Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: An Expanding Genetic Code
Discussion Leaders: Kristen DeMeester (University of Delaware, USA) and Tyler Bechtel (Boston College, USA)
3:45 pm - 4:15 pm
Peter Schultz (The Scripps Research Institute, USA)
"An Expanding Genetic Code"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Proteomics and Permutations: Molecular Activity in Biology
Discussion Leaders: Kalie Mix (University of Wisconsin-Madison, USA) and Rumit Maini (The University of Tokyo, Japan)
7:30 pm - 7:50 pm
Christine Kaiser (AstraZeneca, USA)
"Small-Molecule Modulation of Antibody Structure and Function"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Christopher Parker (The Scripps Research Institute, USA)
"Expanding the Ligandable Proteome: Ligand and Target Discovery by Fragment-Based Screening in Cells"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Rhushikesh Kulkarni (National Cancer Institute, NIH, USA)
"Chemoproteomic Portrait of the Oncometabolite Fumarate"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Rumit Maini (The University of Tokyo, Japan)
"Ribosomal Synthesis of Thioamide Bond via Genetic Code Reprogramming"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Recognition and Reporting: Reading Biology Through the Lens of Chemistry
Discussion Leaders: Mia Huang (University of California, San Diego, USA) and Siddharth Matikonda (University of Otago, New Zealand)
9:00 am - 9:20 am
Antoinette Blom (California Institute of Technology, USA)
"Probing Drug Binding Interactions in Receptors of the Central Nervous System"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Joshua Yim (Stanford University School of Medicine, USA)
"Developing Optical Chemical Probes for Imaging Proteolytic Signatures"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Brittany Morgan (Duke University, USA)
"Design, Synthesis and Evaluation of Small Molecule Libraries for the Selective Recognition of Therapeutically Relevant RNA"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Neena Pyzocha (Broad Institute of MIT and Harvard, USA)
"Discovery and Biochemical Characterization of Cas13b, a CRISPR-Associated RNase"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader: Zachary Hill (University of California, San Francisco, USA)
1:30 pm - 2:30 pm
Panel Discussion
Leaving the Bench: Non-Traditional Careers for Bioorganic Chemists
Adel Elsohly (University of California, Berkeley, USA)
Bethany Halford (Chemical and Engineering News, USA)
Erik Spek (Vedanta Biosciences, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
