SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Check-in Desk Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | FRONTIERS IN VISUAL SYSTEM RESEARCH |
7:40 pm - 7:50 pm | Welcome and Introductions: Monica Vetter, Chair (U of Utah); Helen McNeill, Vice Chair (Samuel Lunenfeld Research Institute) |
7:50 pm - 8:20 pm | Robin Ali (University College London) "Strategies for repairing the retina using cell transplantation" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:05 pm | Dennis O’Leary (The Salk Institute) "Mechanisms regulating development and refinement of retinotopic maps" |
9:05 pm - 9:20 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | STEM CELLS, PROGENITORS AND PROLIFERATION |
| Discussion Leader: Tom Reh (University of Washington) |
9:00 am - 9:20 am | Nick Baker (Albert Einstein College of Medicine) "Prelude to neurogenesis: how other HLH genes set the stage for proneural bHLH function" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Michel Cayouette (IRCM, Montreal) "Asymmetric cell divisions in the developing mouse retina" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break / Group Photo |
10:30 am - 10:40 am | Carla Lopes (CSIC, Spain) "The shape of eyes to come: coupling fate and proliferation through the interplay between Homothorax and Dpp" |
10:40 am - 10:45 am | Discussion |
10:45 am - 10:55 am | Kiyo Sakagami (Jules Stein, UCLA) "Essential roles of PTEN/PI3K signaling in proper retinal network formation" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Rod Bremner (Toronto Western Research Institute) "Cell cycle regulators and retinal development" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Richard Mann (Columbia University) "Making enough cells: control of progenitor domain proliferation in the fly eye" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Bill Harris (Cambridge University) "Are there determinative lineages in the retina?" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | EARLY EYE DEVELOPMENT AND EVOLUTION |
| Discussion Leader: Francesca Pignoni (Upstate Medical University) |
5:30 pm - 5:50 pm | Michael Zuber (Upstate Medical University) "Vertebrate eye field specification" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Justin Kumar (Indiana University) "Tissue Specification is Linked to Cell Proliferation in the Developing Retina" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Julian Partridge (University of Bristol) "Unique visual adaptations in deep sea vertebrates" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Detlev Arendt (EMBL Heidelberg) "The division of labour model of eye evolution" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | DEVELOPMENT OF OCULAR TISSUES |
| Discussion Leader: Richard Lang (Cincinnati Children's Research Foundation) |
9:00 am - 9:20 am | Brian Link (Medical College of Wisconsin) "Apical membrane and the regulation of neurogenesis in retinal neuroepithelia" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Ross Cagan (Mount Sinai School of Medicine) "Assembling an organ: lessons from the fly pupal eye" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:40 am | Salil Lachke (Harvard) "TDRD7 encodes an RNA granule component that functions in mammalian lens development" |
10:40 am - 10:45 am | Discussion |
10:45 am - 10:55 am | Joe Brzezinski (University of Washington) "Blimp1 regulates photoreceptor versus bipolar cell fate choice during retinal development" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Tiffany Cook (Cincinnati Children's Hospital Medical Center) "Transcriptional control of cell type specification in the Drosophila lens" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Tom Glaser (University of Michigan) "Novel mutations affecting human retinal neurogenesis" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Holger Gerhardt (London Research Institute) "Angiogenesis - a team work coordinated by Notch" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | GENE REGULATION AND EYE DEVELOPMENT |
| Discussion Leader: Graeme Mardon (Baylor College of Medicine) |
5:30 pm - 5:50 pm | Richard Carthew (Northwestern University) "Making eye development robust: a microRNA nibbles at the edges" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Ales Cvekl (Albert Einstein College of Medicine) "Reconstruction of Pax6-dependent networks in mammalian eye development" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Ilaria Rebay (University of Chicago) "Cytoplasmic functions of the Eyes absent phosphatase" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Shiming Chen (Washington University) "Crx and its interacting transcription factors in regulating target gene chromatin configurations during photoreceptor development and disease" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CELL SIGNALING AND MORPHOGENESIS |
| Discussion Leader: Valerie Wallace (Ottawa Hospital Research Institute) |
9:00 am - 9:20 am | Marek Mlodzik (Mount Sinai School of Medicine) "Wnt-Frizzled-PCP signaling in photoreceptor R3/R4 specification in Drosophila" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Sabine Fuhrmann (University of Utah) "Extracellular factors regulating development of the retinal pigment epithelium" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:40 am | Kristen Kwan (University of Utah) "Morphogenesis, cell motility and polarity in the developing vertebrate eye" |
10:40 am - 10:45 am | Discussion |
10:45 am - 10:55 am | Onkar Dhande (Yale University) "Adenylate Cyclase 1 is Required for Activity Dependent Retinocollicular Map Refinement" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Paola Bovolenta (Instituto Cajal, CSIC) "Dual role of Secreted Frizzled Related Proteins in eye morphogenesis" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Franck Pichaud (University College, London) "Photoreceptor morphogenesis and apico-basal polarity remodeling" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Juan Ramon Martinez-Morales (CSIC-Universidad Pablo de Olavide) "Cellular and molecular mechanisms of optic cup morphogenesis" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | DEVELOPMENT OF PHOTOSENSITIVE CELLS |
| Discussion Leader: Pamela Raymond (University of Michigan) |
5:30 pm - 5:50 pm | Steven Britt (University of Colorado, Denver) "Drosophila photoreceptor cell fate is regulated by nephrin-like immunoglobulin superfamily (IgSF) members" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | King-Wai Yau (Johns Hopkins University) "Signaling by Melanopsin Retinal Ganglion Cells" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Ulrich Tepass (University of Toronto) "Crumbs function and regulation in Drosophila photoreceptor morphogenesis" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Steven Reppert (U Massachusetts, Worcester) "Photosensory transduction in migrating monarch butterflies" |
7:20 pm - 7:30 pm | Discussion |
7:30 pm - 8:00 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
8:00 pm | Dinner |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CONNECTIVITY IN THE VISUAL SYSTEM |
| Discussion Leader: Iris Salecker (National Institute for Medical Research, London) |
9:00 am - 9:20 am | Christine Holt (University of Cambridge) "Local translation and degradation regulate guidance and modeling of retinotectal terminals" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Robin Hiesinger (UT Southwestern Medical Center) "A degradation pathway required for synapse specification and maintenance in the Drosophila visual system" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Claude Desplan (New York University) "Development of the Drosophila color visual system" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | David Feldheim (UC Santa Cruz) "Mechanisms of visual map alignment" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Chi-Hon Lee (National Institutes of Health) "Autocrine and paracrine TGF-beta signaling coordinates the formation of synaptic connections between photoreceptors and amacrine cells in Drosophila" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Rachel Wong (University of Washington) "Circuit assembly in the developing vertebrate retina" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | RETINAL DEVELOPMENT AND DISEASE |
| Discussion Leader: Tom Glaser (University of Michigan) |
5:30 pm - 5:50 pm | Michael Dyer (St. Jude Children's Research Hospital) "Bridging the gap between development and disease in the retina" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Utpal Banerjee (UCLA) "Metabolic Control of Cell Proliferation and Fate" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Kang Zhang (University of California San Diego) "Genetics and stem cell based therapy for age-related macular degeneration" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Zhigang He (Children's Hospital - Harvard) "New strategies of promoting optic nerve regeneration" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |