Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Chemical Tricks for Drugging the Undruggable
3:45 pm - 4:20 pm
"Chemical Tricks for Drugging the Undruggable"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Developing Biochemical Methods to Combat Disease
7:30 pm - 7:45 pm
"Quantitative Chemical Proteomics to Evaluate Lipid Kinase Inhibitor Binding Profiles"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"Mapping Proteolysis at the Surface of Living Cells"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"Designing Peptide Analogs to Control Streptococcus pneumoniae Infectivity Through Quorum Sensing Modulation"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"Enterococcus faecium Secreted Antigen A Remodels Peptidoglycan Fragments to Trigger Host Immunity"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Discovery of a Gut Bacterial Phospholipase D that Supports Disease-Associated Choline Metabolism"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Designing Chemical Probes to Illuminate Biology
9:00 am - 9:15 am
"Protected Triazabutadienes for Aryl Diazonium Generation"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Metallophotoredox-Catalyzed Protein Functionalization Enables the Synthesis of Pure Epigenetic Species for Defined Biophysical Interaction Studies"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Peptide Based Therapeutics for Global Non-Communicable Diseases"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Biochemical Characterization of Oxygenases in Saxitoxin Biosynthesis"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
"From Synthesis to Pathology: Identifying Glucosepane's Role in Diabetes and Aging"
10:35 am - 10:40 am
Discussion
10:40 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Careers in Industry, Academia and Beyond: The Insiders' Perspective
1:30 pm - 1:55 pm
"Through the Lens of a Bioorganic Industrial Chemist: The Discovery of Small Molecules Utilized to Cure Chronic Hepatitis C Virus Infection: Ledipasvir, Velpatasvir and Voxilaprevir"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:30 pm
Panel Discussion
Careers in Industry, Academia and Beyond: The Insiders' Perspective
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes