitive structural dynamics in vascular cells with nanoscale tools" |
| 9:20 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Vascular Disease - Basic Biology and Clinical Implications |
| Discussion Leader: Mark Taubman, M.D. (University of Rochester, NY) |
| 9:00 am - 9:20 am | Bradford Berk, M.D. (University of Rochester, NY)
"Novel Mechanisms for clinical benefits of renin angiotensin blockade" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Randy Johnson, Ph.D. (UCSD, CA)
"Confounding factors in vascular disease" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Robert Feil, Ph.D. (Technische Universitat, Munchen, Germany)
"NO/cGMP signaling in smooth muscle cells and atherosclerosis" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:20 am | Rama Natarajan, Ph.D. (Beckman Res. Inst. - City of Hope, CA)
"Chromatin remodeling and inflammatory gene transcription related to diabetic vascular disease" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | To be selected from the abstracts submitted |
| 11:50 am - 12:00 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Genetic and Cellular Basis of Vascular Disease |
| Discussion Leader: Steve Schwartz, M.D. (Univ. of Washington, WA) |
| 7:30 pm - 7:50 pm | Jake Lusis, Ph.D. (UCLA, CA)
"Multiple genetic factors in the regulation of atherosclerosis" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Susan Smyth, M.D., Ph.D. (Univ. North Carolina)
"Lysophospholipid signaling in vascular disease" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:20 pm | Peter Tontonoz, Ph.D. (UCLA, Los Angeles, CA)
"PPRgamma and vascular disease" |
| 9:20 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
