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Biocatalysis (GRS)

Gordon Research Seminar

Unraveling Nature’s Biosynthetic Pathways and Engineering New Reactivity

July 6 - 7, 2024

Chairs

and

Southern New Hampshire University

2500 North River Road

Manchester, New Hampshire, United States

Venue and Travel Information

Conference Description

The Biocatalysis GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

This meeting will focus on interesting biosynthetic pathways, whether natural or engineered, and the methods developed to characterize, discover, and optimize them. This GRS will have a mix of attendees from scientific, engineering, and computational backgrounds.

Related Meeting

This GRS will be held in conjunction with the "Biocatalysis" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm	Keynote Session: New Reactivity from Nature Discussion Leader:
3:45 pm - 3:50 pm	Introduction by Discussion Leader
3:50 pm - 4:20 pm	"Heme Oxygenase-Like Enzymes in Antibiotic Biosynthesis"
4:20 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Discovery, Design, and Construction of Biocatalytic Pathways Discussion Leader:
7:30 pm - 7:45 pm	"A Chemoenzymatic Cascade to Access Chiral Beta-Hydroxy Ketone"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	"Biocompatible Alkene Metathesis in the Yeast Cell Interior"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Establishing a Chemoenzymatic Platform for the Synthesis of Nucleoside Analogues"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Cryptic Sulfotransferases for Aziridine Formation"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"Exploring the Enzymatic Depolymerization of Nylons"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Discovery, Characterization and Engineering of Latent Cannabinoid Cyclase Activity in Marine Bacterial Flavoenzymes"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	New Enzymes and Activities Discussion Leader:
9:00 am - 9:15 am	"New-to-Nature CO₂ Assimilation Pathway Enabled by an Engineered B₁₂ Dependent Mutase"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"Expanding the Enzymatic Toolbox with de Novo Protein Design"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"Biocatalytic Transformations via Abiological Metal Hydrides"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Enantioselective Hydroalkylation of Alkenes using Photoenzymatic Catalysis"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"Enzymatic Enantioselective Nucleophilic Aromatic Substitution"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	"De Novo Design of Serine Hydrolases"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Biocatalysis Beyond Graduate School: Career Perspectives in Industry and Academia Discussion Leader:
1:30 pm - 2:30 pm	Panel Discussion Biocatalysis Beyond Graduate School
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

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Conference History Biocatalysis

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