| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | New Synthetic Methods |
| Discussion Leader: Jacquelyn Gervay-Hague |
| Chair's Welcome
Conference Business |
| 7:45 pm | Invited Talk: William Roush
"Recent Studies on the Synthesis of 2-Deoxy-?-Glycosides: Applications in the Synthesis of Natural Products" |
| 8:15 pm | Discussion |
| 8:20 pm | Selected Short Talk: George O'Doherty
"De Novo Enantioselective Synthesis of Mono-, Di-, and Oligosaccharides via Catalytic Reactions" |
| 8:35 pm | Discussion |
| 8:40 pm | Selected Short Talk: Alexei Demchenko
"Oxazolyl and Thiazoyl Thioglycosides as Novel Versatile Glycosyl Donors" |
| 8:55 pm | Discussion |
| 9:00 pm | Chair's Reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | GROUP PHOTO SESSION |
| 9:00 am - 11:00 pm | Carbohydrate-Based Vaccines |
| Discussion Leader: Jay Heron |
| 9:00 am | Invited Talk: Istvan Toth
"Liposaccharides for Drug and Vaccine Delivery" |
| 9:30 am | Discussion |
| 9:35 am | Selected Short Talk: Rina Saksena
"Preparation of a Conjugate Vaccine for Cholera from Synthetic Fragments of the O-PS of Vibrio cholerae 0;1" |
| 9:50 am | Discussion |
| 9:55 am | Invited Talk: Peter Seeberger
"Automated Synthesis of Oligosaccharide Antigens to Enable Vaccine Development: An Anti-Toxin Malaria Vaccine Candidate and Other Examples" |
| 10:25 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 12:30 pm | Carbohydrates in Disease |
| Discussion Leader: Elizabeth Higgins |
| 11:00 am | Invited Talk: Mark von Itzstein
"Carbohydrates in Disease and Glycotherapeutic Discovery" |
| 11:30 am | Discussion |
| 11:35 am | Selected Short Talk: Zhongwu Guo
"Glycoengineering Cancer for Its Selective Immunotherapy" |
| 11:50 am | Discussion |
| 11:55 am | Invited Talk: Kevin Rice
"Evolution of Glycotargeted Gene Delivery Systems" |
| 12:25 am | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm | FREE TIME |
| 4:30 pm | Poster Session #1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Carbohydrate Chemical and Biological Diversity |
| Discussion Leader: Geert-Jan Boons |
| 7:30 pm | Invited Talk: Robert Rosenberg
"The Biology and Chemistry of Heparan Sulfate Proteoglycans" |
| 8:00 pm | Discussion |
| 8:05 pm | Selected Short Talk: Robert Kerns
"Strategy for Preparing Saccharides that Display Unique Protein-Binding Profiles" |
| 8:20 pm | Discussion |
| 8:25 pm | Selected Short Talk: Nathalie Karst
"Sulfo-protected Sugars: A New Approach Toward Glycosaminoglycan Synthesis" |
| 8:40 pm | Discussion |
| 8:45 pm | Invited Talk: Carlitto Lebrilla
"The Role of Mass Spectrometry in Understanding Oligosaccharide Diversity" |
| 9:15 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 pm | Carbohydrate Bioengineering |
| Discussion Leader: Tom Chang |
| 9:00 am | Invited Talk: George Wang
"Following Biosynthetic Pathways to Make Oligosaccharides and Carbohydrate Vaccines" |
| 9:30 am | Discussion |
| 9:35 am | Invited Talk: Yong Li
"Unnatural Macrolides, Natural Sugars and New Antibiotics" |
| 10:05 am | Discussion |
| 10:20 am | Invited Talk: David Hakes
"In-vitro Enzymatic Modifications of Glycans to Improve Pharmaceutical Performance of Glycoprotein Drugs" |
| 10:40 | Discussion |
| 10:45 | Coffee Break |
| 11:00 am - 12:30 pm | Carbohydrate Enzymology |
| Discussion Leader: Eric Toone |
| 11:00 am | Invited Talk: James Coward
"Carbohydrate Synthesis and Organofluorine Chemistry: Applications in Mechanistic Enzymology" |
| 11:30 am | Discussion |
| 11:35 am | Selected short Talk: David Stapleton
"AMPK??-Subunit Targets Metabolic Stress-Sensing to Glycogen" |
| 11:50 am | Discussion |
| 11:55 am | Invited Talk: Birte Svensson
"Structure-Based Engineering of Protein Recognition and Carbohydrate Conversion by Amylolytic Enzymes" |
| 12:25 | Discussion |
| 12:30 pm | Lunch |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Carbohydrates and Enzymes |
| Discussion Leader: Don Kiely |
| 7:30 pm | Invited Talk: Ben Davis
"Sugars and Enzymes" |
| 8:00 pm | Discussion |
| 8:05 pm | Selected Short Talk: Nicola Pohl
"Chemical Tools for Carbohydrate Activity Profiling" |
| 8:20 pm | Discussion |
| 8:25 pm | Invited Talk: Laura Kiessling
" Understanding and Inhibiting Galactofuranose Residue Incorporation" |
| 8:55 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 pm | NSF and
Carbohydrate Synthesis |
| Discussion Leader: David Baker |
| 9:00 am | Invited Talk: George Rubottom
"Funding Opportunities at NSF" |
| 9:30 am | Discussion |
| 9:35 am | Invited Talk: Randy Mootoo
"Synthesis of Probes for Carbohydrate Mediated Mechanisms" |
| 10:05 am | Discussion |
| 10:10 | Invited Talk: Zbigniew Witczak
"New Frontiers in Carbohydrate Based Drug Development: Thiodisaccharides -Emerging Concepts and Potential Therapeutic Applications" |
| 10:40 | Discussion |
| 10:45 | Coffee Break |
| 11:00 am - 12:30 pm | Carbohydrate Synthesis |
| Discussion Leader: Alosius Siriwardena |
| 11:00 am | Invited Talk: András Lipták
"Sugar C-Sulfonic Acids. Their Synthesis and Some Preliminary Results" |
| 11:30 am | Discussion |
| 11:35 am | Invited Talk: Ulf Nilsson
"Synthetic Galectin Inhibitors" |
| 12:05 pm | Discussion |
| 12:10 pm | Conference Business
1. Select Vice-Chair 2005
2. Evaluation Forms |
| 12:30 pm | Lunch |
| 1:30 pm | FREE TIME |
| 4:30 pm | Poster Session #3 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Computational Chemistry and NMR |
| Discussion Leader: Todd Lowary |
| 7:30pm | Invited Talk: Robert Woods
"Computational Carbohydrate Chemistry Water Water Everywhere" |
| 8:00 pm | Discussion |
| 8:05 pm | Selected Short Talk: Mark Pekzuh
"Septanose Carbohydrates: Preparation and Conformational Analysis" |
| 8:20pm | Discussion |
| 8:25 pm | Invited Short Talk: Daron Freeberg
"Distinct Three-Dimensional Structures of??- and??-Lactose from New NMR Measurements - Implications for Enzyme Specificity" |
| 8:40 pm | Discussion |
| 8:45 pm | Invited Talk: Anthony Serianni
"Oligosaccharide Conformation via Redundant 13C-13C and 13C-1H Scalar Coupling Analysis" |
| 9:15 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Molecular Scaffolds and
Polyvalent Interactions |
| Discussion Leader: Amit Basu |
| 9:00 am | Invited Talk: George Fleet
"Sugar Scaffolds and/or Sugar Mimics from Sugar Lactones" |
| 9:30 am | Discussion |
| 9:35 am | Invited Talk: Horst Kessler
"Sugars and Sugar Amino Acids as Structural Templates for Bioactive Peptidomimetics" |
| 10:05 am | Discussion |
| 10:20 am | Invited Talk: Eric Toone
"The Molecular Basis of Affinity in Protein-Carbohydrate Interactions" |
| 10:40 am | Discussion |
| 10:45 | Coffee Break |
| 11:00 am - 12:30 pm | Molecular Scaffolds and
Polyvalent Interactions |
| Discussion Leader: Laura Kiessling |
| 11:00 am | Invited Talk: Mary Cloninger
"Using Dendrimers to Study Multivalent Protein-Carbohydrate Interactions" |
| 11:30 am | Discussion |
| 11:35 am | Selected short Talk: Alshakim Nelson
"Carbohydrate-Based Glycodendrimers for Multivalent Display of Sialic Acid" |
| 11:50 am | Discussion |
| 11:55 am | Invited Talk: René Roy
"New Trends in the Amplification of Carbohydrate Protein Interactions" |
| 12:30 pm | Lunch |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Molecular Scaffolds and
Polyvalent Interactions |
| Discussion Leader: Jennifer Koviach |
| 7:30 pm | Conference Business
Announcement of Vice-Chair for 2005 |
| 7:45 pm | Invited Talk: Randy Halcomb
"Synthesis of Glycopeptides and Their Mimetics" |
| 8:15 pm | Discussion |
| 8:20 pm | Selected Short Talk: Katja Michael
"Convergent Synthesis of N-Glycopeptides with Minimal Aspartimide Formation" |
| 8:35 pm | Discussion |
| 8:40 pm | Invited Talk: Robin Polt
"Glycopeptide Interactions with Membranes: Rationale for BBB Transport and Analgesia of Glycosylated Enkephalins" |
| 9:10 pm | Discussion |
| 9:15 pm | Chair 2005 Reception |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
