SUNDAY |
2:00 pm - 11:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | OPENING KEYNOTE LECTURE |
8:00 pm - 9:00 pm | Raphael Mechoulam (Department of Medicinal Chemistry and Natural Products, The Hebrew University, Jerusalem, Israel) "Cannabidiol: pharmacological effects of a major cannabis constituent" |
9:00 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ENDOCANNABINOID SIGNALING IN THE CNS |
| Discussion Leader: Ken Mackie (Dept. of Psychological & Brain Sciences, Indiana University, USA) |
9:00 am - 9:15 am | Ken Mackie (Dept. of Psychological & Brain Sciences, Indiana University, USA) "Introduction" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:50 am | Vincenzo Di Marzo (Endocannabinoid Research Group, Napoly, Italy) "Endocannabinoid signalling in CNS: control of energy intake and metabolism" |
9:50 am - 10:00 am | Discussion |
10:00 am | Group Photo / Coffee Break |
10:30 am - 10:55 am | Benjamin F. Cravat III (Depts. of Cell Biology and Chemistry, The Scripps Research Institute, USA) "The enzymatic regulation of endocannabinoid signaling" |
10:55 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Brad Alger (University Of Maryland, Baltimore, USA) "Regulation of endocannabinoid signaling in the hippocampus" |
11:35 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | David Lovinger (Laboratory For Integrative Neuroscience, N.I.A.A.A. Rockville, USA) "Regulated endocannabinoid release contributes to retrograde signaling" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | ENDOCANNABINOIDS AND NEURONAL CIRCUITRY: PAIN |
| Discussion Leader: Andrea Hohmann (University of Georgia, USA) |
5:30 pm - 5:45 pm | Andrea Hohmann (University of Georgia, USA) "Cannabinoids as pharmacotherapies for neuropathic pain" |
5:45 pm - 5:50 pm | Discussion |
5:50 pm - 6:10 pm | Philip T. Malan Jr (Anesthesiology & Pharmacology, University of Arizona, USA) "CB2 cannabinoid receptors and pain" |
6:10 pm - 6:20 pm | Discussion |
6:20 pm - 6:40 pm | MacDonald J. Christie (Pain Management & Research Center, University of Sydney, Australia) "Cellular and synaptic mechanisms of cannabinoids in pain pathways" |
6:40 pm - 6:50 pm | Discussion |
6:50 pm - 7:10 pm | Irmgard Tegeder (Institute for Clinical Pharmacology, Frankfurt am Main, Germany) "Peripheral endogenous pain control through CB1 receptors - lessons from CB1-SNScre mice"
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7:10 pm - 7:20 pm | Discussion |
7:20 pm - 7:30 pm | Joelle Chabry (Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France) - selected from abstracts "Nonpsychoactive cannabidiol prevents prion accumulation and protects neurons against prion toxicity" |
8:00 pm | Dinner |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ENDOCANNABINOIDS AND NEURONAL CIRCUITRY: REWARD |
| Discussion Leader: Rafael Maldonado (Dept Neuropharmacology, Pompeu Fabra University, Barcelona, Spain) |
9:00 am - 9:15 am | Rafael Maldonado (Dept Neuropharmacology, Pompeu Fabra University, Barcelona, Spain) "Involvement of the endocannabinoid system in drug addiction and pain control" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:40 am | Taco J. De Vries (Anatomy & Neuroscience, Amsterdam, Netherland) "CB1 receptors control the impact of drug- and food-associated stimuli" |
9:40 am - 9:50 am | Discussion |
9:50 am - 10:10 am | Emmanuel Valjent (INSERM, Paris, France) "Role of CB1 receptors in locomotor activity and striatal signaling in response to psychostimulants" |
10:10 am - 10:20 am | Discussion |
10:20 am | Coffee Break |
10:50 am - 11:10 am | Steven R. Goldberg (N.I.D.A, Baltimore, USA) "Endocannabinoid system activity and the motivational control of drug-reinforced behavior" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:40 am | Loren Parson (Scripps Research Institute, La Jolla, USA) "Drug-induced alterations in extracellular endocannabinoid levels in vivo: involvement in drug reinforcement, dependence and relapse" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:10 pm | Carl Lupica (N.I.D.A, Baltimore, USA) "Interactions between marijuana and the endocannabinoid system: What can we THC?" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Joe Cheer (Albany Medical College, Albany, USA) - selected from abstracts "Cannabinoid receptors control encoding of motivated behavior in real-time" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | ENDOCANNABINOIDS AND NEURONAL CIRCUITRY: LEARNING AND PLASTICITY |
| Discussion Leader: Pablo E. Castillo (Albert Einstein Coll Med, Bronx, NY, USA) |
5:30 pm - 5:45 pm | Pablo E. Castillo (Albert Einstein Coll Med, Bronx, NY, USA) "Molecular mechanisms underlying endocannabinoid-mediated LTD" |
5:45 pm - 5:50 pm | Discussion |
5:50 pm - 6:10 pm | David M Robbe (Molecular & Behavioral Neuroscience, Rutgers University, USA) "Antagonistic effects of cannabinoids on hippocampal and thalamo-cortical oscillations" |
6:10 pm - 6:20 pm | Discussion |
6:20 pm - 6:40 pm | Carsten Wotjak (Max-Planck Institute of Psychiatry, Munich, Germany) "As fear goes by: role of CB1 in fear and anxiety" |
6:40 pm - 6:50 pm | Discussion |
6:50 pm - 7:10 pm | Anatol Kreitzer (Gladstone Institute of Neurological Disease University of California, San Francisco, USA) "Striatal synaptic plasticity and the control of movement" |
7:10 pm - 7:20 pm | Discussion |
7:20 pm - 7:30 pm | Tommy Pattij (Center for Neurogenomics and Cognitive Research, Amsterdam, Netherlands) - selected from abstracts "Cannabinoid involvement in distinct forms of impulsive behavior in rats" |
8:00 pm | Dinner |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ENDOCANNABINOIDS: NEUROINFLAMMATION AND SIGNALING IN GLIAL CELLS |
| Discussion Leader: Nephi Stella (University of Washington, Seattle, USA) |
9:00 am - 9:15 am | Nephi Stella (University of Washington, Seattle, USA) "Cannabinoid function in microglia" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:40 am | David Baker (University College, London, UK) "Control of multiple sclerosis by avoiding the pyschoactivity associated with medical cannabis" |
9:40 am - 9:50 am | Discussion |
9:50 am - 10:10 am | Oliver Ullrich (University of Zurich, Faculty of Medicine, Institute of Anatomy) "Immune surveillance of the central nervous system: the role of endocannabinoids" |
10:10 am - 10:20 am | Discussion |
10:20 am | Coffee Break |
10:50 am - 11:10 am | Carmen Guaza (Instituto de Neurobiología Cajal, Madrid, Spain) "Cannabinoids and neuroinflammation: from immunomodulation to neuroprotection" |
11:10 am - 11:20 am | Discussion |
11:20 am - 12:30 pm | Carl Lupica’s Data Blitz (N.I.D.A, Baltimore, USA) "2 slides, 5 min presentation, 2 min discussion, selected from posters & abstracts" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:00 pm | ENDOCANNABINOIDS AND NEURAL DEVELOPMENT |
| Discussion Leader: David A. Greenberg (Buck Institute for Age Research, Novato, USA) |
5:30 pm - 5:40 pm | David A. Greenberg (Buck Institute for Age Research, Novato) "Introduction" |
5:40 pm - 6:00 pm | Tibor Harkany (Karolinska, Stockholm, Sweden) "Endocannabinoids: morphogens controlling CNS patterning" |
6:00 pm - 6:10 pm | Discussion |
6:10 pm - 6:20 pm | Ismael Galve-Roperh (Universidad Complutense, Madrid, Spain) "The endocannabinoid system and neurogenesis in excitotoxicity" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Pat Doherty (The Wolfson CARD, London, UK) "The regulated expression of DAG lipases allows for multiple functions for endocannabinoid signalling during development and in the adult" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
8:00 pm | Dinner |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | NEW TOOLS IN CANNABINOID RESEARCH |
| Discussion Leader: Beat Lutz (Institute of Physiological Chemistry and Pathobiochemistry, Mainz, Germany) |
9:00 am - 9:15 am | Beat Lutz (Institute of Physiological Chemistry and Pathobiochemistry, Mainz, Germany) "Tricks and tracks of mouse genetics" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:40 am | Mauro Maccarrone (Department of Biomedical Sciences, Teramo, Italy) "Visualization of transmembrane transport and intracellular storage of anandamide by means of a novel biotinylated tool" |
9:40 am - 9:50 am | Discussion |
9:50 am - 10:10 am | Joseph P.Y. Kao (University of Maryland, Baltimore, USA) "Controlling endocannabinoid signaling with light" |
10:10 am - 10:20 am | Discussion |
10:20 am | Coffee Break |
10:50 am - 11:10 am | Lakshmi Devi (Mount Sinai, New York, USA) "Conformation-sensitive antibodies to cannabinoid receptors" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:40 am | Michael Kavanaugh (University Of Montana, USA) "Fluorescence-based measurement of endocannabinoid transport kinetics and distribution in brain" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:10 pm | Peter Greasley (AstraZeneca R&D, Mölndal, Sweden) "The search for novel targets of cannabinoid ligands" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Linus Lin (Merck Research Laboratories, Rahway NJ, USA) - selected from abstracts "[18F]MK-9470, first CB1 PET tracer suitable for clinical use" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:00 pm | ENDOCANNABINOIDS IN CENTRAL AND PERIPHERAL METABOLIC REGULATION |
| Discussion Leader: George Kunos (N.I.A.A.A., Bethesda, USA) |
5:30 pm - 5:45 pm | George Kunos (N.I.A.A.A., Bethesda, USA) "Introduction" |
5:45 pm - 5:50 pm | Discussion |
5:50 pm - 6:10 pm | George Kunos (N.I.A.A.A., Bethesda, USA) "Endocannabinoids and energy homeostasis: central and peripheral mechanisms" |
6:10 pm - 6:20 pm | Discussion |
6:20 pm - 6:40 pm | Uberto Pagotto (S. Orsola-Malpighi Hospital, Bologna, Italy) "How CB1 KO mice may help to understand the role of endocannabinoids in the regulation of metabolism and food intake" |
6:40 pm - 6:50 pm | Discussion |
6:50 pm - 7:30 pm | CLOSING KEYNOTE LECTURE |
6:50 pm - 7:20 pm | Daniele Piomelli (Dept Pharmacology, University California, Irvine, USA) "The endocannabinoid system: a drug discovery perspective" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |