Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Chemical Biology as a Tool for Elucidating the Biological Roles of Carbohydrates
A dynamic research talk by Prof. Laura Kiessling of MIT.
Discussion Leaders: Pratik Kumar (Stony Brook University, USA) and Natalia Milosevich (University of Victoria, Canada)
3:45 pm - 4:15 pm
Laura Kiessling (Massachusetts Institute of Technology, USA)
"Chemical Biology as a Tool for Elucidating the Biological Roles of Carbohydrates"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Applying Chemistry to Understand Biological Processes
Discussion Leaders: David Cardoso (University of Sydney, Australia) and Ziyang Zhang (University of California, San Francisco, USA)
7:30 pm - 7:50 pm
Esther Kemper (Scripps Research, USA)
"Global Discovery of Phosphorylation-Dependent Cysteine Ligandability in Cancer Cells"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Kayvon Pedram (Stanford University, USA)
"Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx Reveals a Nanoscale Organization that Is Actively Remodeled During Cancer Progression"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Jasmine Bickel (Imperial College London, United Kingdom)
"Design and Development of Novel Peptide-Based Inhibitors of hCD59"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Roger Ashmus (Simon Fraser University, Canada)
"Development of Novel Fluorescence-Quenched Probes for Monitoring Lysosomal Glycosidase Activity in Live Cells"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Engineering Chemical Tools to Modulate Biology / Mentorship Component: Careers Beyond Academia and Industry
Discussion Leaders: Stephanie Breunig (California Institute of Technology, USA) and Simone Rauch (The University of Chicago, USA)
9:00 am - 9:20 am
Huiqing Zhou (University of Chicago, USA)
"Evolution of a Reverse Transcriptase to Map N1-Methyladenosine in Human mRNA"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Daniel Schwarz (University of California, San Francisco, USA)
"Pharmacological Inhibition of Pin1 Lacks Defining Features of Pin1 Knockdown"
9:50 am - 10:00 am
Discussion
10:00 am - 11:00 am
Panel Discussion
Careers Beyond Academia and Industry
Luke Lavis (Janelia Research Campus, Howard Hughes Medical Institute, USA)
Parag Mahanti (Novartis, USA)
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Translation of Chemical Tools: Off the Bench and into the World
Discussion Leaders: Pei Liu (University of California, Berkeley, USA) and Lucas Ryan (Southern Methodist University, USA)
1:30 pm - 1:50 pm
Christian Fischer (New York University, USA)
"Water-Soluble, Organic Fluorophores with Powerful Electrochemical and Photophysical Properties"
1:50 pm - 2:00 pm
Discussion
2:00 pm - 2:20 pm
Matthew Volpe (Harvard University, USA)
"In Vitro Characterization of the Colibactin-Activating Peptidase ClbP Enables Development of a Fluorogenic Activity Probe"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes