SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Carbohydrate Synthesis I |
| Discussion Leader: Paul Murphy (University College Dublin, Ireland) |
7:40 pm - 8:05 pm | Todd Lowary (University of Alberta, CANADA)
"Studies on the synthesis and biochemistry of bacterial furanosides" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Shino Manabe (RIKEN, JAPAN)
"Novel glycosyl donors for 1,2-cis glycosylation of amino sugars and development of rapid oligosaccharide synthesis" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Timor Baasov (Technion, Haifa, ISRAEL)
"Designer aminoglycosides: the race to develop improved antibiotics and compounds for the treatment of human genetic diseases" |
9:15 pm - 9:25 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Glycobiology I |
| Discussion Leader: Lai-Xi Wang (University of Maryland, USA) |
9:00 am - 9:25 am | Carolyn Bertozzi (University of California, Berkeley, USA)
"Imaging the glycome" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:45 am | Short Talk: Mary O'Reilly (Scripps Research Institute, USA)
"A self-assembling, multivalent ligand for CD22 facilitates the investigation of endocytic and recycling pathways" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Gurdyal Besra (University of Birmingham, UK)
"Tuberculosis: a balanced diet of lipids and carbohydrates" |
10:15 am - 10:25 am | Discussion |
10:25 am | Coffee Break / Group Photo |
10:50 am - 11:00 am | Short Talk: Chris Cairo (University of Alberta, CANADA)
"Glycosphingolipid and sphingomyelin mimics for membrane enzymology" |
11:00 am - 11:05 am | Discussion |
11:05 am - 11:15 am | Short Talk: Angelyn Larkin (Massachusetts Institute of Technology, USA)
"Biosynthetic enzymes in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Short Talk: Gerd Wagner (University of East Anglia, UK)
"Towards a general glycosyltransferase assay" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Alisdair Boraston (University of Victoria, CANADA)
"Non-catalytic recognition of glycans by the modules of carbohydrate-active enzymes" |
12:00 pm - 12:10 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Renewable Resources |
| Discussion Leader: Warren Wakarchuk (NRC, CANADA) |
7:30 pm - 7:55 pm | Bernard Henrissat (AFMB, Marseilles, FRANCE)
"Carbohydrate-active enzymes: what do a thousand complete genome sequences tell us?" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Gabrielle Potocki-Veronese (LISBP, Toulouse, FRANCE)
"Using functional metagenomics for the discovery of novel enzymes specific to plant fiber degradation" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:50 pm | Short Talk: Wei Huang (University of Maryland, USA)
"Chemoenzymatic synthesis of a class of novel N-glycan clusters for functional glycomics" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Harry Brumer (KTH, Stockholm, SWEDEN)
"Plant xyloglucans: enzymology of degradation and re-arrangment" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Structural Biology |
| Discussion Leader: Allen Bush (University of Maryland, USA) |
9:00 am - 9:25 am | Jim Prestegard (CCRC, Athens, USA)
"Isotope labeling strategies and new NMR observables for the characterization of protein-carbohydrate complexes" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:45 am | Short Talk: Latifa Elantak (CNRS-IMM, FRANCE)
"Structural basis of galectin-1 dependent pre-B cell receptor activation" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Thilo Stehle (Tübinger Universitäts Nachrichten - TUN, GERMANY)
"Structural analysis of carbohydrate receptor recognition by viruses" |
10:15 am - 10:25 am | Discussion |
10:25 am | Coffee Break |
10:50 am - 11:15 am | Robert Ben (University of Ottawa, CANADA)
"Is rational design of functional C-linked antifreeze glycoproteins possible?" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:35 am | Short Talk: Janos Nadas (Ohio State University, USA)
"Computational structure activity relationship studies on the CD1d/glycolipid/TCR complex using AMBER and AUTODOCK" |
11:35 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Ken Ng (University of Calgary, CANADA)
"Structural basis of carbohydrate recognition in Clostridium difficile toxins" |
12:05 pm - 12:15 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Carbohydrates in Industry |
| Discussion Leader: Gerd Wagner (University of East Anglia, UK) |
7:30 pm - 7:55 pm | Stewart Campbell (Ancora Pharmaceuticals, USA)
"Synthetic approaches to carbohydrate antigens" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Steffen Goletz (Glycotope, Berlin, GERMANY)
"GlycoOptimisation of antibody and protein based biopharmaceuticals" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:50 pm | Short Talk: Yann Chevolot (INL-CNRS, FRANCE)
"DNA directed immobilisation of glycomimetics for biosensing applications" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Gavin Painter (IRL, NEW ZEALAND)
"Synthesis and biological activity of glycolipid immune modulators" |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Carbohydrate Synthesis II |
| Discussion Leader: George O'Doherty (West Virginia University, USA) |
9:00 am - 9:25 am | Koichi Fukase (Osaka University, JAPAN)
"Chemical glycobiology of self/non-self recognition" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:45 am | Short Talk: Srinivas Hotha (National Chemical Laboratory, INDIA)
"Stable alkyl glycosides as glycosyl donors" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Spencer Williams (University of Melbourne, AUSTRALIA)
"The role of 2,6-disubstituted benzoates in the synthesis of oligo-β-D-galactosides" |
10:15 am - 10:25 am | Discussion |
10:25 am | Coffee Break |
10:50 am - 11:15 am | Kwan Soo Kim (Yonsei University, KOREA)
"Development of new stereoselective glycosylation methods and their application to oligosaccharide synthesis" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:35 am | Short Talk: Rodrigo Andrade (Temple University, USA)
"Gem-dimethyl pentenyl glycosides: novel glycosylating agents and anomeric protecting groups" |
11:35 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Biao Yu (Shanghai Institute of Organic Chemistry, P.R. CHINA)
"New glycosylation protocols for the synthesis of complex glycoconjugates" |
12:05 pm - 12:15 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | Glycobiology II |
| Discussion Leader: Nicola Pohl (Iowa State University) |
7:30 pm - 7:55 pm | Jinshi Zhao (Chris Raetz - Duke University, USA)
"Lipid A modification systems in Gram-negative bacteria" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Chris Whitfield (University of Guelph, CANADA)
"Coupling glycosyltransferases to export machinery in the assembly of bacterial glycans" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:50 pm | Short Talk: Christine Szymanski (University of Alberta, CANADA)
"A new role for the bacterial N-linked protein glycosylation pathway" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | David Bundle (University of Alberta, CANADA)
"Supramolecular heterobifunctional ligand-protein complexes: a strategy for enhancing drug efficacy" |
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Young Glycoscientists |
| Discussion Leader: Rob Woods (CCRC, Athens, USA) |
9:00 am - 9:20 am | Mario Feldman (University of Alberta, CANADA)
"Bacterial protein glycosylation systems and their promising applications in conjugate vaccine design" |
9:20 am - 9:25 am | Discussion |
9:25 am - 9:45 am | Lara Mahal (University of Texas, Austin, USA)
"Studying dynamic glycosylation in signaling with new tools" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:10 am | Kevin Yarema (Johns Hopkins University, Baltimore, USA)
"Design of SCFA-hexosamine analogs for metabolic glycoengineering and cancer therapy" |
10:10 am - 10:15 am | Discussion |
10:15 am | Coffee Break |
10:50 am - 11:10 am | Daniel Werz (Göttingen University, GERMANY)
"Palladium-mediated reactions with carbohydrates" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:35 am | Mark Nitz (University of Toronto, CANADA)
"Protecting-group-free methods for glycoside formation" |
11:35 am - 11:40 am | Discussion |
11:40 am - 12:00 pm | Jeroen Codee (Leiden University, THE NETHERLANDS)
"Stereoselective synthesis of anionic oligosaccharides" |
12:05 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Carbohydrate Engineering |
| Discussion Leader: Xi Chen (University of California, Davis, USA) |
7:30 pm - 7:55 pm | T.H. Van Kuppevelt (Rahboud Univ. Nijmegen, THE NETHERLANDS)
"Human single chain antibodies to detect and locate glycosaminoglycan motives in tissues" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Peng George Wang (Ohio State University, Columbus, USA)
"Biosynthesis and bioengineering of bacterial polysaccharides" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:50 pm | Short Talk: Allen Bush (University of Maryland, USA)
"Comparative molecular characterization of Streptococcus oralis coaggregation receptor polysaccharides and Streptococcus pneumoniae capsular polysaccharides" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Jian Liu (University of North Carolina, Chapel Hill, USA)
"Developing an enzyme-based approach to synthesize heparan sulfate" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |