SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Chemical Glycobiology |
| Discussion Leader: Chris Cairo (University of Alberta) |
7:40 pm - 8:05 pm | Amit Basu (Brown University)
"Chemical Glycobiology of Pollen Tube Extension" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | David Jakeman (Dalhousie U)
"Carbohydrate phosphonates, multi-functional enzyme probes"
|
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Valentin Wittmann (University of Konstanz)
"Two color glycan labeling of live cells by a combination of Diels-Alder and click chemistry"
|
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | Poster Highlight Talk: Roger Ashmus (University of Alberta)
"Progress towards understanding the biosynthesis of phosphoramidates in Campylobacter jejuni"
|
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Lessons from the CFG (Consortium for Functional Glycomics) |
| Discussion Leader: Joe Barchi (National Cancer Institute at Frederick) |
9:00 am - 9:20 am | Pamela Marino (National Institute of General Medical Sciences)
"Challenges of an Omic's Era - seeking partners and finding opportunities" |
9:20 am - 9:25 am | Discussion |
9:25 am - 9:50 am | James Paulson (Scripps Research Institute)
"Decoding the glycome: A central paradigm of the CFG"
|
9:50 am - 10:00 am | Discussion |
10:00 am - 10:25 am | Group Photo / Coffee Break |
10:25 am - 10:50 am | Anne Dell (Imperial College)
"Glycosylation of mouse and human immune cells: insights emerging from glycomics analysis"
|
10:50 am - 11:00 am | Discussion |
11:00 am - 11:25 am | David Smith (Emory U.)
"Application of Glycan Microarrays to Deciphering the Structure and Function of the Human Glycome"
|
11:25 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Rahul Raman (MIT)
"Informatics for Glycomics at the CFG"
|
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Brief Talk: Wesley Zandberg (Simon Fraser University of Konstanz)
"Trojan horse inhibition of glycosyltransferases in cells: controlling cell surface expression of glycans" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I (1-55) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Carbohydrate Synthesis and Biosynthesis |
| Discussion Leader: Jennifer Koviach-Cote (Bates College) |
7:30 pm - 7:55 pm | Hung-wen (Ben) Liu (University of Texas)
"Exploiting sulfur carrier proteins from primary metabolism for 2-thiosugar biosynthesis"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Todd Lowary (University of Alberta)
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:50 pm | Short Talk: Matthew Pratt (University of Southern California)
"Development of a highly selective metabolic chemical reporter of O-GlcNAc modifications"
|
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Linda Hsieh-Wilson (Cal Tech)
"Using Chemistry to Discover Carbohydrate Mechanisms in Biology and Disease"
|
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Carbohydrate Immunology and Immunotherapy |
| Discussion Leader: Jeff Gildersleeve (National Cancer Institute) |
9:00 am - 9:25 am | Peter Andreana (University of Toledo)
"PS A1 as a Covalent Adjuvant in Immune Stimulation"
|
9:25 am - 9:35 am | Discussion |
9:35 am - 9:45 am | Short Talk: Saddam Muthana (National Cancer Institute, Frederick)
"Studying immunogenicity of blood group antigens and developing a new method for blood typing"
|
9:45 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Kate Rittenhouse-Olson (University of Buffalo)
"Unique immunization strategies for Thomsen Friedenreich Antigen"
|
10:15 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
| Discussion Leader: Isaac Krauss (Brandeis University) |
10:55 am - 11:05 am | Short Talk: Roberto Adamo (Novartis Vaccines and Diagnostics)
"Site selective conjugation at tyrosines on CRM197 as a general approach to well-defined conjugate vaccines"
|
11:05 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Horst Kunz (University of Mainz)
"Synthetic Antitumor Vaccines - an Interplay of Carbohydrate and Peptide Antigen Structures"
|
11:35 am - 11:45 am | Discussion |
11:45 am - 11:50 am | Poster Highlight Talk: Nathaniel Schocker (University of Texas El Paso)
"Potential use of synthetic alpha-galactosyl and alpha-rhamnosyl containing glycotopes of the parasite Trypanosoma cruzi as new diagnostic biomarkers for Chagas Disease"
|
11:50 am - 11:55 am | Poster Highlight Talk: Cristina Zamora (Tufts University)
"Fluorogenic sialic acid glycosides for quantification of sialidase activity upon natural substrates"
|
11:55 am - 12:20 pm | Lai-Xi Wang (University of Maryland)
"Synthetic Carbohydrate Antigens for HIV Vaccine Design"
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II (56-106) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Glycans and Natural Products |
| Discussion Leader: Daniel Werz (University of Goettingen) |
7:30 pm - 7:55 pm | Jurgen Rohr (University of Kentucky)
"Enzymatic Total Syntheses of TDP-deoxysugars and Their Use for Studying Glycosyltransfer Reactions of Antitumor Antibiotic Biosyntheses"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Rodrigo Andrade (Temple University)
"Total Synthesis and Biological Evaluation of Desmethyl Macrolide Antibiotics"
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:50 pm | Short Talk: Thomas Beale (University of Toronto)
"Regioselective glycosylations of natural products using borinic acid catalysts"
|
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:10 pm | Clay Bennett (Tufts University)
"Reagent controlled chemical glycosylation"
|
9:10 pm - 9:25 pm | Isaac Krauss (Brandeis University)
"Directed Evolution of Carbohydrate Clusters in Design of HIV Vaccine Candidates"
|
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Molecular Structure and Recognition in Glycan Drug Design |
| Discussion Leader: Susanne Striegler (University of Arkansas) |
9:00 am - 9:25 am | Robert Woods (University of Georgia)
"Computational screening of virtual glycan arrays: a new tool for specificity prediction and validation"
|
9:25 am - 9:35 am | Discussion |
9:35 am - 9:45 am | Short Talk: France Isabelle Auzanneau (University of Guelph)
"Synthesis of LeALeX oligosaccharide fragments and molecular modeling of the LeALeX Tumor Associated Carbohydrate Antigen"
|
9:45 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Dev Arya (Clemson University)
"Shape Recognition of Nucleic Acids by Carbohydrates"
|
10:15 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
| Discussion Leader: Yann Chevolot (Institut des Nanotechnologie, Lyon) |
10:55 am - 11:05 am | Short Talk: Alexander Titz (University of Konstanz)
"Discovery of two classes of potent and drug-like glycomimetic inhibitors of Pseudomonas aeruginosa LecB with distinct binding modes"
|
11:05 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Chang-Chun Lin (University of Calgary)
"Targeting Clostridium Difficile Toxins: Challenges and Recent Developments"
|
11:35 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Short Talk: Miao He (Emory University)
"Using an N-linked tetrasaccharide as a biomarker for the diagnosis of ALG1-CDG (CDG-lk)"
|
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Short Talk: Danielle Dube (Bowdoin College)
"Chemical tools to discover and target Helicobacter pylori's glycoproteins"
|
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Short Talk: Alexandre Driguez (Sanofi Aventis)
"Synthesis of new and non-natural specific FGFR4-agonists heparin octasaccharides"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session III (All posters) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Glycosylation and Anomeric Chemistry |
| Discussion Leader: Alexei Demchenko (University of Missouri) |
7:30 pm - 7:55 pm | Scott Rychnovsky (University of California Irvine)
"Reactivity next to heteroatoms: anomeric effects beyond carbohydrates"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Toshiki Nokami (Tottori University)
"Electrochemistry as an enabling tool for glycosylation"
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:50 pm | Short Talk: Takayuki Furukawa (Wayne State University)
"Development of a cation clock reaction for determining relative kinetics of glycosylation reactions" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Suvarn Kulkarni (Indian Institute of Technology, Bombay)
"Expeditious synthesis of bacterial glycoconjugates"
|
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
9:00 am - 12:30 pm | Glycan and Glycoconjugate Synthesis: Enzymes and Beyond |
| Discussion Leader: Eugene Cioffi (University of South Alabama) |
9:00 am - 9:25 am | Kelley Moremen (University of Georgia)
"Production and use of mammalian glycosylation enzymes for enzymatic and structural studies"
|
9:25 am - 9:35 am | Discussion |
9:35 am - 9:45 am | Short Talk: Luigi Panza (University of Piemonte)
"Synthetic approaches to glycosphingolipids"
|
9:45 am - 9:50 am | Discussion |
9:50 am - 10:15 am | Xi Chen (University of California Davis)
"Chemoenzymatic synthesis of carbohydrates and glycoconjugates"
|
10:15 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
| Discussion Leader: Yasuhiro Kajihara (Osaka University) |
10:55 am - 11:05 am | Short Talk: Xuechen Li (University of Hong Kong)
"New methods in glycopeptides/glycoprotein synthesis"
|
11:05 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Robert Linhardt (Renssalear Polytechnic University)
"Chemoenzymatic synthesis of heparins"
|
11:35 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Short Talk: Srinivas Hotha (Indian Institute of Science Education and Research, Pune)
"Oligoarabinans by gold catalyzed glycosylations"
|
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Short Talk: Steven Sucheck (University of Toledo)
"Mycobacterium tuberculosis GIgE: Structure, mechanism and inhibition of an essential maltosyltransferase"
|
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Short Talk: Xinyu Liu (University of Pittsburgh)
"New tactics and strategies in oligosaccharide assembly"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session IV (All posters) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Nanomaterials, Sensors and Diagnostics |
| Discussion Leader: Suri Iyer (Georgia State University) |
7:30 pm - 7:55 pm | Theresa Reineke (University of Minnesota)
"Sugar-coated nanocomplexes: designed block copolymers for therapeutic delivery"
|
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Xuewei Liu (Nanyang Technological University)
"Glycosciences: From Synthetic Methods to Glycobiology"
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:50 pm | Short Talk: Cornelius Boerkoel (National Institutes of Health)
"Detection of glycosylation abnormalities among individuals with undiagnosed diseases: The NIH Undiagnosed Disease Program experience"
|
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Nicola Pohl (Indiana University)
"Challenges in Carbohydrate Library Synthesis"
|
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |