Sunday, June 17th |
Evening | Total Synthesis from Carbohydrate Materials (Geert-Jan Boons, UGa, USA) |
7:15 - 7:30 | Introduction, Eric Toone |
7:30 - 8:30 | Jacques Van Boom Lieden, The Netherlands Recent Advances in the Design of Biologically Relevant Molecules Based on Sugars |
8:30 - 9:30 | José Marco-Contelles, CSIC, Spain Strategies and Tactics for the Synthesis of Enantiomerically Pure Medium-Sized Rings from Carbohydrates |
Monday, June 18th |
Morning | X-Ray Studies of Carbohydrate Structure (David Bundle, U. Alberta, Canada) |
9:00 - 10:00 | Jim Naismith, St. Andrews, Scotland Two New Enzyme Mechanisms of Carbohydrate Synthesis |
10:00 - 10:30 | Coffee, Conference Photograph |
10:30 - 11:30 | Bill Weiss, Stanford, USA Structural Basis of Carbohydrate Recognition by C-type Lectins |
11:30 - 12:30 | Jim Rini, Toronto, Canada X-Ray Crystal Structure of Rabbit N Acetylglucosaminyltransferase I, A Key Enzyme in the Biosynthesis of N-Linked Glycans |
Evening | C-Glycosides Synthesis (Peter Seeberger, MIT, USA) |
7:30 - 8:30 | Robert Linhardt, U of Iowa, USA Synthesis of C-Glycosides of Ulosonic Acids |
8:30 - 9:30 | Richard Franck, Hunter College, USA The Practical Synthesis of C-Glycosides via The Ramberg-Bäcklund Reaction |
Tuesday, June 19th |
Morning | NMR (Alan Bush, UMBC, USA) |
9:00 - 10:00 | Jim Prestegard, U. of Georgia, USA Carbohydrates and Carbohydrate Binding Proteins: Structure and Dynamics from Residual Dipolar Couplings |
10:00 - 10:30 | Coffee |
10:30 - 11:10 | Carole Bewley, NIDDK, USA Solution Structure of a Cyanovirin-N:Mana1,2Mana Complex: Structural Basis for Selective Nanomolar Binding to Man-8 D1D3, Man9 and the HIV Envelope Protein GP120 |
11:10 - 11:50 | Joe Barchi NCI, USA Using Sugar Pucker to Your Advantage in Designing Nucleoside Therapeutics |
11:50 - 12:30 | Jesús Jiménez-Barbero CSIC, Spain Investigations of the Interactions Between Carbohydrates and Proteins: A Three Dimensional View by Using NMR Spectroscopy |
Evening | Glycomimetics (Jackie Gervay-Hague, University of Arizona) |
7:30 - 8:15 | Prabhat Arya NRC, Canada Artificial Glycopeptides- Rapid Access to New Chemical Probes for Glycobiology |
8:15 - 9:00 | Phaedria St. Hilaire, Carlsberg, Denmark SIALOPEPTIDES: An Investigation of their Mimicry of Siglec Binding Oligosaccharides |
9:00 - 9:45 | Thisbe Lindhorst, Kiel, Germany Mimicking Complex Carbohydrates |
Wednesday, June 20th |
Morning | Biophysical Studies of Carbohydrate Structure (Eric Toone, Duke U., USA) |
9:00 - 10:00 | Anne Dell, Imperial College, UK Carbohydrate Mass Spectrometry: the Post-Genomics Era |
10:00 - 10:20 | Coffee |
10:30 - 11:10 | David Brant, UC Irvine, USA Shapes and Motions of Polysaccharides |
11:10 - 11:50 | Deborah Leckband, UIUC, USA Measurements of Carbohydrate Interaction Forces |
11:50 - 12:30 | Carolyn Bertozzi UC Berkeley, USA A Small Molecule Switch for Polysialic Acid Expression on Neurons and Tumor Cells
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Evening | Synthesis of Novel Carbohydrate Structures (David Baker, U Tenn, USA) |
7:30 - 8:30 | Tomas Hudlicky, U. Florida, USA Synthesis and Properties of Novel Inositol Oligomers |
8:30 - 9:30 | Jose Garcia Fernandez, CSIC, Spain Multivalent Cyclooligosaccharides: Molecular inclusion and Lectin Binding Properties
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Thursday, June 21st |
Morning | Glycobiology (Mario Pinto, Simon Fraser, Canada) |
9:00 - 10:00 | Peter Petillo, UIUC, USA The Synthesis and Structure of Linear Carbohydrates |
10:00 - 10:30 | Coffee |
10:30-11:10 | Ron Eby, Wyeth Lederle Vaccines, USA Glycoconjugates As Vaccines |
11:10-11:50 | Birte Svensson, Carlsberg, Denmark Substrate Recognition, Subsite Engineering and Domain Interactions in Starch Degrading-Enzymes |
11:50-12:30 | Jeremy Carver, Glycodesign "Glycotherapeutics" |
Evening | New Methods for Glycosylation (Nikki Burkhalter, Wyeth-Lederle Vaccines) |
7:30 - 8:30 | David Gin UIUC, USA Exploring New Glycosylation Methods |
8:30 - 9:30 | Todd Lowary Ohio State, USA 2,3-Anhydrosugar Derivatives as Glycosylating Agents |