| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chairs (Helge Jochens/Aram Panay) |
| 3:45 pm - 4:30 pm | Keynote Address: Challenges and Opportunities in Microbial Biosynthesis |
| 3:45 pm - 4:15 pm | Kristala Jones-Prather (MIT, USA)
"Challenges and Opportunities in Microbial Biosynthesis" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 8:30 pm | Biocatalysts with Novel Function |
| Discussion Leaders: Hans-Peter Mayer (Lonza AG, Switzerland) and Lucy Chappell (University of Leeds, UK) |
| 7:30 pm - 7:50 pm | Matthew Merski (UCSF, USA)
"Engineering a Model Protein Cavity to Catalyze the Kemp Elimination" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Ashley Daugherty (Emory University, USA)
"Circular Permutation of Old Yellow Enzyme: In Vitro Characterization of a Complete Synthetic Library" |
| 8.20 pm - 8.30 pm | Discussion |
| 8:30 pm - 9:30 pm | Discussion Panel: Careers in Biocatalysis |
| Moderator: Stefan Lutz (Emory University, USA) |
| Panelists: Kristala Jones-Prather (MIT, USA), Gjalt Huisman (Codexis, USA) and Catherine Goodman (Senior Editor, Nat. Chem. Biol.) |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Green Chemistry - Biocatalysts at Work |
| Discussion Leaders: Stefan Lutz (Emory University, USA) and Marta Pontini (University of Manchester, UK) |
| 9:00 am - 9:20 am | Michael Fink (Vienna Institute of Technology, Austria)
"A Chemo-Enzymatic Cascade Process for Single-Operation Synthesis of Chiral Aroma Lactones" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Nadine Ladkau (Technical University Dortmund, Germany)
"Specific Terminal Oxy- and Aminofunctionalization of Dodecanoic Acid Methyl Ester Coupled in a Single Whole-Cell Catalyst" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Daniela Quaglia (University College Dublin, Ireland)
"A Classic Oxidoreductase with a Modern Twist" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Maria Villegas Torres (University College London, UK)
"Design and Characterisation of a Multi-modular Enzymatic Expression System for De Novo Synthesis of Chiral Amino Alcohols" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:45 pm | Putting the Rational back into Biocatalysis |
| Discussion Leaders: Gjalt Huisman (Codexis, USA) and Hein J. Wijma (University of Groningen, Netherlands) |
| 1:30 pm - 1:50 pm | Sebastian Bartsch (University of Groningen, Netherlands)
"Redesign of a Phenylalanine Aminomutase into a beta-Phenylalanine Ammonia Lyase" |
| 1:50 pm - 1:55 pm | Discussion |
| 1:55 pm - 2:15 pm | Sabrina Kille (Max-Planck Institute für Kohleforschung, Germany)
"Find your Hit faster" |
| 2:15 pm - 2:20 pm | Discussion |
| 2:20 pm - 2:40 pm | Panwajee Payongsri (University College London, UK)
"Directed Evolution of Transketolase to Access Aromatic Dihydroxy Ketones Towards the Synthesis of Novel Antibiotics" |
| 2:40 pm - 2:45 pm | Discussion |
| 2:45 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
