Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Regulation of Morphogenesis
Discussion Leader: Nils Kröger (TU Dresden, Germany)
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:00 pm
Introduction by Discussion Leader
8:00 pm - 8:25 pm
Jaroslaw Tyszka (Polish Academy of Sciences, Institute of Geological Sciences, Poland)
"Active Morphogenetic Control of Biomineralization in Foraminifera"
8:25 pm - 8:45 pm
Discussion
8:45 pm - 9:10 pm
Assaf Gal (Weizmann Institute of Science, Israel)
"Shaping Mineral Morphologies by Unicellular Algae"
9:10 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cellular and Genetic Control of Mineral Deposition
Discussion Leader: Tali Mass (University of Haifa, Israel)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:40 am
Sylvie Tambutte (Centre Scientifique de Monaco, Monaco)
"Advances in Molecular, Cellular and Physiological Aspects of Coral Calcification"
9:40 am - 10:00 am
Discussion
10:00 am - 10:10 am
Dvir Gur (Weizmann Institute of Science, Israel)
"From Colors to Kidney Stones: The Physicochemical and Biological Control of Organic-Crystal forming Cells"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
Rivka Elbaum (Hebrew University of Jerusalem, Israel)
"Mechanisms of Silica Deposition in Sorghum"
11:10 am - 11:30 am
Discussion
11:30 am - 11:55 am
Monzur Murshed (McGill University, Canada)
"Structure-Function Relationships in Matrix Gla Protein, a Potent Inhibitor of Extracellular Matrix Mineralization"
11:55 am - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Diede de Haan (Weizmann Institute of Science, Israel)
"Exocytosis of the Silicified Cell Wall of Diatoms involves Extensive Membrane Disintegration"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Netta Vidavsky (Ben-Gurion University of the Negev, Israel) and Alex Gagnon (University of Washington, United States)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Ion Transport, Signaling and Homeostasis
Discussion Leader: Marc McKee (McGill University, Canada)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:40 pm
Rodrigo Lacruz (New York University, United States)
"Calcium in Enamel: Not Just Your Regular Mineralizing Cation"
6:40 pm - 7:00 pm
Discussion
7:00 pm - 7:25 pm
Alejandro Rodriguez-Navarro (University of Granada, Spain)
"Avian Eggshell Structure and Mineralization"
7:25 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Claudia Goettsch (RWTH Aachen University, Germany)
"The Role of the Endomembrane Homeostasis in Ectopic Calcification"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Chemical and Computational Models of Nucleation, Phase Transformation and Growth
Discussion Leader: Wendy Shaw (Pacific Northwest National Laboratory, United States)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:40 am
Jim Pfaendtner (University of Washington, United States)
"Energetics and Mechanism of Silica Biomineralization Mediated by Peptoids"
9:40 am - 10:00 am
Discussion
10:00 am - 10:10 am
Maria Feofilova (ETH Zurich, Switzerland)
"Frustrated Frustules: Geometric Frustration in Diatom Frustules"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
Fiona Meldrum (University of Leeds, United Kingdom)
"In Vitro Approaches to Understanding Calcite/ Aragonite Polymorphism in Biomineralization"
11:10 am - 11:30 am
Discussion
11:30 am - 11:55 am
Thomas Koop (Bielefeld University, Germany)
"Biomolecular Control of the Nucleation and Growth of Ice Crystals"
11:55 am - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Liza-Anastasia DiCecco (McMaster University, Canada)
"Visualizing Calcium Phosphate Mineralization Dynamics through Novel in situ Liquid TEM"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Macromolecules in Biomineralization
Discussion Leader: Elia Beniash (University of Pittsburgh, United States)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:40 pm
Michiko Nemoto (Okayama University, Japan)
"Identification of Proteins Involved in Chiton Tooth Biomineralization by RNA-Seq-Based Analyses"
6:40 pm - 7:00 pm
Discussion
7:00 pm - 7:25 pm
André Scheffel (Technische Universität Dresden, Germany)
"The Molecular Mechanism of Calcite Biomineralization in Coccolithophores"
7:25 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Rachael Deis (Weizmann Institute, Israel)
"Unraveling the Molecular Mechanisms underlying Intracellular Crystal Formation"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Structure and Biomechanics
Discussion Leader: Peter Fratzl (Max Planck Institute of Colloids and Interfaces, Germany)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:40 am
Derk Joester (Northwestern University, United States)
"From Nano- to Mesoscale: The Structure of Dental Enamel"
9:40 am - 10:00 am
Discussion
10:00 am - 10:10 am
Neha Mehta (CNRS, France)
"Spectroscopy Insights into Intracellular Amorphous Calcium Carbonate (ACC) formed by Cyanobacteria"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
Elena Sturm (Ludwig Maximilian University of Munich, Germany)
"What Can We Still Learn from Tooth of Darwin’s Dreampond?"
11:10 am - 11:30 am
Discussion
11:30 am - 11:55 am
Tamara Alliston (UCSF, United States)
"Osteocyte Control of Bone Structure and Function in Skeletal Aging"
11:55 am - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Liuni Chen (Virginia Tech, United States)
"Biomineralized Light-Guiding Structures in Starfish Protoreaster Nodosus"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Biomineralization Principles Translated
Discussion Leader: Sherif Elsharkawy (King's College London, United Kingdom)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:40 pm
Luiz Bertassoni (Oregon Health and Science University, United States)
"Biomimetic Mineralization in Cell-laden Hydrogels for Tissue Regeneration and Understanding Cancer Metastasis"
6:40 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
Jonas Schwan (University of Bayreuth, Germany)
"Bioinspired Preparation of Organic-Inorganic Hybrid Microscrolls by Strain-Induced Self-Rolling of Electrochemically Deposited Cobalt Hydroxide Films"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Camila Tovani (Sorbonne Université, France)
"Self-Assembled Biomimetic Collagen/Apatite Scaffold from Hybrid Microparticles to Reconstruct Hard Tissues"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Dimitra Athanasiadou (University of Toronto, Canada)
"DNA Hydrogels as Scaffolds for Calvarial Bone Regeneration"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Elena Macias-Sanchez (University of Granada, Spain)
"Spherulitic Crystal Growth drives Mineral Deposition Patterns in Collagen-Based Materials"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Biominerals in Pathology
Discussion Leader: Willi Jahnen-Dechent (RWTH Aachen University, Germany)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:40 am
Peter Vekilov (University of Houston, United States)
"Cooperativity and Reversibility in the Regulation of Hematin Crystallization by Antimalarials"
9:40 am - 10:00 am
Discussion
10:00 am - 10:10 am
Amit Cohen (Ben-Gurion University of the Negev, Israel)
"The Relationship between Crystal Properties of Microcalcifications and Breast Precancer Progression in a 3D in vitro Model"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
Sunita Ho (University of California San Francisco, United States)
"Zinc and Phosphorus: Foretellers of Pathologic Mineralization"
11:10 am - 11:30 am
Discussion
11:30 am - 11:55 am
Sun Peck (Vanderbilt University Medical Center, United States)
"Extracellular Matrix Microenvironment in Heterotopic Ossification"
11:55 am - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Olivier Duverger (NIDCR/NIH, United States)
"Missteps in the Complex Choreography of Ameloblasts: Mechanism leading to Enamel Ultrastructure Disruption in Disease"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Keynote Session: Geochemistry, Proxies and Evolution
Discussion Leader: Derk Joester (Northwestern University, United States)
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:30 pm
Alex Gagnon (University of Washington, United States)
"The Geochemistry of Biomineralization: The Effects of Nucleation, Organic-Mineral Interactions, and Ion Transport on Paleoclimate Proxies"
6:30 pm - 6:50 pm
Discussion
6:50 pm - 7:15 pm
Andrew Knoll (Harvard University, United States)
"Silica Biomineralization: Evolutionary and Biogeochemical Consequences"
7:15 pm - 7:35 pm
Discussion
7:35 pm - 7:50 pm
General Discussion
7:50 pm - 8:00 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure