SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:35 pm | Welcome / Introductory Comments by GRC Site Staff |
7:35 pm - 9:30 pm | Virus Entry and Assembly |
| Discussion Leader: Rebecca Dutch (University of Kentucky) |
7:35 pm - 7:55 pm | Keynote Presentation: Stephen Harrison (Harvard Medical School)
"Entry mechanisms for non-enveloped viruses"
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7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:25 pm | Priscilla Yang (Harvard Medical School)
"Chemical Approaches to the Study of Dengue Virus Entry"
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8:25 pm - 8:35 pm | Discussion |
8:35 pm - 8:55 pm | Matthew Evans (Icahn School of Medicine at Mount Sinai)
"The complexities of hepatitis C virus host cell entry"
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8:55 pm - 9:05 pm | Discussion |
9:05 pm - 9:25 pm | Brett Lindenbach (Yale University)
"In a network of lines that enlace: the interplay between hepatitis C virus replication and assembly"
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9:25 pm - 9:30 pm | Discussion |
9:30 pm - 10:30 pm | Welcome Reception (LaVeranda Terrace) |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | The Intricacies of Viral Replication |
| Discussion Leaders: Yves Gaudin (CNRS, Gif sur Yvette., France) and Wendy Barclay (Imperial College., London, UK) |
9:00 am - 9:20 am | Craig Cameron (Penn State University)
"Contributions of HCV NS5a phosphorylation to viral replication and viral persistence"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Erica Ollman Saphire (Scripps Research Institute)
"The filovirus matrix: protein plasticity permits multiple functions"
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9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Group Photo / Coffee Break |
10:30 am - 10:50 am | Sandra K. Weller (University of Connecticut)
"Manipulation of Host Stress Response pathways by Herpes Simplex Virus"
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10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Peter Cresswell (Yale University)
"Viperin: a central regulator of metabolic changes induced by HCMV infection"
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11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Everett Smith (Vanderbilt University)
"Coronaviruses lacking exoribonuclease activity are susceptible to multiple RNA mutagens: implications for viral evolution and therapeutics" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Noam Stern-Ginossar (University of California, San Francisco)
"Decoding human cytomegalovirus by ribosome profiling" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Yael Mutsafi (Weizmann Institute of Science)
"Membrane assembly during the infection cycle of the giant mimivirus" |
12:10 pm - 12:15 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session I |
5:30 pm - 7:30 pm | Viral Manipulation of Cellular Membranes and Lipids |
| Discussion Leader: Richard Kuhn (Purdue University) |
5:30 pm - 5:50 pm | Nihal Altan-Bonnet (Rutgers University)
"Panviral Lipid Remodeling for Replication"
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5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Glenn Randall (University of Chicago)
"Manipulation of cellular lipid synthesis and signaling in viral replication compartment formation"
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6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Jeanmarie Verchot (Oklahoma State University)
"Linking the endoplasmic reticulum and unfolded protein response to plant virus movement proteins"
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6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Sriram Subramaniam (NCI/NIH)
"3D Imaging of HIV entry"
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7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
9:30 pm | Poster Session I (continued - presenters will be at their posters) |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Viral Manipulation of Nuclear/Cellular Functions |
| Discussion Leaders: David Knipe (Harvard Medical School) and Cristina Risco (CNB, Madrid ESP) |
9:00 am - 9:20 am | Michael Way (London Research Institute, UK)
"Subversion of signalling and cytoskeletal function by vaccinia virus"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Robert Garcea (University of Colorado, Boulder)
"Nuclear Factories for Polyomavirus Assembly"
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9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Alison McBride (NIAID/NIH)
"Replication and Maintenance of Papillomaviruses by Manipulation of Host Chromatin Processes"
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10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Lori Frappier (University of Toronto, Canada)
"EBNA1-Host Interactions Contribute to Cell Immortalization and Reactivation of Epstein-Barr Virus"
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11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Daniel DiMaio (Yale University)
"Role of the retromer in HPV entry" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Covadonga Alonso (INIA, Madrid Spain)
"Building the viral replication organelle by a double stranded DNA virus" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Jason Botten (University of Vermont)
"The Intracellular Cargo Receptor ERGIC-53 Is Required for the Formation of Infectious Arenavirus Particles" |
12:10 pm - 12:15 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session I (continued) |
5:30 pm - 7:30 pm | Virus-Mediated Changes in Transcriptional & Translational Control |
| Discussion Leader: Roz Sandri-Goldin (UC Irvine) |
5:30 pm - 5:50 pm | Britt Glaunsinger (University of California at Berkeley)
"RNA-based manipulation of host and viral gene expression by gammaherpesviruses"
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5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Chris Sullivan (University of Texas at Austin)
"RNAi: A Tool for the Enemy During Viral Infection of Mammalian Cells"
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6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Ian Mohr (New York University)
"Control of herpes simplex virus latency in neurons by axonal mTOR signaling and the 4E-BP translation repressor"
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6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | K. Andrew White (York University, Canada)
"Global structure of a plus-strand RNA virus genome regulates viral gene expression and replication"
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7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Intrinsic and Innate Immune Response to Viral Infection |
| Discussion Leaders: Joanna Shisler (University of Illinois Champaign/Urbana) and Otto Haller (University of Freiburg, DEU) |
9:00 am - 9:20 am | Ganes Sen (Cleveland Clinic)
"Innate Immune Response to Virus Infection"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Jon Kagan (Harvard Medical School)
"Cell Biological Analysis of Antiviral Innate Immunity"
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9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Blossom Damania (University of North Carolina)
"Interactions of Herpesviruses with the Innate Immune System"
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10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Geoffrey Smith (University of Cambridge, United Kingdom)
"Learning about innate immunity from vaccinia virus evasion strategies"
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11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Stacy Horner (University of Washington)
"The dynamics of innate antiviral immune regulation on the mitochondrial-associated ER membrane (MAM) during RNA virus infection" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Juliet Morrison (Icahn School of Medicine at Mount Sinai)
"Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Jennifer Lumb (Stanford University)
"Systemic identification of interferon antiviral effectors" |
12:10 pm - 12:15 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session II |
5:30 pm - 7:30 pm | Virus Evolution: Finding a Niche |
| Discussion Leader: Colin Parrish (Cornell University) |
5:30 pm - 5:50 pm | Harmit Malik (University of Washington)
"Rules of Engagement: Molecular Insights From Host-Virus Arms Races"
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5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Marco Vignuzzi (Pasteur Institute, France)
"Predicting emergence: Intrahost evolutionary studies identify arbovirus variants with epidemic potential"
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6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Tatyana Golovkina (University of Chicago)
"Role of microbiota in viral infections"
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6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Mark Young (Montana State University)
"Host-virus interactions across all three domains of life"
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7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
9:30 pm | Poster Session II (continued - presenters will be at their posters) |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
9:00 am - 12:30 pm | Viral Pathogenesis |
| Discussion Leaders: Mark Heise (University of North Carolina) and Edward Mocarski (Emory University) |
9:00 am - 9:20 am | Ann Arvin (Stanford University)
"Molecular Mechanisms of Varicella-Zoster Virus Pathogenesis" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Terence Dermody (Vanderbilt University)
"Reovirus invasion of the brain" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Mario Santiago (University of Colorado School of Medicine)
"Innate restriction factor hierarchy in a mouse model of pathogenic retrovirus infection" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:10 am | Benadetta Assetta (Brown University)
"Serotonin 2 receptors facilitate JC polyomavirus entry" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:25 am | Megan Orzalli (Harvard Medical School)
"Mechanisms of IFI16 Sensing of HSV DNA and Restriction of HSV Replication" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Hyelim Cho (Washington University)
"Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive stranded RNA viruses" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Ryan Langlois (Icahn School of Medicine at Mount Sinai)
"Molecular risk mitigation of gain-of-function studies with influenza viruses" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Julie Pfeiffer (UT Southwestern)
"How gut microbes enhance enteric virus infectivity" |
12:10 pm - 12:15 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session II (continued) |
5:30 pm - 7:30 pm | Vaccines and Therapeutics: Development and Deployment |
| Discussion Leader: Kanta Subbarao (NIH) |
5:30 pm - 5:50 pm | Alexandra Trkola (University of Zurich, CHE)
"Shedding light on HIV neutralization"
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5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Ted Pierson (NIH-NIAID)
"Impact of the dynamic structure of flaviviruses on antibody-mediated neutralization: Hitting a moving target"
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6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Pei-Yong Shi (Novartis Institute for Tropical Diseases)
"Targeting viral RNA methylation for therapeutics and vaccine development"
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6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Keynote Presentation: Grant McFadden (University of Florida at Gainesville)
"Oncolytic Virotherapy with Myxoma Virus: The path from the lab bench to the clinic"
|
7:20 pm - 7:30 pm | Discussion |
7:30 pm - 8:00 pm | Closing Reception (LaVeranda Terrace) |
8:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |