Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Chemical Biology as a Tool for Elucidating the Biological Roles of Carbohydrates
A dynamic research talk by Prof. Laura Kiessling of MIT.
3:45 pm - 4:15 pm
"Chemical Biology as a Tool for Elucidating the Biological Roles of Carbohydrates"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Applying Chemistry to Understand Biological Processes
7:30 pm - 7:50 pm
"Global Discovery of Phosphorylation-Dependent Cysteine Ligandability in Cancer Cells"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx Reveals a Nanoscale Organization that Is Actively Remodeled During Cancer Progression"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Design and Development of Novel Peptide-Based Inhibitors of hCD59"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Development of Novel Fluorescence-Quenched Probes for Monitoring Lysosomal Glycosidase Activity in Live Cells"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Engineering Chemical Tools to Modulate Biology / Mentorship Component: Careers Beyond Academia and Industry
9:00 am - 9:20 am
"Evolution of a Reverse Transcriptase to Map N1-Methyladenosine in Human mRNA"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Pharmacological Inhibition of Pin1 Lacks Defining Features of Pin1 Knockdown"
9:50 am - 10:00 am
Discussion
10:00 am - 11:00 am
Panel Discussion
Careers Beyond Academia and Industry
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Translation of Chemical Tools: Off the Bench and into the World
1:30 pm - 1:50 pm
"Water-Soluble, Organic Fluorophores with Powerful Electrochemical and Photophysical Properties"
1:50 pm - 2:00 pm
Discussion
2:00 pm - 2:20 pm
"In Vitro Characterization of the Colibactin-Activating Peptidase ClbP Enables Development of a Fluorogenic Activity Probe"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes