Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Current Status of Biocatalysis
Discussion Leader: Santosh Shivakumaraswamy (Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, India)
3:45 pm - 4:25 pm
Sabine Flitsch (University of Manchester, United Kingdom)
"Design and Implementation of De Novo Biosynthetic Cascades"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Enzyme Discovery and Characterization
Discussion Leader: Fabio Parmeggiani (University of Manchester, United Kingdom)
7:30 pm - 7:50 pm
Sakonwan Kuhaudomlarp (John Innes Centre, United Kingdom)
"Identification of a Laminaridextrin Phosphorylase from Euglena gracilis and Establishment of a New Glycosyl Hydrolase Family"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Jacek Kozuch (Stanford University, USA)
"The Evolution of Electrostatics in Antibacterial Resistance: Correlating the Active Site Electric Fields Along Evolutionary Trajectories in TEM β-Lactamases"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Anders Knight (California Institute of Technology, USA)
"Diverse Engineered Heme Proteins Enable Stereodivergent Cyclopropanation of Unactivated Alkenes"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Ivana Drienovska (Graz University of Technology, Austria)
"A Designer Enzyme Featuring an Unnatural Amino Acid as a Catalytic Residue"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Enzyme Design and Biocatalysis in Industrial Applications
Discussion Leader: Thilak Reddy Enugala (Uppsala University, Sweden)
9:00 am - 9:20 am
Hai Hoang (Tokyo Institute of Technology, Japan)
"Utilize Pressurized Carbon Dioxide as Novel and Sustainable Reaction Platforms for Biocatalysis"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Fabio Tonin (TU Delft, The Netherlands)
"Redox-Neutral Enzymatic Cascade for the Synthesis of Ursodeoxycholic Acid (UDCA)"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Matthew McDonald (Georgia Institute of Technology, USA)
"In Situ β-Lactam Antibiotic Crystallization to Improve Penicillin G Acylase Performance"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Mafalda Dias Gomes (Technical University of Denmark, Denmark)
"Stability of Enzymes Under Industrial Process Conditions"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Perspectives in Industry and Academia in the Biocatalysis Field
Discussion Leaders: Charlotte Kürten (Science for Life Laboratory / KTH Royal Institute of Technology, Sweden) and Lisa Marx (KTH Royal Institute of Technology, Sweden)
1:30 pm - 2:30 pm
Panel Discussion
Career Perspectives in Industry and Academia in the Biocatalysis Field
David Berkowitz (University of Nebraska, USA)
Jürgen Eck (BRAIN AG, Germany)
Francesco Falcioni (AstraZeneca, United Kingdom)
Nancy Gray (Gordon Research Conferences, USA)
Stefan Lutz (Emory University, USA)
Sabine Flitsch (University of Manchester, United Kingdom)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes