Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Corneal Stem Cells and Neuronal Circuits
Discussion Leaders: Graeme Mardon (Baylor College of Medicine, USA) and Seth Blackshaw (Johns Hopkins University School of Medicine, USA)
7:40 pm - 8:25 pm
Rachel Wong (University of Washington, USA)
"Retinal Circuit Assembly and Reassembly"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:20 pm
Julie Daniels (UCL Institute of Ophthalmology, United Kingdom)
"Corneal Stem Cells: From Niche to Therapy"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
From Retinal Patterning to Cell Fate Specification
Discussion Leader: Muriel Perron (CNRS, France)
9:00 am - 9:25 am
Nadean Brown (University of California, Davis, USA)
"Notch Signaling During Very Early Eye Patterning"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
Kristen Kwan (University of Utah, USA)
"Morphogenetic Mechanisms Regulating Vertebrate Optic Cup Formation"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
James Fadool (Florida State University, USA)
"Shifting the Photoreceptor Landscape Through Genetic Interactions"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Ruth Johnson (Wesleyan University, USA)
"Transforming the Drosophila Pupal Eye from Organized Chaos into a Perfectly Patterned Neuroepithelium"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Caren Norden (Max Planck Institute of Molecular Cell Biology and Genetics, Germany)
"3D Decomposition of Retinal Neuroepithelial Growth Reveals that Cell Non-Autonomous Actin Redistribution Leads to Isotropic Shape Scaling"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:25 pm
Ordan Lehmann (University of Alberta, Canada)
"The Forkhead Transcription Factor Foxc1 Controls Cilia Structure and Function"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
Organizer: Ruth Johnson (Wesleyan University, USA)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Axonal Guidance and Synaptogenesis
Discussion Leader: Iris Salecker (The Francis Crick Institute, United Kingdom)
6:00 pm - 6:25 pm
Holger Apitz (The Francis Crick Institute, United Kingdom)
"Generation of Layer-Specific Motion-Direction Selective Neurons in Drosophila "
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:55 pm
Alex Kolodkin (Johns Hopkins School of Medicine / Howard Hughes Medical Institute, USA)
"Molecular Mechanisms Underlying Visual System Connectivity"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:25 pm
Carol Mason (Columbia University, USA)
"Genesis, Guidance, and Pathway Organization of Ipsi- vs Contralateral Retinal Ganglion Cells"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:55 pm
Andrew Huberman (Stanford University, USA)
"Merging Sensation and Emotion in the Visual System: Fear, Risk and Action"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Central Visual System Development
Discussion Leader: Marek Mlodzik (Icahn School of Medicine at Mount Sinai, USA)
9:00 am - 9:25 am
Herwig Baier (Max Planck Institute of Neurobiology, Germany)
"Dissecting and Assembling the Retinal Projectome"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
Michael Crair (Yale University, USA)
"Spontaneous Activity in Visual Circuit Development"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Elly Nedivi (Massachusetts Institute of Technology, USA)
"Monitoring Synapse Assembly/Disassembly In Vivo During Visual Cortex Development"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Alain Prochiantz (Collège de France, France)
"Developmental Regulation of Visual Cortex Plasticity by Non-Cell Autonomous Otx2"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Jean-Marc Matter (University of Geneva, Switzerland)
"How the Developing Pigeon Optic Tectum Adapts to the Late and Massive Arrival of Optic Nerve Axons?"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:25 pm
Claude Desplan (New York University, USA)
"Development of the Fly Motion Vision System"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Retinal Regeneration
Discussion Leader: Katia Del Rio-Tsonis (Miami University, USA)
6:00 pm - 6:25 pm
Zhigang He (Harvard Medical School, USA)
"New Strategies of Promoting Optic Nerve Regeneration"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:55 pm
Valerie Wallace (Toronto Western Research Institute, Canada)
"Investigating Donor-Host Photoreceptor Interactions in Grafted Retinas"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:25 pm
David Hyde (University of Notre Dame, USA)
"Gene Expression and Chromatin Changes During Zebrafish Muller Glia Reprogramming Under Different Damage Paradigms"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:55 pm
Muriel Perron (CNRS, France)
"The Hippo/Yap Signaling Pathway and Retinal Regeneration from Müller Glia"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Non-Neuronal Development
Discussion Leader: Ruth Ashery-Padan (Tel Aviv University, Israel)
9:00 am - 9:25 am
Adi Inbal (The Hebrew University of Jerusalem, Israel)
"Mechanisms Disrupting Lens Epithelium Fate"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
Hisato Kondoh (Kyoto Sangyo University, Japan)
"Mechanisms Underlying Lens Transdifferentiation from Neural Retina and Pituitary"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Peter Lwigale (Rice University, USA)
"Corneal Development: New Insights from Periocular Neural Crest Differentiation and Embryonic Corneal Regeneration"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Brenda Bohnsack (University of Michigan, USA)
"Molecular Distinction of Ocular Neural Crest Cells"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Tiffany Cook (Wayne State University School of Medicine, USA)
"Dissecting Conserved Retinal Support Functions"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:25 pm
Ross Poche (Baylor College of Medicine, USA)
"Hippo Pathway Regulation of Müller Glial Cell-Mediated Retinal Regeneration"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Unconventional Photoreceptors
Discussion Leader: Andrew Huberman (Stanford University, USA)
6:00 pm - 6:25 pm
Ethan Buhr (University of Washington, USA)
"The Influence of Non-Canonical Opsins on Circadian Rhythms in the Retina"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:55 pm
Anna Matynia (University of California, Los Angeles, USA)
"Seeing Is Not Perceiving: Biology of Melanopsin-Containing Corneal Sensory Nerves"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:25 pm
Harold Burgess (National Institute of Child Health and Human Development, NIH, USA)
"Deep Brain Photoreceptors Control Light-Search Strategy in Zebrafish"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:55 pm
Richard Lang (Cincinnati Children's Research Foundation, USA)
"Encephalopsin (OPN3) and Neuropsin (OPN5) Regulate Visual System Development and Systemic Homeostasis in Mice"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Genomics of Visual System Development
Discussion Leader: Rui Chen (Baylor College of Medicine, USA)
9:00 am - 9:25 am
Ruth Ashery-Padan (Tel Aviv University, Israel)
"Transcriptional Networks Regulating the Transitions from Multipotent Progenitors to Terminally Differentiated Cells Types of the Eye"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
Shiming Chen (Washington University, USA)
"Meta-Analysis of Epigenetic Remodeling Reveals CRX's Mechanism if Action in Photoreceptor Development"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Michael Dyer (St. Jude Children's Research Hospital, USA)
"Cellular Pliancy in Retinal Development and Disease"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Ales Cvekl (Albert Einstein College of Medicine, USA)
"Transcriptional Dynamics During Lens Cell Differentiation and Novel Insights in Denucleation Process"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Robert Hufnagel (National Eye Institute, NIH, USA)
"Predicting Causality for Neuro-Ocular Disorders by Gene Constraint"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:25 pm
Jeremy Kay (Duke University, USA)
"Alternative Splicing and Promoter Use Are Major Determinants of the Cell-Surface Molecular Repertoire in Developing Retina"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Emerging Model Systems
Discussion Leader: Markus Friedrich (Wayne State University, USA)
6:00 pm - 6:25 pm
Robert Johnston (Johns Hopkins University, USA)
"Control of Cone Subtype Specification in Human Retinal Organoids"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:55 pm
Kristin Tessmar-Raible (Max F. Perutz Laboratories / University of Vienna, Austria)
"The Impact of Sun and Moon on the Behavior and Physiology of Animals"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:25 pm
Bret Pearson (Hospital for Sick Children, University of Toronto, Canada)
"Deconstructing Neural Regeneration: Flatworming Our Way Forward"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:55 pm
Brigitte Schoenemann (University of Cologne, Germany)
"Visual Systems Some Hundred Million Years Ago"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure