| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 5:00 pm | Akzo Nobel Intervet International bv Welcome Reception |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Structure and Assembly |
| Co-discussion leaders: John Skehel and Michael Rossmann |
| 7:30 pm | Welcome |
| 7:40 pm | Introduction: Don Wiley Tribute |
| 7:50 pm | Keynote speaker: Stephen Harrison - Harvard University |
| 8:20 pm | Discussion |
| 8:30 pm | Richard Kuhn - Purdue University
"Structure and assembly of alpha- and Flaviviruses" |
| 8:50 pm | Discussion |
| 9:00 pm | Felix Rey - CNRS, Laboratoire de Génétique des Virus
"Structure of class II viral membrane-fusion proteins" |
| 9:20 pm | Discussion |
| 9:45 pm | Merck and Co., Inc. Reception and POSTER SESSION 1A |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Synthesis, Processing, and Trafficking of Viral Proteins |
| Co-discussion leaders: Margaret Kielian and Pat Spear |
| 9:00 am | Introduction |
| 9:15 am | Heinz-Juergen Thiel - Universitaet Giessen
"Cellular sequences in pestiviruses alter polyprotein processing and biotype" |
| 9:35 am | Discussion |
| 9:45 am | Greg Smith - Northwestern University Medical School
"Herpesvirus transport in sensory neurons" |
| 10:05 am | Discussion |
| 10:15 am | Coffee Break and Group Photo |
| 10:50 am | Michael Way - Lincoln's Inn Fields Laboratories
"How vaccinia virus uses and abuses the cytoskeleton" |
| 11:10 am | Discussion |
| 11:20 am | Douglas Lyles - Wake Forest University School of Medicine
"Mutation of a hydrophobic loop in the matrix protein of vesicular stomatitis virus dissociates nucleocapsid-binding and membrane-binding activities"
|
| 11:30 am | Discussion |
| 11:35 am | Yorgo Modis - Harvard Medical School
"Crystal structure of the dengue 2 virus envelope glycoprotein"
|
| 11:45 am | Discussion |
| 11:50 am | Urs Greber - University of Zurich
"Trafficking in Adenovirus Entry"
|
| 12:00 pm | Discussion |
| 12:05 pm | Roy Duncan - Dalhousie University
"Membrane Fusion Progreins from Nonenveloped Viruses"
|
| 12:15 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 5:30 pm | Free Time |
| 5:30 pm - 7:30 pm | Viral Replication and Gene Expression |
| Co-chairs: Dan Kolakofsky and Gail Wertz |
| 5:30 pm | Introduction |
| 5:45 pm | Karla Kirkegaard - Stanford University
"Cell biology, biochemistry and genetics of poliovirus RNA replication" |
| 6:05 pm | Discussion |
| 6:15 pm | Andy Ball - University of Alabama
"Replication and Assembly of Small RNA Viruses of Insects" |
| 6:35 pm | Discussion |
| 6:45 pm | Yoshihiro Kawaoka - University of Tokyo
"Influenza virus: recent advances" |
| 7:05 pm | Discussion |
| 7:15 pm | Thomas Mettenleiter - Friedrich Loeffler Institutes
"Assembly and Egress of Herpesviruses" |
| 7:35 pm | Discussion |
| 8:00 pm | Dinner |
| 9:30 pm | POSTER SESSION 1B |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Receptors, Membrane Fusion, Entry |
| Co-discussion leaders: Robert Doms and Robert Lamb |
| 9:00 am | Introduction to session |
| 9:15 am | John P. Moore - Cornell University, Weill Medical College
"Inhibiting HIV-1 entry with drugs and antibodies as an approach to prevention and treatment" |
| 9:35 am | Discussion |
| 9:45 am | Terence Dermody - Vanderbilt University
"Cellular determinants of reovirus attachment and entry" |
| 10:05 am | Discussion |
| 10:15 am | Coffee Break |
| 10:50 am | Judy White - University of Virginia
"Mechanisms of Activating Viral Membrane Fusion Proteins" |
| 11:10 am | Discussion |
| 11:20 am | Max Nibert - Harvard Medical School
"Membrane penetration by a large nonenveloped virus, orthoreovirus" |
| 11:40 am | Discussion |
| 11:50 am | Peter Bredenbeek - Leiden University Medical Center
"Functional analysis of predicted RNA pseudoknot structures in the 3'-NTR of yellow fever virus" |
| 12:00 pm | Discussion |
| 12:05 pm | Darius Moradpour - University of Freiburg
"Interactions of hepatitis C virus with host cell membranes" |
| 12:15 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 5:30 pm | Free Time |
| 5:30 pm - 7:30 pm | Virus-Immune System Interactions |
| Discussion leader: Ulrich Koszinowski |
| 5:30 pm | Introduction |
| 5:45 pm | Aron Lukacher - Emory University School of Medicine
"Inhibition of antiviral CTL by NK cell receptors: role in conferring susceptibility to polyoma virus-induced tumors" |
| 6:05 pm | Discussion |
| 6:15 pm | Lewis Lanier - University of California
