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Bioorganic Chemistry (GRS)

Gordon Research Seminar

Chemical Biology to Address Biological Intricacy

June 10 - 11, 2023
Chairs and
Proctor Academy
204 Main Street
Andover, New Hampshire, United States
 Venue and Travel Information

Conference Description

The Bioorganic Chemistry GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

The Bioorganic Chemistry Gordon Research Seminar (GRS) precedes the related GRC, allowing graduate students, post-doctoral researchers and other early career scientists the unique opportunity to network and discuss emerging science with peers. The GRS allows meaningful interactions with keynote speakers and will offer additional professional development sessions to expose attendees to a variety of career opportunities in chemical biology.

The 2023 Bioorganic Gordon Research Seminar will focus on ever-evolving chemical tools and strategies for addressing diverse biological challenges. To highlight emerging scholarship, attendees are encouraged to present their unpublished data.

Related Meeting

This GRS will be held in conjunction with the "Bioorganic Chemistry" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Translational Chemoproteomics
Discussion Leader:
3:45 pm - 4:20 pm
"Activity-Based Proteomics – Protein and Ligand Discovery on a Global Scale"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Chemical Tools to Interrogate Biology
Discussion Leader:
7:30 pm - 7:45 pm
"Post-Translational Chemical Manipulation of Non-Natural Ribosomal Products via Acyl Rearrangement"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"Targeting Myc Activity Using Modular bHLH-Derived Synthetic Transcriptional Repressors"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"Conformationally Responsive Dyes Enable Protein-Adaptive Differential Scanning Fluorimetry"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"A Class of Secreted Mammalian Peptides with Potential to Expand Cell-Cell Communication"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Exploiting Thioether Reactivity for Labeling Mycobacterial Glycans"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Transfer Tuning: Turn-on Voltage-Sensitive Indicators for Hyperpolarized Membranes"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Omics Approaches
Discussion Leader:
9:00 am - 9:15 am
"Measuring Humoral Immune Response to Cancer Development and Treatment via Plasma Amino Acid Signatures by Utilizing Bioorthogonal Chemistry and Machine Learning"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Chemically Triggered Bioorthogonal Probes to Tag RNA Structures"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Evaluation of the Differential Binding Preferences of Histone Trimethyllysine Reader Proteins"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"CRISPR-Mediated Intracellular Selection of RNA Aptamers"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Template-Assisted Covalent Modification of DCAF16 Underlies Activity of BRD4 Molecular Glue Degraders"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
"Rational Chemical Design of Molecular Glue Degraders"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Careers at the Interface of Chemistry and Biology
Discussion Leaders: and
1:30 pm - 2:05 pm
"Adventures in Drug Hunting"
2:05 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes

Contributors

Expansion Therapeutics, Inc.
Scorpion Therapeutics

Conference Links

Conference History Bioorganic Chemistry
Additional Fee Info

Bioorganic Chemistry
June 15 - 20, 2025


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