Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Frontiers in Neuronal Cell Fate and Connectivity
7:40 pm - 8:25 pm
"Deterministic and Stochastic Specification of Neural Fates in the Drosophila Visual System"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:20 pm
"Novel Mechanisms of Neurogenesis and Neural Repair"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Retinal Patterning and Cell Fate Specification
9:00 am - 9:20 am
"Role of the Circadian Clock in Retinal Neurovascular Development"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
"Tiling Mechanisms of the Drosophila Compound Eye"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
"Blood Borne ATP Regulates CNS Neuron Polarity"
10:10 am - 10:15 am
Discussion
10:15 am - 10:30 am
"Investigating the Photoreceptor Nuclear Migration Defect in RP2 Mice"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Sonic Hedgehog in Optic Cup Patterning"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
"A Non-Canonical Planar Cell Polarity Pathway Triggered by Light Organizes Cone Photoreceptors in the Mouse Retina"
11:50 am - 11:55 am
Discussion
11:55 am - 12:10 pm
"Postnatal Expression of Developmental Transcription Factors Directs Generation of Induced Retinal Ganglion Cells"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Cis-Regulatory Control of Retinal Ganglion Cell Genesis and Axonogenesis"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Non-Neuronal Cells and Tissues
6:00 pm - 6:20 pm
"Investigation of Effects of Hippo Pathway Modulation on RPE Injury"
6:20 pm - 6:25 pm
Discussion
6:25 pm - 6:45 pm
"Eyes on Stem Cells: Deciphering Limbal Stem Cell Dynamics, Regulation and Repair"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:10 pm
"A Fly's Eye View of Corneal Development"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:35 pm
"Signaling from Periocular Neural Crest Cells Regulates Neurovascular Patterning in the Anterior Eye During Development"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
"Retinal Coloboma in Yapnl13 Mutants is Due to Reduced RPE Contractility and is Enhanced by Mutations in Extracellular Matrix and Other Genes Associated with Congenital Defects of Eye Formation"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Building, Remodelling and Repairing Retinal Circuity
9:00 am - 9:20 am
"Bystander Effects and Inflammatory Responses in Inherited Retinal Degeneration"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
"A Role for Retinal Waves in the Establishment of Direction Selective Circuits in the Retina"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
"The Synaptic Pathways Providing Visual Inputs to the Navigation Center in the Drosophila Central Brain"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Pull to Push: Filopodium-Mediated Homotypic Recognition Regulates Zebrafish Cone Mosaic"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Molecular Mechanisms of Synapse Development"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Molecular Principles Guiding Synaptic Connectivity of Photoreceptors"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Experience-Dependent Plasticity in the Retina"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Concurrent Temporal Patterning of Neural Progenitors in the Fly Visual System"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Central Visual Development and Sensory Integration
6:00 pm - 6:25 pm
"How Does Functional Diversity Emerge Across Visual Processing Pathways?"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:55 pm
"Non-Canonical Roles of Oligodendrocyte Precursor Cells in Visual Circuit Refinement and Remodeling"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:25 pm
"How the Form and Function of Retino-Tectal Circuitry is Shaped by Oligodendrocyte Precursor Cells"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Glutamatergic Neuronal Activity Regulates Angiogenesis and Blood-Retinal Barrier Maturation via Norrin/Beta-Catenin Signaling"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Single-Cell Multi-Omic Dissection of Experience-Dependent Cell Type Development in Mouse Visual Cortex"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Genome Wide Approaches in Retinal Development Disease and Aging
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Astrocyte-Microglia Signaling Controls Developmental Synapse Remodeling in the Visual Cortex"
9:25 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Gene Regulatory Networks Controlling Vertebrate Retinal Aging"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Protecting the Retina from Diabetes-Induced Damage"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Age-Dependent Epigenetic Changes in the Retina Alter the CIrcadian Transcriptome"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"A Mechanism that Stabilizes Vitamin A-Deficient and Rhodopsin-Mutant Drosophila Photoreceptors"
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Non-Coding Mechanisms of Retinal Development and Disease"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Coordinating Stereotyped and Stochastic Pattern in the Drosophila Eye"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Development and Dysfunction of the Primate Retina
6:00 pm - 6:20 pm
"Molecular Characterization of Foveal and Peripheral Cell Types in Human and Non-Human Primate Retinas: From Development to Evolution"
6:20 pm - 6:25 pm
Discussion
6:25 pm - 6:45 pm
"Spatiotemporal Single Cell Analyses Reveal a Transient Population of Retinal Progenitor Cells in the Ciliary Margin of Developing Human Retina"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:10 pm
"Homeotic Hotspot in the Human Genome - An Enhancer Trap with Eye and Brain Phenotypes"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:35 pm
"Retinal Ganglion Cells and Glial Interactions in a Human Pluripotent Stem Cell Model of Neurodegeneration and Neuroinflammation"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
"Peripheral Immune Invasion Suppresses Mammalian Retinal Regeneration"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Emerging Systems for Studying Visual Development
9:00 am - 9:10 am
"Planarians as an Emerging Model for Visual System Regeneration"
9:10 am - 9:15 am
Discussion
9:15 am - 9:35 am
"Conservation of Retinal Cis -Regulatory Codes Over Half a Billion Years"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Molecular Evolution of Reptile Photoreceptors"
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
"See You in the Dark: Vision in Deep-Sea Fishes and Their Shallow-Water Larvae"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"A Tale of Two Visual Systems: Parallel Structural and Functional Pathways for Motion Guided and Feature Guided Behaviors"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"The Rime of Ancient Eyes: Parallel, Convergent, and Path Dependent Evolution"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Single-Nucleus RNA Sequencing of the Shark Retina: Insights on the Evolution of Postnatal Neurogenesis"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Genetically Engineered Opossum, a Novel Non-Rodent Mammalian Model to Study the Pathogenesis of Inherited Retinal Diseases"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cellular Regeneration, Repair and Stem Cells
6:00 pm - 6:20 pm
"Transplantation of Human Photoreceptors into Mouse Models of Retinal Degeneration"
6:20 pm - 6:25 pm
Discussion
6:25 pm - 6:45 pm
"M/L Cone Production, Characterization and Enrichment from Human Pluripotent Stem Cells"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:10 pm
"The Ambivalent Role of Inflammation in Retinal Regeneration"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:35 pm
"Exploring Retinal Cell Reprogramming Using Human Pluripotent Stem Cells"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
"Donor Photoreceptor Connectivity in Vivo"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure