Sunday, June 22, 1997
- Registration begins at 2 p.m.
- Dinner will be at 6 p.m.
- 7:30 - 8:00 p.m. - Introductory remarks; Welcome
SYNTHESIS
Discussion Leader: Dr. Robert Giuliano
- 8:00 - 8:30 p.m. - Novel Carbohydrate Derivatives as Probes of Carbohydrate - Protein Interactions
(Dr. 0. Hindsgaul)
- 8:30 - 8:45 - Discussion
- 8:45 - 9:15 - A Latent-Active Glycosylation Strategy for the Preparation of Oligosaccharide Libraries
(Dr. G.-J.Boons)
- 9:15 - 9:30 - Discussion
- 9:30 - Social hour
Monday, June 23, 1997
SYNTHESIS
Discussion Leader: Dr. Robert Giuliano
- 9:00 - 9:30 a.m. - Construction of Carbohydrates on the Nanoscale
(Dr. F. Stoddart)
- 9:30 - 9:45 - Discussion
- 9:45 - 10:15 - Aspects of the Inhibition of Glycan Hydrolases and Synthases
(Dr. R. Stick)
- 10:15 - 10:30 - Discussion
- 10:30 - 11:30 - Coffee break/Photo session
Discussion Leader: Dr. Vince Pozsgay
- 11:30 - 12:00 - Exploring Multivalent Protein-Saccharide Interactions with Synthetic Ligands
(Dr. L. Kiessling)
- 12:00 - 12:15 - Discussion
- 12:30 - Lunch
- 5:00 - 6:00 p.m. - Poster session
- 6:00 - Dinner
SYNTHESIS
Discussion Leader: Dr. Vince Pozsgay
- 7:30 - 8:00 p.m. - Carbohydrates, Samarium Diiodide and Mycobacteria
(Dr. J.-M. Beau)
- 8:00 - 8:15 p.m. - Discussion
- 8:15 - 8:45 p.m. - Cell Adhesion Carbohydrate Ligands: Synthesis and Biological Significance
(Dr. M. Kiso)
- 8:45 - 9:00 p.m. - Discussion
- 9:00 - 9:30 p.m. - 1,3- Dioxolenium Ion-Alkene Cyclizations: A Novel Approach to C-glycosides
(Dr. D. Mootoo)
- 9:30 - 9:45 p.m. - Discussion
- 9:45 p.m. - Social hour / Poster session
Tuesday, June 24, 1997
GLYCOBIOLOGY
Discussion Leader: Dr. Subramaniam Sabesan
- 9:00 - 9:30 a.m. - Computer-Assisted Design of Selectin Antagonists
(Dr. B. Ernst)
- 9:30 - 9:45 a.m. - Discussion
- 9:45 - 10:15 a.m. - The 0-acetyl and N-acetyl Groups of Sialic Acids - Their Comings and Goings
(Dr. R. Chammas)
- 10:15 - 10:30 a.m. - Discussion
- 10:30 - I 1:00 a.m. - Coffee Break
- 11:00 - 11:30 a.m. - Effects of Size, Shapes and Valency in Multiple Carbohydrate-Protein Interactions
(Dr. R. Roy)
- 11:30 - 11:45 a.m. - Discussion
- 11:45 - 12:15 a.m. - Biological Significance of Glycosylation of Immunoglobulins
(Shantha Raju)
- 12:15 - 12:30 p.m. - Discussion
- 12:30 p.m. - Lunch
- 5:00 - 6:00 p.m. - Poster session
- 6:00 p.m. - Dinner
GLYCOBIOLOGY
Discussion Leader: Dr. Subramaniam Sabesan
- 7:30 - 8:00 p.m. - The Therapeutic Ability of Anti-Adhesive Oligosaccharides in Infectious Diseases
(Paul Simon)
- 8:00 - 8:15 p.m. - Discussion
- 8:15 - 8:45 p.m. - The Physical Origin of Carbohydrate-Protein Affinity
(Eric Toone)
- 8:45 - 9:00 p.m. - Discussion
- 9:00 - 9:15 p.m. - Business session: Announcement of candidates for Vice-chair
- 9:15 p.m. - Social hour / Poster session
Wednesday, June 25, 1997
CARBOHYDRATE - PROCESSING AND MODIFYING ENZYMES
Discussion Leader: Dr. Eric Toone
- 8:15 - 8:45 a.m. - Glycosynthases: New Enzymes for Oligosaccharide Synthesis
(Dr. S. Withers)
- 8:45 - 9:00 a.m. - Discussion
- 9:00 - 9:30 a.m. - Structure, Mechanism, and Specificity of the Inverting exo-L-Glucanase, Glucoamylase
(Dr. B. Svensson)
- 9:30 - 9:45 a.m. - Discussion
- 9:45 - 10:15 a.m. - New Mechanistic Aspects of Glycoside Hydrolysis
(Dr. A. Bennet)
- 10: 15 - 10:30 a.m. - Discussion
- 10:30 - 11:00 a.m. - Coffee Break
- 11:00 - 11:30 a.m. - Glycosyl Transferases in Oligosaccharide Synthesis
(Dr. M. Palcic)
- 11:30 - 11:45 a.m. - Discussion
- 11:45 - 12:15 a.m. - Mechanistic Studies on Carbohydrate-Modifying Enzymes
(Dr. M. Tanner)
- 12:15 - 12:30 p.m. - Discussion
- 12:30 p.m. - Lunch
- 5:00 - 6:00 p.m. - Poster Session
- 6:00 p.m. - Dinner
CONFORMATIONAL ANALYSIS
Discussion Leader: Dr. David Bundle
- 7:30-8:00 p.m. - Induced Fit Binding of Carbohydrate Ligands to Receptor Proteins
(Dr. T. Peters)
- 8:00-8:15 p.m. - Discussion
- 8:15-8:45 p.m. - Studies on the Protein-Bound Conformations of Carbohydrates and Analogues by TRNOE Experiments
(Dr. J. Jiniinez-Barbero)
- 8:45 - 9:00 p.m. - Discussion
- 9:00 p.m. - Social hour / Poster session
Thursday, June 26, 1997
CONFORMATIONAL ANALYSIS
Discussion Leader: Dr. David Bundle
- 8:45-9:15 a.m. - X-ray Crystallographic and Molecular Modeling Studies of Protein-Carbohydrate and Carbohydrate-Carbohydrate Interactions
(Dr. A. Imberty)
- 9:15-9:30 a.m. - Discussion
- 9:30- 1 0:00 a.m. - The Effect of Peptide Glycosylation Studied by Fluorescence Energy Transfer
(Dr. J. Duus)
- 10:00- 10: 15 a.m. - Discussion
- 10: 15 - 10:45 a.m. - Coffee Break
Discussion Leader: Dr. Klaus Bock
- 10:45- 11:15 a.m. - Computing Binding Free Energies: Application to Salmonella 0-Antigen - Antibody Interactions
(Dr. R. Woods)
- 11: 15-11:30 a.m. - Discussion
- 11:30 - 12:00 a.m. - Applications of Stable Isotopes in NMR Studies of Carbohydrates
(Dr. A. Serianni)
- 12:00 - 12:15 p.m. - Discussion
- 12:15 - 12:30 p.m. - Business session: Election of Vice-chair by ballot
- 12:30 p.m. - Lunch
- 5:00 - 6:00 p.m. - Poster session
- 6:00 p.m. - Banquet
CONFORMATIONAL ANALYSIS
Discussion Leader: Dr. Klaus Bock
- 8:00 - 8:30 p.m. - Neural Networks
(Dr. B. Meyer)
- 8:30 - 8:45 p.m. - Discussion
- 8:45 - 9:15 p.m. - Screening Mixtures for Biological Activity by NMR
(Dr. T. Peters/Dr. B. Meyer)
- 9:15 -9:30 p.m. - Discussion
- 9:30 - 9:45 p.m. - Business session: Announcement of Vice-chair / Evaluation
- 9:45 p.m. - Closing Remarks
Friday, June 27, 1997
- 7:30 - 8:30 a.m. - Breakfast
- 9:00 a.m. - Buses leave for Logan Airport
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