Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff / In Memoriam: Derek Horton (1932-2015), by Todd Lowary (University of Alberta) |
7:40 pm - 9:30 pm | Defining and Understanding Glycomes |
| Discussion Leader: Amit Basu (Brown University, USA) |
7:40 pm - 8:05 pm | Carlito Lebrilla (University of California, Davis, USA) "Rapid Throughput Characterization of Oligosaccharides and Carbohydrates Through Advanced Analytical Methods" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Hans Lin (Academia Sinica, Taiwan) "Development of In-Vivo Tagging Method to Characterize Helicobacter pylori Glycolipids" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Lara Mahal (New York University, USA) "Sweet RNA: MicroRNA Control of Glycosylation" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | Poster Preview |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Chemical Glycosylation and Beyond |
| Discussion Leaders: Shang-Cheng Hung (Academia Sinica, Taiwan) and Stefan Oscarson (University College Dublin, Ireland) |
9:00 am - 9:25 am | Biao Yu (Shanghai Institute of Organic Chemistry (CAS), China) "Exploring a Universal Glycosylation Protocol" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Cristina De Meo (Southern Illinois University, Edwardsville, USA) "Effects
of Remote Picoloyl Substituents in Chemical Sialylation" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:20 am | Selected from Poster Abstracts: Nicole Snyder (Davidson College, USA) "New Routes for the Synthesis of Carbohydrate Porphyrin (CPCs), Carbohydrate Bacteriochlorin (CBCs) and Carbohydrate Phthalocyanine (CPcCs) Conjugates" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:30 am | Poster Preview |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:25 am | David Crich (Wayne State University, USA) "Synthesis of Sialic Acid Glycosides and Their Derivatives" |
11:25 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Zhongwu Guo (Wayne State University, USA) "Synthetic and Biological Studies of Cell Surface GPIs and GPI-Anchored Proteins" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Selected from Poster Abstracts: Luigi Lay (University of Milan, Italy) "Glycoconjugates of Carba Oligomers from Neisseria Meningitidis A Capsular Polysaccharide." |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | Poster Preview |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Chemical Glycobiology |
| Discussion Leader: Danielle Dube (Bowdoin College, USA) |
7:30 pm - 7:55 pm | Carmen Galan (University of Bristol, United Kingdom) "Novel Glyco Nano-Tools for Cell Imaging" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:15 pm | Selected from Poster Abstracts: Michael Boyce (Duke University School of Medicine, USA) "Cell Signaling Through O-GlcNAc "Reader" Proteins" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Suzanne Walker (Harvard Medical School, USA) "Mapping Cell Envelope Networks Using Small Molecules" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Geert-Jan Boons (University of Georgia, USA) "Functional Glycomics Through Chemical Synthesis" |
9:20 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Frontiers in Carbohydrate Synthesis |
| Discussion Leaders: France-Isabelle Auzanneau (University of Guelph, Canada) and Susanne Striegler (University of Arkansas, USA) |
9:00 am - 9:25 am | Shino Manabe (Riken, Japan) "Pyranosides with 2,3-trans Carbamate Group: Exocyclic Cleavage or Endocyclic Cleavage?" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:45 am | Selected from Poster Abstracts: Ratmir Derda (University of Alberta, Canada) "Genetically-Encoded Fragment-Based Discovery of Glycopeptide Ligands for Carbohydrate-Binding Proteins" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:15 am | George O'Doherty (Northeastern University, USA) "De Novo Approach to Carbohydrates" |
10:15 am - 10:25 am | Discussion |
10:25 am - 10:35 am | Selected from Poster Abstracts: Hongzhi Cao (Shandong University, China) "Diversity-Oriented Chemoenzymatic Synthesis of Alfa-Dystroglycan O-Mannose Glycans" |
10:35 am - 10:40 am | Discussion |
10:40 am - 11:10 am | Coffee Break |
11:10 am - 11:20 am | Selected from Poster Abstracts: Reko Leino (Åbo Akademi University, Finland) "Conformational Study of Homoallylic Polyol Derived from D-Mannose" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Srinivas Hotha (Indian Institute of Science Education and Research, India) "Gold Catalysis for the Chemical Mycobacteriology" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Selected from Poster Abstracts: Suvarn Kulkarni (Indian Institute of Technology Bombay, India) "Synthesis of Trehalose Containing Glycolipids
and Oligosaccharides from Mycobacteria" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Selected from Poster Abstracts: Steven Sucheck (The University of Toledo, USA) "Synthesis of Substrate and Transition State Inhibitors of S. coelicolor GlgEI-V279S" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Wonders of the Bacterial World |
| Discussion Leaders: Nikki Pohl (Indiana University, USA) and Peter Andreana (University of Toledo, USA) |
7:30 pm - 7:55 pm | Robert Field (John Innes Centre, United Kingdom) "Euglena gracilis Has Unexpected Capabilities in Carbohydrate and Natural Product Biochemistry" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:15 pm | Selected from Poster Abstracts: Jerry Troutman (University of North Carolina at Charlotte, USA) "Colanic Acid Biosynthesis Pathway Elucidation Using Fluorescent Bactoprenols" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:30 pm | Selected from Poster Abstracts: Neil Price (U.S. Department of Agriculture, USA) "Liamocins from Aureobasidium Pullulans with Antibacterial Activity Specific for Species of Streptococcus" |
8:30 pm - 8:35 pm | Discussion |
8:35 pm - 8:45 pm | Selected from Poster Abstracts: Mark Nitz (University of Toronto, Canada) "The Production and Inhibition of the Biofilm Related Poly-N-Acetylglucosamine Exopolysaccharide" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 8:55 pm | Poster Preview |
8:55 pm - 9:20 pm | Daniel Kahne (Harvard University, USA) "Lipopolysaccharide Transport and Assembly in Escherichia coli" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Design and Synthesis of Carbohydrates/Probes |
| Discussion Leaders: Steve Kolodziej (Pfizer, USA) and Xi Chen (University of California, Davis, USA) |
9:00 am - 9:25 am | Jeroen Codee (Leiden University, The Netherlands) "Conformation and Reactivity in Glycosylation Reactions" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Matthiew Sollogoub (Sorbonne University, France) "Site-Directed Modifications of Cyclodextrins for Hierarchical Self-Assembly" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:20 am | Selected from Poster Abstracts: Jiaoyang Jiang (University of Wisconsin-Madison, USA) "Addition and Removal of O-GlcNAc from C-terminal Domain of RNA Polymerase II Follow a Distributive Mechanism" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:30 am | Poster Preview |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:25 am | Daniel Varon Silva (Max Planck Institute of Colloids and Interfaces, Germany) "Glycosylphosphatidylinositols: A Complex and Active Bridge Between Proteins and Membranes" |
11:25 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Luigi Panza (University of Piemonte Orientale "A. Avogadro", Italy) "Synthesis and Biological Activity of Natural and Modified Glycosphingolipids" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Selected from Poster Abstracts: Marthe Walvoort (Massachusetts Institute of Technology, USA) "A Modular Approach to Phosphoglycosyltransferase Inhibitors Inspired by Tunicamycin" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | Poster Preview |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Translational Carbohydrate Chemistry |
| Discussion Leader: Robert Woods (University of Georgia, USA) |
7:30 pm - 7:55 pm | Michael Gelb (University of Washington, USA) "Newborn Screening for Lysosomal Storage Diseases: Carbohydrate Chemistry for Pediatric Medicine" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Vern Schramm (Albert Einstein College of Medicine, USA) "Transition State Analogues of N-Ribosyltransferases" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:50 pm | Selected from Poster Abstracts: James Janetka (Washington University School of Medicine, USA) "Bacterial Lectin Antagonists as Therapeutics: Development of Biaryl C-Mannosides" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Mark Von Itzstein (Griffith University, Australia) "Virus–Carbohydrate Interactions: Opportunities in Drug Discovery" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
9:00 am - 12:30 pm | Anti-Glycan Immunity |
| Discussion Leaders: Lai-Xi Wang (University of Maryland College Park, USA) and Yasuhiro Kajihara (Osaka University, Japan) |
9:00 am - 9:25 am | Nicolai Bovin (Shemyakin Institute of Bioorganic Chemistry, Russia) "Nature Operates by Molecular Patterns Rather than Molecules" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Peng George Wang (Georgia State University, USA) "Human Serum Anti-Carbohydrate Antibodies: Their Biogenesis, Biological Functions and Biomedical Application" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:20 am | Selected from Poster Abstracts: Chung-Yi Wu (Academia Sinica, Taiwan) "Immunogenicity Study of Globo H Analogues with Modification at the Reducing or Non-Reducing End of the Tumor Antigen" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
10:55 am - 11:05 am | Selected from Poster Abstracts: Dapeng Zhou (NanoCruise Pharmaceutical, China) "B Cell Recognition of Mucin Glycopeptides in Lung Cancer" |
11:05 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Joseph Barchi (National Cancer Institute, NIH, USA) "Glycopeptide Conjugates of Tumor-Associated Carbohydrate Antigens as Anticancer Agents" |
11:35 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Selected from Poster Abstracts: Thomas Boltje (Radboud University, The Netherlands) "A New Approach to Study the Sialobiology of Cancer" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Selected from Poster Abstracts: Corwin Nycholat (The Scripps Research Institute, USA) "Glycan Ligands for Targeting Siglecs on Immune Cells." |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Selected from Poster Abstracts: Daron Freedberg (Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, USA) "Significant Differences Between Calcium Free and Calcium Bound Sialic Acid Tetramer Structures" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Carbohydrates and Immunology: Partners for Life |
| Discussion Leader: Jeffrey Gildersleeve (National Cancer Institute, NIH, USA) |
7:30 pm - 7:55 pm | Xuefei Huang (Michigan State University, USA) "Development of Carbohydrate Based Anti-Cancer Vaccines" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:15 pm | Selected from Poster Abstracts: Adam Barb (Iowa State University, USA) "The Structural Role of Antibody N-Glycosylation in Receptor Interactions" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:30 pm | Selected from Poster Abstracts: Catherine Grimes (University of Delaware, USA) "Innate Immune Sensing of Bacterial Cell Wall Fragments" |
8:30 pm - 8:35 pm | Discussion |
8:35 pm - 8:45 pm | Introduction by Discussion Leader |
8:45 pm - 9:20 pm | Alexander M. Cruickshank Lecture: Laura Kiessling (University of Wisconsin - Madison, USA) "Us Versus Them: Distinguishing Humans from Microbes with Carbohydrates" |
9:20 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |