| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session |
| Discussion Leader: Robert Wilson (Australian National University) |
| 3:45 pm - 4:15 pm | Keynote Speaker: Matthew Truppo (Merck & Co)
"My Career in Biotechnology: I Still Don't Know What I Want to Be When I Grow Up... and That's Just Fine"
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| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 8:30 pm | Enzyme Enhancement and Discovery |
| Discussion Leader: Michael Fink (Vienna University of Technology) |
| 7:30 pm - 7:50 pm | Todd Hyster (California Institute of Technology)
"Unnatural Reactivity from Metalloenzymes - Efforts to Develop New C-N Bond Forming Reactions Using p450's"
|
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Christopher Flynn (University of Minnesota)
"Mapping Uncharted Enzymatic Territory: Discovery of Terpenoid Biosynthetic Pathways in Mushrooms"
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| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:30 pm | Selected Short Talks |
| A Series of 5 Minute Presentations Followed by a Group Discussion |
| Discussion Leader: Michael Fink (Vienna University of Technology) |
| 8:30 pm - 8:35 pm | Michael Collett (Children's Medical Research Inn)
"Fine Tuning of Activity of Dynamin I by Alternate Splicing of the Self-Assembly Domain"
|
| 8:35 pm - 8:40 pm | Clarissa Czekster (Yale University)
"Exploring the Flexibility of the Bacterial Translation System" |
| 8:40 pm - 8:45 pm | Rachel Heath (University of Manchester)
"Development of Enzymes for the Synthesis of (S)-Amines" |
| 8:45 pm - 8:50 pm | Hugo van Beek (University of Groningen)
"Stabilization of Cyclohexanone Monooxygenase by a Computationally Designed Disulfide Bond Spanning Only One Residue" |
| 8:50 pm - 8:55 pm | Jochen Wachtmeister (Forschungszentrum Jülich GmbH)
"Affording High Product Concentrations with Biocatalysis: Synthetic Enzyme Cascades of Whole Cell Catalysts in Micro-Aqueous Solvents" |
| 8:55 pm - 9:00 pm | Michael Hicks (Massachusetts Institute of Technology)
"Gene-Based Bioprospecting for Novel Enzymes" |
| 9:00 pm - 9:05 pm | Nikolin Oberleitner (Vienna University of Technology)
"Enzymatic Redox Sequences in Asymmetric Synthesis - Artificial Enzyme Cascades In Vitro and In Vivo" |
| 9:05 pm - 9:10 pm | Titu Devamani (University of Minesota)
"Catalytic Promiscuity of Hydroxynitrile Lyases, Esterases and Related Ancestral Enzymes" |
| 9:10 pm - 9:30 pm | Group Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Enabling Industrial Application of Biocatalysis |
| Discussion Leader: Martin Weissenborn (University of Stuttgart) |
| 9:00 am - 9:20 am | Stephan Hammer (University of Stuttgart)
"Squalene Hopene Cyclases - Potency as Protonases for Stereoselective Brønsted Acid Catalysis"
|
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Catarina Seita (Technical University of Denmark)
"Early-Stage BioProcess Analysis (ESBA)"
|
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Caroline Paul (Delft University of Technology)
"From Styrene to Enantiopure Phenylethanol Derivatives: A Chemo-Enzymatic Cascade"
|
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Stephen Sarria (Georgia Institute of Technology)
"Microbial Synthesis of Pinene"
|
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentorship Component: Career Panel |
| Discussion Leaders: John Woodley (DTU) and Karin Büttner (Universität Leipzig) |
| Frances Arnold (Caltech), Matthew Truppo (Merck & Co), and Stuart Levy (SGL Consulting / ACS)
"What Works for Me?"
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| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
