| Sunday PM |
Receptors and membrane fusion |
| 6:00pm |
Dinner |
| 7:15pm |
Introduction/Welcome |
| 7:30pm |
Gary Cohen (University of Pennsylvania), discussion leader
Introduction to session |
| 7:40pm |
Joshua Zimmerberg (National Institute of Child Health & Human Development)
Membrane Fusion |
| 8:05pm |
Discussion |
| 8:15pm |
Roselyn J. Eisenberg (University of Pennsylvania School of Veterinary Medicine)
Receptor-gD interactions involved in HSV entry into mammalian cells |
| 8:40pm |
Discussion |
| 8:50pm |
Don C. Wiley (Harvard University)
Structural studies of viral entry in influenza, HIV-1 and Ebola viruses |
| 9:15pm |
Discussion |
| 9:25pm |
Ted Jardetzky (Northwestern University)
Structural basis for paramyxovirus-mediated membrane fusion |
| 9:35pm |
Discussion |
| Monday AM |
Transport, processing and trafficking of viral macromolecules |
| 9:00am |
Peter Palese (Mt. Sinai School of Medicine), discussion leader
Introduction to session |
| 9:10am |
Ari Helenius (Swiss Federal Institute of Technology Zurich)
Folding of viral glycoproteins |
| 9:35am |
Discussion |
| 9:45am |
Robert M. Krug (Rutgers University)
The influenza virus NS1 protein interacts with an essential component of the 3' end processing machinery of the cell to cause the selective inhibition of the nuclear export of cellular, and not viral, mRNAs |
| 10:10am |
Discussion |
| 10:20am |
Michael Bukrinsky (The Picower Institute for Medical Research)
HIV nuclear import |
| 10:45am |
Discussion |
| 10:55am |
Coffee break and group photograph |
| 11:10am |
Peter O'Hare (Marie Curie Research Institute)
Structural proteins of herpes simplex virus in non-structural roles |
| 11:35am |
Discussion |
| 11:45am |
Morgane Bomsel (Institut Cochin de Génétique Moléculaire)
Mechanism of infectious HIV penetration across a tight epithelial barrier |
| 11:55am |
Discussion |
| 12:00am |
Michael Whitt (University of Tennessee-Memphis)
The membrane-proximal stem of VSV G acts as a fusion potentiator and allows chemokine coreceptor-independent entry of VSV-CD4 recombinants into HIV-Env(+) cells |
| 12:10pm |
Discussion |
| 12:30pm |
Lunch |
| Monday PM |
Genome replication and polymerases |
| 5:30pm |
Karla Kirkegaard (Stanford University), discussion leader
Introduction to session |
| 5:40pm |
Sandra Weller (University of Connecticut Health Center)
DNA replication and genome maturation in herpes simplex virus |
| 6:05pm |
Discussion |
| 6:15pm |
Paula Traktman (Medical College of Wisconsin)
Vaccinia virus replication: Do the ends provide the means? |
| 6:40pm |
Discussion |
| 6:50pm |
Steve C. Schultz (University of Colorado)
Structural studies of poliovirus polymerase |
| 7:15pm |
Discussion |
| 8:00pm |
Dinner |
| Tuesday AM |
Host determinants of infection and oncogenesis |
| 9:00am |
Patrick Moore (Columbia University), discussion leader
Introduction to session |
| 9:10am |
Lawrence Banks (International Centre for Genetic Engineering and Biotechnology)
Interactions between HPV oncoproteins and cellular tumor suppressors |
| 9:35am |
Discussion |
| 9:45am |
Yuan Chang (Columbia University College of Physicians & Surgeons)
Transcriptional regulation of cMyc by KSHV |
| 10:10am |
Discussion |
| 10:20am |
Michael G. Katze (University of Washington)
Virus-host interactions and molecular mechanisms of drug resistance: lessons to be learned from hepatitis C |
| 10:45am |
Discussion |
| 10:55am |
Coffee break |
| 11:10am |
Michel Brahic (Institut Pasteur)
Genetics of the persistence of Theiler's virus |
| 11:35am |
Discussion |
| 11:45am |
Daniel DiMaio (Yale University)
The PDGF receptor as a mediator of bovine papillomavirus transformation |
| 11:55am |
Discussion |
| 12:00am |
Carl Ware (La Jolla Institute for Allergy and Immunology)
Lymphotoxins as deterrents to infection by herpesvirus |
| 12:10pm |
Discussion |
| 12:30pm |
Lunch |
| Tuesday PM |
Viral pathogenesis |
| 5:00pm |
Ed Mocarski (Stanford University), discussion leader
Introduction to session |
| 5:10pm |
Eileen White (Rutgers University Center for Advanced Biotechnology and Medicine)
Regulation of apoptosis by the transforming genes of adenovirus |
| 5:35pm |
Discussion |
| 5:45pm |
Nancy C. Reich (State University of New York at Stony Brook)
Cellular response to viral infection and dsRNA |
| 6:10pm |
Discussion |
| 6:20pm |
Eckard Wimmer (State University of New York at Stony Brook School of Medicine)
Poliovirus neurovirulence and expression of the poliovirus receptor CD155 |
| 6:45pm |
Discussion |
| 6:55pm |
Ronald Swanstrom (University of North Carolina Lineberger Cancer Center)
Dynamic behavior of HIV-1 populations in vivo |
| 7:20pm |
Discussion |
| 8:00pm |
Dinner |
| Wednesday AM |
Structural studies of viral proteins and RNAs |
| 9:00am |
John Skehel (Natl. Inst. for Medical Research, Mill Hill), discussion leader
Introduction to session |
| 9:10am |
Raffaele De Francesco (Instituto di Recherch di Biologia Moleculare)
Hepatitis C virus NS3 protein: Differential regulation of the proteinase and helicase activities |
| 9:35am |
Discussion |
| 9:45am |
Jennifer A. Doudna (Yale University)
Crystal structure of a hepatitis delta virus ribozyme: Clues to catalysis and regulation |
| 10:10am |
Discussion |
| 10:20am |
Richard Wyatt (Dana-Farber Cancer Institute)
Structural Analysis of the HIV-1 Exterior Envelope Glycoprotein, gp120 |
| 10:45am |
Discussion |
| 10:55am |
Coffee break |
| 11:10am |
Stephen C. Harrison (Harvard University)
Atomic structure of the reovirus core |
| 11:35am |
Discussion |
| 11:45am |
Glen Nemerow (Scripps Research Institute)
Structure and kinetic analyses of integrin avb5 association with human adenovirus |
| 11:55am |
Discussion |
| 12:00am |
Paul Freimuth (Brookhaven National Laboratory)
Crystal structure of the adenovirus-12 fiber knob in complex with domain 1 of its cellular receptor CAR |
| 12:10pm |
Discussion |
| 12:15pm |
Marianne Manchester (Scripps Research Institute)
A novel strategy for inhibiting virus entry using a cellular receptor-plant virus chimera |
| 12:25pm |
Discussion |
| 12:30pm |
Lunch |
| Wednesday PM |
Viral perturbation of host functions |
| 5:30pm |
Robert Schneider (New York University), discussion leader
Introduction to session |
| 5:40pm |
Richard Longnecker (Northwestern University Medical School)
Epstein-Barr virus LMP2A: A regulator or means for viral persistence |
| 6:05pm |
Discussion |
| 6:15pm |
Melanie Spriggs (Immunex Corporation)
The biology of virus encoded semaphorins and their cellular receptor |
| 6:40pm |
Discussion |
| 6:50pm |
Tomas Kirchhausen (Harvard University School of Medicine)
Collision of sorts: viruses, viral proteins and clathrin-dependent traffic |
| 7:15pm |
Discussion |
| 8:00pm |
Dinner |
| Thursday AM |
Viruses and the immune system |
| 9:00am |
Melanie Spriggs (Immunex Corporation), discussion leader
Introduction to session |
| 9:10am |
Lewis Lanier (DNAX Research Institute for Molecular and Cellular Biology)
NK cell recognition |
| 9:35am |
Discussion |
| 9:45am |
Rafi Ahmed (Emory Vaccine Center)
Immune memory to viruses |
| 10:10am |
Discussion |
| 10:20am |
John Altman (Emory Vaccine Center)
The new math of anti-viral T cell responses |
| 10:45am |
Discussion |
| 10:55am |
Coffee break |
| 11:10am |
Bernard Moss (NIAID, NIH)
Host immune defense molecules encoded by molluscum contagiosum virus |
| 11:35am |
Discussion |
| 11:45am |
Ganes Sen (Cleveland Clinic Foundation)
New pathways of cellular regulation by interferons and double-stranded RNA |
| 11:55am |
Discussion |
| 12:00am |
Paula Pitha-Rowe (Johns Hopkins University)
The role of transcriptional factors of IRF family in virus-mediated signalling and mimicry |
| 12:10pm |
Discussion |
| 12:20pm |
Business meeting |
| 12:30pm |
Lunch |
| Thursday PM |
Epidemiology, Prevention and Therapy |
| 5:30pm |
Pat Spear (Northwestern University Medical School), discussion leader
Introduction to session |
| 5:40pm |
Jack Rose (Yale University School of Medicine)
Redesigning the VSV Envelope |
| 6:05pm |
Discussion |
| 6:15pm |
Nancy Davis (University of North Carolina at Chapel Hill)
Replicon vaccines based on Venezuelan equine encephalitis virus |
| 6:40pm |
Discussion |
| 6:50pm |
Douglas Lowy (National Cancer Institute)
Papillomaviruses: vaccines, vectors, and virology |
| 7:15pm |
Discussion |
| 8:00pm |
Dinner |
