| June 20th, 1999 | Biological Relevance of Carbopeptides |
Discussion Leader: S.M. Hecht
Sunday, 7:30 p.m.
B.M. Pinto "Exploring the basis of peptide - carbohydrate cross-reactivity"
G. Fleet "Carbopeptides - Sequencamers or Foldamers - Maybe
just diversity? "
| June 21st, 1999 | Oligosaccharide Synthesis |
Discussion Leader: G.-J. Boons
Monday. 8:30 a.m.
R.R. Schmidt "New aspects of glycoside bond formation"
K. Bock "Advantages of new resins for carbohydrate chemistry
on solidphase "
Coffee Break
P.H. Seeberger "Synthesis of oligosaccharides in solution and on solid support
using glycal derived building blocks "
Lunch
Monday, 7:30 p.m.
Y. Chapleur "New receptor ligands using stereochemically diverse libraries
of carbohydrates "
D. Crich "ß-Mannosides: Chemical synthesis"
| June 22nd , 1999 | Carbohydrates Function and Synthesis |
Discussion Leader: G. Descotes
Tuesday, 9:00 a.m.
S.M. Hecht "Carbohydrates as participants in protein synthesis andjunction"
H. Spaink "Synthesis and biological function of chitin oligosaccharides
and derivatives thereof"
Coffee Break
G. Magnusson "Ganglioside - based neoglycoconjugates: synthesis and
biological application "
Lunch
Tuesday, 7:30 p.m.
P.A. Driquez "Carbohydrates with anticoagulant and antithrombotic activities:
a synthetic approach"
M. Martin - Lomas "The chemistry of inositolphosphoglycans and their role in
intracellular signal transduction "
J. Gervay "Can carbohydrates serve as protein mimics"
| June 23rd , 1999 | Sugar Mimetics, Antibiotics and Inhibitors |
Discussion Leader: W. Klaffke
Wednesday, 9:00 a.m.
P. Vogel "Synthesis of sugar mimetics and their glycosidase
inhibitory activities "
D.E. Kane "On the chemistry and biochemistry of glycopeptide antibiotics"
Coffee Break
B. Ganem "Metabolic blockades using sugar mimics"
Lunch
Wednesday, 7:30 p.m.
H. Overkleeft "Use of carbohydrates as scaffolds for ring-closing metathesis"
M. Bols "Intramolecular debenzylation: discovery of a new reaction"
I. Lundt "From sugar lactones to sugar mimics"
| June 24th, 1999 | Molecular Recognition of Oligosaccharides |
Discussion Leader: T.L. Lowary
Thursday, 9:00 a.m.
O. Kanie "Investigation of a supramolecular device that inhibits
a carbohydrate receptor "
Y. Ito "Synthetic challenges in glycoprotein glycans"
Coffee Break
D.R. Bundle "Design, synthesis and crystal structure of soluble sub-nanomolar
inhibitors for shiga like toxins "
Lunch
| June 24th, 1999 | Structural and Conformational Analysis of Complex
Oligosaccharides |
Discussion Leader: R.L. Halcomb
Thursday, 7:30 p.m.
J.E. Thomas-Oates "Glycoconjugate structural analysis: a mass spectrometric
approach
C.A. Bush "Use of scalar and dipolar couplings in determining the
conformation of complex oligosaccharides "
T. Shantha Raju "Species Specific Variations and Crystal Structures of
Immunoglobulin Glycoforms "
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