"NK cell recognition of viruses" |
| 6:35 pm | Discussion |
| 6:45 pm | Hidde Ploegh - Harvard Medical School
"Cytomegalovirus: a profound dislike of killer cells" |
| 7:05 pm | Discussion |
| 7:15 pm | Antonio Alcami - University of Cambridge Addenbrooke's Hospital
"Modulation of cytokine and chemokine networks by viruses" |
| 7:35 pm | Discussion |
| 8:00 pm | Dinner |
| 9:30 pm | POSTER SESSION 2A |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Pathogenesis |
| Co-discussion leaders: Frank Chisari and Diane Griffin |
| 9:00 am | Introduction |
| 9:15 am | Juan Carlos de la Torre - The Scripps Research Institute
"Virus-cell interactions in the brain" |
| 9:35 am | Discussion |
| 9:45 am | Ann Arvin - Stanford University
"Investigations of Varicella-Zoster Virus Tropism for Human T cells and Skin" |
| 10:05 am | Discussion |
| 10:15 am | Coffee Break |
| 10:50 am | Matthias von Herrath - The Scripps Research Institute
"Viruses and the regulation of autoimmunity - enhancement or prevention?" |
| 11:10 am | Discussion |
| 11:20 am | Simon Wain-Hobson - Institut Pasteur
"Attenuated vaccines and AIDS pathogenesis" |
| 11:40 am | Discussion |
| 11:50 am | Stephanie Karst - Washington University School of Medicine
"Requirement of STAT1-Dependent Innate Immunity for Mouse Norovirus 1 Resistance"
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| 12:00 pm | Discussion |
| 12:05 pm | Glenn Rall - Fox Chase Cancer Center
"The role of maternal immunity in susceptibility to measles virus infection and disease"
|
| 12:15 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 5:30 pm | Free Time |
| 5:30 pm - 7:30 pm | Stress, Interferon, and Innate Immune Responses |
| Discussion Leader: Ganes Sen |
| 5:30 pm | Introduction |
| 5:45 pm | Giorgio Trinchieri - Schering-Plough
"Type I interferon-producing cells: their role in innate and adaptive immunity" |
| 6:05 pm | Discussion |
| 6:15 pm | Bryan Williams - Cleveland Clinic Foundation
"Innate immunity signaling and protein kinase R" |
| 6:35 pm | Discussion |
| 6:45 pm | David Levy - New York University School of Medicine
"IRF and Stat transcription factors in the battle between viruses and interferons" |
| 7:05 pm | Discussion |
| 7:15 pm | Teresa Compton - University of Wisconsin
"Activation of Host Innate Defenses to Herpesviruses via Toll-like Receptors" |
| 7:35 pm | Discussion |
| 8:00 pm | Dinner |
| 9:30 pm | POSTER SESSION 2B |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Modulation of Virus/Host Interactions |
| Co-discussion leaders: Geoffrey Smith and Vicki Vance |
| 9:00 am | Introduction |
| 9:15 am | Shouwei Ding - University of California
"Adaptive antiviral defense by RNA silencing - a drosophila model" |
| 9:35 am | Discussion |
| 9:45 am | Jae Jung - Harvard Medical School
"gamma-2 herpesvirus; a very selfish virus" |
| 10:05 am | Discussion |
| 10:15 am | Coffee Break |
| 10:50 am | Grant McFadden - Univ of Western Ontario and Robarts Res Inst
"Anti-immune strategies by poxviruses" |
| 11:10 am | Discussion |
| 11:20 am | Curt Horvath - Mount Sinai School of Medicine
"Regulation of the Anti-Viral Responses: STAT Targeting by Paramyxoviruses" |
| 11:40 am | Discussion |
| 11:50 am | Luis Sigal - Fox Chase Cancer Center
"Macrophages and Dendritic cells use the cytosolic pathway to rapidly cross-present antigen from live, vaccinia-infected cells" |
| 12:00 pm | Discussion |
| 12:05 pm | Brenda Fredericksen - University Texas Southwestern Medical Ctr
"Characterization of the Host Response to West Nile Virus" |
| 12:15 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 5:30 pm | Free Time |
| 5:30 pm - 7:30 pm | Virus Evolution |
| Discussion leader: Luis Villareal |
| 5:30 pm | Introduction |
| 5:45 pm | Gary Hayward - John Hopkins University School of Medicine
"Modern Evolutionary History and Chimerism in the Kaposi's Sarcoma Associated Herpesvirus (KSHV) Genome" |
| 6:05 pm | Discussion |
| 6:15 pm | Jaap Goudsmit - Crucell NV
"Adenoviruses and DC Tropism: the relationship to T cell responses in vitro and in vivo" |
| 6:35 pm | Discussion |
| 6:45 pm | Marilyn Roossinck - Samuel Roberts Noble Foundation
"Biology of RNA Virus Quasispecies" |
| 7:05 pm | Discussion |
| 7:15 pm | David Mindell - University of Michigan
"Viruses and the Tree of Life"
|
| 7:35 pm | Discussion |
| 8:00 pm | Dinner |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
