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Wnt Signaling (GRS)

Gordon Research Seminar

Wnt Signaling in Development, Disease and Tissue Regeneration

July 29 - 30, 2023
Chairs and
Rey Don Jaime Grand Hotel
Avinguda de l'Hotel
Castelldefels, Barcelona, Spain
 Venue and Travel Information

Conference Description

The Wnt Signaling GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

The focus of this meeting is to gain deeper understanding of how the Wnt signaling pathway regulates fundamental processes such as development, tissue homeostasis and regeneration.

Related Meeting

This GRS will be held in conjunction with the "Wnt Signaling" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: An Updated Overview of Wnt Signaling
Discussion Leader:
3:15 pm - 3:50 pm
"An Updated Overview of Wnt Signaling"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Wnt Signaling: From Mechanisms to Therapeutics
Discussion Leader:
5:30 pm - 5:40 pm
"Investigating ß-Cat-Responsive Transcription (CRT) Inhibitors to Remodel Tumour-Immune Microenvironment in Colorectal Cancer"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
"Polarity and Proximity: BioID-Based Mapping of Wnt/PCP Interactome and its Functional Analysis"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:10 pm
"Regulators of Dvl2 Localization to Wnt-Dependent Biomolecular Condensates"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
"ETC-159, an Upstream Wnt Inhibitor, Induces Tumour Necrosis via Modulation of Angiogenesis in Osteosarcoma"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"WNT7B Drives a Program for Pancreatic Cancer Subtype Switching and Progression"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"Tumor Selective WNT Suppression in Colorectal Cancer"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"Identification of Semaphorin Receptors as Novel WNT Pathway Antagonists"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"An Induced Protein Proximity Screen to Identify Regulators of Wnt Signaling in Colorectal Cancer"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Wnt Signaling in Stem Cell Biology and Regenerative Medicine
Discussion Leader:
9:00 am - 9:10 am
"CRISPR Base Editor Scanning Marks Essential Factors for Tankyrase Activity"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"The Time-Resolved Genomic Impact of Wnt/ß-Catenin Signalling"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Dynamic Cooperation of Heparan Sulfate Proteoglycans with Wnt11 and Core PCP Components in the Regulation of Planar Cell Polarity"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Wnt Signaling in Membrane Trafficking and Cell Adhesion"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Robinow Syndrome Associated Frizzled2 Mutations Alter Skeletogenesis and WNT Pathway in the Face"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Single Cell Transcriptomics identifies a WNT7A-FZD5 Signaling Axis that Maintains Fallopian Tube Stem Cells in Patient-Derived Organoids"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Dvl Specificity Required for Hematopoietic Stem Cell Development"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"The Planar Polarity Regulator Casein Kinase Ie is Asymmetrically Distributed within Cells Colocalising With its Molecular Target Dishevelled"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: How to Have a Successful Career in Research
Discussion Leader:
1:30 pm - 2:30 pm
Panel Discussion
How to Have a Successful Career in Research
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes

Contributors

National Institutes of Health (NIH)
AMSBIO (AMS Biotechnology)

Research reported in this publication was supported by the National Institutes of Health under Award Number R13HD105309. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Wnt Signaling
Additional Fee Info

Wnt Signaling
June 22 - 27, 2025


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