Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Frontiers in Visual Systems Development and Disease
Discussion Leader: Nadean Brown (University of California, Davis, United States)
7:40 pm - 8:25 pm
Thomas Reh (University of Washington, United States)
"Cell Fate Engineering for Retinal Repair in Mammals"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:20 pm
Masayo Takahashi (Kobe Eye Center, Japan)
"Good Neighbors: Cell-Cell Signaling in Retinal Sheet Transplantation"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
From Retinal Patterning to Cell Fate Specification
Discussion Leaders: Ann Morris (University of Kentucky, United States)
9:00 am - 9:25 am
Justin Kumar (Indiana University, United States)
"The Timing of Cell Fate Decisions is Crucial for Initiating Pattern Formation"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
Robert Johnston (Johns Hopkins University, United States)
"Stochastic Cell Fate Specification in the Fly Eye"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Vilaiwan Fernandes (University College London, United Kingdom)
"Diversifying Neurons and Setting their Numbers in Drosophila"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Kristen Kwan (University of Utah, United States)
"Retina-Lens Detachment: a Matrix-Mediated Step of Vertebrate Eye Development"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Monica Vetter (University of Utah, United States)
"Regulation of Temporal Patterning of Progenitors Through Jarid2-Mediated Polycomb Repression"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Amit Singh (University of Dayton, United States)
"JAK/STAT Signaling Regulates Defective Proventriculus (Dve) to Determine Dorso-Ventral Patterning in Drosophila Eye"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Katarzyna Hussey (Johns Hopkins University, United States)
"Foveolar cone subtype patterning in human retinal organoids"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Monica Vetter (University of Utah, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Genome-Wide Approaches for Studying Visual Development
Discussion Leader: Michael Dyer (St. Jude Children's Research Hospital, United States)
7:30 pm - 7:55 pm
Xin Li (University of Illinois Urbana-Champaign, United States)
"Temporal Patterning of Drosophila Medulla Neuroblasts at Single-Cell Resolution"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
Brian Clark (Washington University School of Medicine in St. Louis, United States)
"Understanding Cis-Regulatory Sequence use Across Retinal Development"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
Rui Chen (Baylor College of Medicine, United States)
"Single Cell Spatial Atlas of the Retina"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Xiuqian Mu (University at Buffalo, United States)
"Key Transcription Factors Interact with and Influence the Epigenetic Landscape to Promote Retinal Ganglion Cell Genesis"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Feng Tian (Boston Children's Hospital, United States)
"Transcriptional Programs of Retinal Ganglion Cell Survival and Axon Regeneration"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Building, Remodeling and Repairing Retinal Circuitry
Discussion Leader: Jeremy Kay (Duke University, United States)
9:00 am - 9:25 am
Peter Robin Hiesinger (Free University of Berlin, Germany)
"Target-Independent Visual Map Formation in Drosophila"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
Melanie Samuel (Baylor College of Medicine, United States)
"Neural-Immune Interactions in the Developing Retina"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Iris Salecker (Institut de Biologie de l'Ecole Normale Supérieure, France)
"A Dialog with Neurons Helps Visual System Astrocytes to find Their Shape"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Group Photo / Coffee Break
11:00 am - 11:25 am
Julie Lefebvre (Hospital for Sick Children and University of Toronto, Canada)
"Dendrite Dynamics and Growth Rules that Specify Retinal Wiring"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Alain Chedotal (Institut de la Vision, France)
"3D Analysis of Human Eye Development"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Kevin Wright (Oregon Health & Science University, United States)
"Molecular Mechanisms of Amacrine Cell Specification and Maturation"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Caroline Dumas (University of Vermont, United States)
"Functional Analysis of Reverse Sema6A Signaling in Zebrafish Retinal Development"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Non-Neuronal Cells and Tissues
Discussion Leader: Ruth Ashery-Padan (Tel Aviv University, Israel)
7:30 pm - 8:00 pm
Jin Woo Kim (Korea Advanced Institute of Science and Technology (KAIST), South Korea)
"Edge vs. Border: Divergent Cell Fate Determination in the Ciliary Margin"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
Ryan MacDonald (University College London, United Kingdom)
"Cellular and Molecular Mechanisms Regulating Muller Glial Morphogenesis"
8:45 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Revathi Balasubramanian (Columbia University, United States)
"A Single Cell Analysis of Schlemm's Canal Development"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Wenjun Yan (Harvard University, United States)
"A Cell Atlas of the Human Eye"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Central Visual Development and Sensory Integration
Discussion Leader: David Feldheim (University of California, Santa Cruz, United States)
9:00 am - 9:25 am
Chi-hon Lee (Academia Sinica, Taiwan)
"Routing Dendrites in Drosophila Visual Neurons"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
Xin Duan (University of California, San Francisco, United States)
"Trans-Seq: Translating Transcriptomics to Connectomics at Retinotectal Synapses"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Samer Hattar (National Institute of Mental Health, NIH, United States)
"Light Modulates the Function of the Prefrontal Cortex via a Retinal Pathway"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Takao Hensch (Harvard University, United States)
"Fast-Spiking GABA Circuit Control of Visual Cortical Plasticity"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Karthik Shekhar (University of California, Berkeley, United States)
"Vision-Dependent Specification of Cell Types and Function in the Developing Cortex"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Nicholas Tran (Baylor College of Medicine, United States)
"Identifying Gene Targets for RGC Neuroprotection and Axon Regeneration using scRNA-seq"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Development and Dysfunction of the Primate Retina
Discussion Leaders: Tom Glaser (UC-Davis, United States)
7:30 pm - 7:55 pm
Rod Bremner (Lunenfeld Tanenbaum Research Institute, Canada)
"Human Cone Photoreceptor Specification"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
Raunak Sinha (University of Wisconsin Madison, United States)
"Functional Development of Photoreceptors in Human Retinal Organoids"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
Susana da Silva (University of Pittsburgh School of Medicine, United States)
"How to Make a Fovea"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Rajesh Rao (University of Michigan, United States)
"Mechanistic Insights into the Function of PRDM13 in North Carolina Macular Dystrophy"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Brian Brooks (National Eye Institute, United States)
"Modeling of Human Oculocutaneous Albinism Using iPSC-derived RPE"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Cellular Regeneration and Stem Cells
Discussion Leader: Michel Cayouette (Montreal Clinical Research Institute (IRCM), Canada)
9:00 am - 9:25 am
Katia Del Rio-Tsonis (Miami University, United States)
"Inflammation Drives Newt Lens Regeneration"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
Jeff Mumm (Johns Hopkins University, United States)
"An Ascl1a-Independent Pathway to Retinal Ganglion Cell Regeneration in Zebrafish"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Mike Karl (German Center for Neurodegenerative Diseases (DZNE), Germany)
"Retinal Pathology Models in Organoids for Regeneration Research"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Kapil Bharti (National Institutes of Health, United States)
"Understanding Human RPE Heterogeneity using iPS Cells"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Carol Schuurmans (Sunnybrook Research Institute, Canada)
"Targeting Pten to Unlock the Regenerative Potential of the Mammalian Retina"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Daniel Murphy (Washington University School of Medicine, United States)
"Genetic Reprogramming via Acute Nr2e3 Knockout Prevents Photoreceptor Degeneration"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Ryoji Amamoto (Harvard Medical School, United States)
"Retinoic Acid Signaling Mediates Peripheral Cone Photoreceptor Survival in a Mouse Model of Retina Degeneration"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Emerging Systems for Studying Visual Development
Discussion Leader: Tiffany Cook (Wayne State University School of Medicine, United States)
7:30 pm - 8:00 pm
Kristen Koenig (Harvard University, United States)
"Early Neurogenesis in the Cephalopod Retina"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
Wei Li (NIH, United States)
"Cone Development in Rod- and Cone-Dominant Species"
8:45 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Yohei Ogawa (Washington University School of Medicine, United States)
"Deep Evolutionary Conservation of Retinal Cis-Regulatory Codes Despite Extensive Enhancer Turnover"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Shubham Rathore (University of Cincinnati, United States)
"Probing Conserved Roles of Cut in the Development and Function of Insect Compound Eyes"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure