SUNDAY |
2:00 pm - 9:00 pm | Arrival and check-in |
6:00 pm | Dinner |
7:30 - 9:30 pm | The Seymour Benzer Symposium on Visual System Development |
| Walter J. Gehring (University of Basel, Switzerland) New Perspectives in Eye Development and Evolution |
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Ulricke Gaul (The Rockefeller University) Glial cell behavior in the Drosophila adult visual system |
| Carol Mason (Columbia University)
Patterning the binocular projection: molecular codes in the optic chiasm and eye |
9:30-11:30 | Reception |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Early eye development |
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Chair: Tom Glaser (University of Michigan) |
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Discussant: Guillermo Oliver (St. Jude Children's Research Hospital) |
| Guillermo Oliver (St.Jude Children's Research Hospital) Analysis of the functional role of Six3 during mouse development |
| Richard A. Lang (Children's Hospital Research Foundation) Genetic pathways regulating lens induction in the mouse |
| Hisato Kondoh (Osaka University) Interplay of transcription factors in early lens development |
10:15 am | Break |
| Francesca Pignoni (Harvard Medical School) The soi gene controls the transition from a pre-proneural state to a proneural state during neuronal development |
| Tom Glaser (University of Michigan) Genetic interactions controlling Rx eyeless phenotype in mice |
| William A. Harris (Cambridge University, UK) Cellular competence plays a role in photoreceptor differentiation in the developing Xenopus retina |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 - 9:30 pm | Photoreceptor Morphogenesis |
| Chair: Claude Desplan (New York University) |
| Discussant: Don Ready (Purdue University) |
| Claude Desplan (New York University) Late photoreceptor differentiation and color vision |
| Donald F. Ready (Purdue University) Drosophila photoreceptor morphogenesis |
| R.H. Masland (Massachusetts General Hospital) Neuronal diversity in the retina |
| Ching-Hwa Sung (Cornell University) Microtubule motor mediated polarized transport in photoreceptors and neurogenesis |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Development of Visual Connections |
| Chair: Carol Mason (Columbia University) |
| Discussant: Ian Meinertzhagen (Dalhousie University) |
| Ian Meinertzhagen (Dalhousie University) & P. Robin Hiesinger (Baylor College, Houston)
Synaptic specification and synapse formation in the Drosophila visual system |
| Paul Garrity (MIT) The axon guidance cue slit and its receptors in the establishment of projection patterns in the Drosophila visual system |
| Tom Clandinin (Stanford University)
Exploring the roles of cadherins in determining photoreceptor target choice in the fly visual system |
10:30 am - 11:00 am | Break |
| Sam Kunes (Harvard University) Eph receptor tyrosine kinase-mediated formation of a topographic map in the Drosophila visual system |
| David Sretavan (UCSF) Mechanisms of retinal axon growth out of the eye to the optic tract |
| Chi-Bin Chien (University of Utah) Genetic dissection of the development of the zebrafish retinotectal projection |
| John Flanagan (Harvard) Ephs and ephrins in targeting and topographic mapping of retinal axons in the thalamus and optic tectum |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:30 pm - 6:00 pm | Business Meeting |
6:00 pm | Dinner |
7:30 - 9:30 pm | Development of cell fates: Signaling molecules |
| Chair: Kevin Moses (Emory University) |
| Discussant: Ross Cagan (Washington University) |
| Ross L. Cagan (Washington University) Patterning and program cell death |
| Ilaria Rebay (Whitehead Institute, MIT) Regulation of photoreceptor cell determination by ubiquitin and endocytosis |
| Nicholas E. Baker (Albert Einstein College of Medicine) A new pathway regulating Notch signalling in developing retina |
| Kwang-W. Choi (Baylor College of Medicine) Lobe Mediates Notch Signaling to Control Domain-Specific Growth in Drosophila Eye Disc |
| Kevin Moses (Emory University) Egfr, Notch and MAP kinase in the developing eye: a tale of two signals |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Development of cell fates: Transcription factors |
| Chair: Connie Cepko (Harvard University) |
| Discussant: Andrew Jarman (Cambridge University) |
| Connie Cepko (Harvard University) Genomics Approaches to Photoreceptor Development and Disease |
| Ryoichiro Kageyama (Kyoto University) Roles of bHLH and homeobox genes in retinal cell type specification |
| Anand Swaroop (University of Michigan) Molecular insights into final stages of mammalian rod differentiation: Role of Nrl and other transcription factors |
10:30 am - 11:00 am | Break |
| Andrew Jarman (University of Edinburgh) bHLH transcription factor specificity in Drosophila |
| Monica Vetter (University of Utah) Analysis of regulatory elements driving Xath5 expression in the developing Xenopus retina |
| Lydia Michaut (Biozentrum, Basel University) Characterisation of novel genes involved in Drosophila eye development using Affymetrix GeneChip technology |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:30 - 9:30 pm | Evolution and Eye Development |
| Chair: Pamela Raymond (University of Michigan) |
| Discussant: Volker Hartenstein (UCLA) |
| Jochen Wittbrodt (EMBL) Of fish and worms - new angles on eye development and evolution |
| Volker Hartenstein (UCLA) Conserved topologies and signaling pathways in visual system development |
| Pamela A. Raymond (University of Michigan) Patterning the retina: moving waves and mosaic arrays |
| Maureen Neitz (Medical College of Wisconsin) Expression of L and M cone opsin genes and evolution of trichromatic color vision in primates |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Development of cell fates: Signaling molecules II |
| Chair: Utpal Banerjee (UCLA) |
| Discussant: Jessica Treisman (New York University) |
| Utpal Banerjee (UCLA) Parallel and sequential signaling in cell fate determination |
| Jeffrey Lee, Florence Janody, Aude Benlali, Zara Martirosyan & Jessica Treisman (NYU) Novel genes that affect Hedgehog function in eye disc patterning |
| Xian-Jie Yang (UCLA) Regulation of early retinal progenitor fates by secreted molecules |
10:30 am - 11:00 am | Break |
| Yasushi Hiromi (National Institute of Genetics, Japan) The role of FGF signaling in Drosophila eye development |
| Jarema Malicki (Harvard Medical School) Cell-cell interactions in zebrafish retinal neurogenesis |
| Barry Dickson (IMP, Vienna) Matching cell fates and positions as the eye connects to the brain |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
6:00 pm | Dinner |
7:30 - 9:30 pm | New waves in visual system development |
| Chair: Monica Vetter (University of Utah) |
| Discussant: Marek Mlodzik (Mount Sinai School of Medicine) |
| Benjamin J. Frankfort & Graeme Mardon (Baylor College of Medicine) The function of the transcription factor, Senseless, in Drosophila eye development |
| Marek Mlodzik (Mt. Sinai School of Medicine) Frizzled/planar polarity signaling and establishment of ommatidial polarity |
| Eric Green (University of Utah) Chx10 regulates cell number through interactions with G1 phase cell cycle proteins |
| Dorothea Schulte (Max-Planck-Institut, Frankfurt, Germany)
Common and Unique Mechanisms Controlling Photoreceptor Pattern and Retinotopic Order in the Chick Retina |
| Andrew Zelhof (UCSD) short sighted is required for phototransduction and rhabdomere morphogenesis |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |