SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
5:00 pm - 6:00 pm | Welcome Reception |
6:00 pm | Dinner |
7:25 pm | Welcome to the meeting and scientific sessions |
7:30 pm - 9:30 pm | Structure of viral proteins, RNAs and virions |
| Discussion Leaders: Richard Kuhn, Purdue University & Felix Rey, CNRS, Paris |
7:30 pm - 7:50 pm | Daved Fremont, Washington University
"Structural mechanisms of virally encoded immune evasion proteins" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Ming Luo, University of Alabama at Birmingham
"Structural studies of vesicular stomatitis virus proteins" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | James Stevens, The Scripps Research Institute
"Structural and functional insights to the 1918 Flu Pandemic" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Dave Stuart, Oxford University
"Further fun with fatty phages" |
9:20 pm - 9:30 pm | Discussion |
9:30 pm | Reception and Poster session 1A |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Receptors, entry, membrane fusion |
| Discussion Leader: Terence Dermody, Vanderbilt University & John Young, Salk Institute for Biological Studies |
9:00 am - 9:20 am | Jeff Bergelson, The Children's Hospital of Philadelphia
"Virus-induced signals that permit coxsackievirus entry through the tight junction of polarized epithelial cells" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Gabriella Campadelli-Fiume, University of Bologna
"Dissecting HSV entry: a quartet in concert" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:45 am | Coffee Break / Group Photo |
10:45 am - 11:05 am | Margaret Kielian, Albert Einstein College of Medicine
"Functional studies of a class II virus membrane fusion protein" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:35 am | Bernard Moss, NIH/NIAID
"Poxvirus entry/fusion proteins" |
11:35 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Sonia Longhi, CNRS & Universities AIX-Marseille I and II
"The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct sites and remains predominantly unfolded" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Edward Berger, NIAID, Laboratory of Viral Diseases
"KSHV Fusion: Target cell tropism and identification of a fusion/entry receptor by functional cDNA selection" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Robert Lamb, HHMI/Northwestern University
"Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 5:00 pm | Free Time |
5:30 pm - 7:30 pm | Translation, transcription, replication |
| Discussion Leaders: Andrew Ball, University of Alabama at Birmingham & Rozanne Sandri-Goldin, University of California, Irvine |
5:30 pm - 5:50 pm | Peter Sarnow, Stanford University
"Modulation of hepatitis C virus gene expression by a liver-specific microRNA" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Ralf Bartenschlager, University of Heidelberg
"Production of infectious hepatitis C virus in cell culture: Lessons from studies with replicons" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Neal DeLuca, University of Pittsburgh School of Medicine
"Regulation of HSV early and late transcription: Role of ICP4" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Roger Everett, MRC Division of Virology, Glasgow
"What role do PML nuclear bodies play in HSV-1 infection?" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
9:30 pm | Reception and Poster session 1B |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Assembly, budding and release |
| Discussion Leaders: Paul Bieniasz, The Aaron Diamond AIDS Research Center & Paula Traktman, Medical College of Wisconsin |
9:00 am - 9:20 am | Wesley Sundquist, University of Utah
"The biochemistry of HIV budding" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Richard Condit, University of Florida
"Genetic analysis of the role of core proteins in vaccinia virus morphogenesis" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:10 am | Sheri Hanna, University of Pennsylvania
"N-linked glycosylation of West Nile virus envelope proteins influences particle assembly and infectivity" |
10:10 am - 10:15 am | Discussion |
10:15 am - 10:45 am | Coffee break |
10:45 am - 11:00 am | Business Meeting |
11:00 am - 11:20 am | Winfried Weissenhorn, EMBL Grenoble
"Structure and function of cellular proteins implicated in virus budding" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Thomas Wileman, Institute for Animal Health, Pirbright
"Movement of African Swine Fever virus from aggresomes to the tip of filopodia" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | John Taylor, Fox Chase Cancer Center
"Learning from the transcription and replication of hepatitis delta virus" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Ian Mohr, New York University School of Medicine
"Assembly of an active translation initiation factor complex by the HSV-1 ICP6 protein allows for the correct apposition of the eIF4E kinase with its substrate" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 5:00 pm | Free Time |
5:30 pm - 7:30 pm | Virus-host interactions and host restriction |
| Discussion Leaders: Grant McFadden, The John P. Robarts Research Institute & Didier Trono, Centre Medical Universitaire, Geneva |
5:30 pm - 5:50 pm | Paul Ahlquist, University of Wisconsin
"Virus-host interactions in positive-strand RNA virus replication" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Michele Barry, University of Alberta
"Vaccinia virus regulates the mitochondrial checkpoint in apoptotic cells" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Klaus Freuh, Oregon Health Sciences University
"Immune modulation by a family of viral and cellular ubiquitin ligases" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Michael Malim, King's College
"Natural resistance to HIV infection: the Vif-APOBEC interaction" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
9:30 pm | Reception and Poster Session 2A |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Stress, TLRs and interferon |
| Discussion Leaders: Teresa Compton, University of Wisconsin & Otto Haller, University of Freiburg |
9:00 am - 9:20 am | Bruce Beutler, The Scripps Research Institute
"Forward genetic analysis of innate immune responses" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Akiko Iwaski, Yale University
"Innate recognition of viruses by dendritic cells" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:10 am | James Alwine, University of Pennsylvania School of Medicine
"Human cytomegalovirus infection activates and regulates the unfolded protein response" |
10:10 am - 10:15 am | Discussion |
10:15 am - 10:45 am | Coffee Break |
10:45 am - 11:05 am | John Hiscott, McGill University
"TLR-dependent and independent pathways leading to the interferon antiviral response" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:35 am | Michael Gale, Jr., University of Texas, Southwestern Medical Center
"Virus-host regulation of IRF-3" |
11:35 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Dominique Garcin, CMU-Geneva
"The modular nature of the Sendai virus accessory C protein" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Lori Frappier, University of Toronto
"EBNA1-HAUSP (USP7) interaction: Implications for cell immortalization by Epstein-Barr virus" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | David Bloom, University of Florida College of Medicine
"A chromatin insulator-like element positioned between the HSV-1 LAT enhancer and ICP0 promoter has cell type-specific enhancer-blocking activity" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 5:00 pm | Free Time |
5:30 pm - 7:30 pm | Immune system interactions |
| Discussion Leaders: Harry Greenberg, Stanford University & Paul Klenerman, John Radcliffe Hospital |
5:30 pm - 5:50 pm | Antonio Lanzavecchia, Institute for Research in Biomedicine, Bellinzona, Switzerland
"Vaccination and immunological memory" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Kim Hasenkrug, NIH/NIAID
"Immunomodulation by chronic infection" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Christine Biron, Brown University
"Accessing the wide range of interferon effects" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | M.B.A. Oldstone, The Scripps Research Institute
"Anatomy of persistence: viruses subvert the immune system through type-1 interferon mediated stat-2 dependent signalling" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
9:30 pm | Reception and Poster Session 2B |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Pathogenesis |
| Discussion Leader: Ann Arvin, Stanford University |
9:00 am - 9:20 am | Lynn Enquist, Princeton University
"Axonal targeting and trans-neuronal spread of PRV" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Vincent Racaniello, Columbia University
"Picornavirus pathogenesis" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:10 am | Shane Crotty, La Jolla Institute for Allergy and Immunology
"SAP/SH2D1A regulation of T and B cell responses and the control of a chronic viral infection" |
10:10 am - 10:15 am | Discussion |
10:15 am - 10:45 am | Coffee Break |
10:45 am - 11:05 am | David Thorley-Lawson, Tufts University
"Host virus interactions in persistent EBV infection" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:35 am | Chris Walker, Columbus Children's Research Institute
"Discordant immune selection pressure against MHC class I versus class II epitopes of the hepatitis C virus" |
11:35 am - 11:45 am | Discussion |
11:45 am - 11:55 am | William Halford, Montana State University
"Host interferons and viral ICP0: two opposing forces that create an ON-OFF switch in the herpes simplex virus life cycle" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Beate Sodeik, Hannover Medical School
"The inner tegument of herpes simplex virus promotes capsid transport along microtubules in vitro" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Michael Diamond, Washington University School of Medicine
"The structural basis of antibody-mediated neutralization of West Nile virus" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 5:00 pm | Free Time |
5:30 pm - 7:30 pm | Virus evolution, epidemiology, prevention and therapy |
| Discussion Leaders: Alice Telesnitsky, University of Michigan Medical School & Simon Wain-Hobson, Institut Pasteur |
5:30 pm - 5:50 pm | Mary Estes, Baylor College of Medicine
"Norwalk virus genome replication in mammalian cells: Opportunities for new therapeutics" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Ben Berkhout, University of Amsterdam
"HIV-1 evolutionary strategies" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Alice Telesnitsky, University of Michigan
"Host sequence transduction by HIV" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Colin Parrish, Cornell University
"Parvovirus evolution and the control of host range - influences of specific receptor binding by the capsids and the role of antigenic selection" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |