Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Enabling
Technologies for Functional Glycomics
7:40 pm - 8:05 pm
"Human Glycomics and Deciphering the Expression and Biological Recognition of Glycans"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"A Systems Approach to Carbohydrate Synthesis and Analysis"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Exploiting Anti-Glycan Immunity to Improve Cancer Care"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Glycosylation
and Synthetic Methodology
9:00 am - 9:25 am
"From Stereocontrolled Glycosylation to the Automated Oligosaccharide Synthesis"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Protecting Group Free Transformations of Reducing Sugars in Aqueous Solution"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Photo-Induced Glycosylation Reactions"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Synthesis of Glycoconjugates for Elucidation of Oligosaccharide Functions"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Stereoselective Synthesis of Kdo Glycoside"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Chemical Promoters for Controlling Selectivity in Glycosylation Reactions"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Chemistry on Protection and Functionalization of Free Sugars"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:55 pm
"Carbohydrate Recognition and Signaling in the Brain"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Human Influenza Virus Receptors"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Discovery of Host Cell Glycans Recognized by Bacterial Toxins"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Chemical Editing of the Glycocalyx to Influence Stem Cell Differentiation"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Enzymatic
and Chemoenzymatic Assembly of Glycans
9:00 am - 9:25 am
"Biosynthetic Studies of Oxetanocin A"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Mutant Glycosyltransferases and Hexosaminidases in the Synthesis of Advanced Glycomaterials"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Switching Enzyme Specificity from Phosphate to Resveratrol Glucosylation via Domain-Shift"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Discovering New Glycosidases Through Metagenomics and Gene Synthesis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Enzymatic Modular Assembly of Human Blood Antigens"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"New Insights into the Process and Function of Tryptophan C-Mannosylation Provided by Yeast Engineered to Perform This Protein Modification"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Synthesis and Application of Oligosaccharides Related to Plant Cell Wall Glycans"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Molecular Recognition in Protein-Carbohydrate Interactions
7:30 pm - 7:55 pm
"Microbial Lectins Binding to Lewis Glycotopes: Experimental and Computational Study"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Glycosyltransferases as Tools to Identify Cell Surface Lactosaminyl Glycans"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Chemoenzymatic Detection of Glycans: Methods and Applications"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Using Chemical Biology to Understand and Apply Protein O-Glycosylation"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Carbohydrate Vaccines and Glyco-Immunology
9:00 am - 9:25 am
"From Biologicals to Pharmaceuticals: A Medicinal Chemistry Approach to Carbohydrate-Conjugate Vaccines Against Streptococcus pneumoniae and Other Bacteria"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Glycopeptide Vaccines for Cancer Immunotherapy"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"An Entirely Carbohydrate-Recognizing Monoclonal Antibody"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Anti-Sialyl-Tn Monoclonal Antibody-Drug Conjugates (ADCs) Demonstrate Tumor Specificity In Vitro and In Vivo Antitumor Efficacy"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Precision Mapping of MUC1 Glycopeptides Expressed by Non-Small Cell Carcinoma"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Carbohydrate Involvement in Group B Streptococcus (GBS) Pathogenesis"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Structural
Chemistry and Biology of Carbohydrates
7:30 pm - 7:55 pm
"Computational and Biophysical Insight into Glycan Specificity: The Role of Entropy and Avidity"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Capsular Polysaccharides of the Nosocomial Pathogen Acinetobacter baumannii : Structure, Genetics, and Cleavage by Bacteriophages"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Can Advances in Mass Spectrometry Unlock the Mysteries of Glycans?"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Structures of Human O-GlcNAcase and Its Complexes Reveal a New Substrate Recognition Mode"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Synthetic
Probes for Deciphering Carbohydrate Functions
9:00 am - 9:25 am
"Synthetic Substrates for the Analysis of Glycan Processing Enzymes in the ER"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Synthesis of Designer Polysaccharides"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Synthesis of Rare Sugar AAT Containing Bacterial Glycoconjugates"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Carbohydrate Chemistry for RNA Interference: Synthesis, Structure and Biological Activity of Amide-Linked RNA"
11:20 am - 11:30 am
Discussion
11:30 am - 11:55 am
"Synthesis and Characterization of Specific Heparan Sulfate-Protein Interactions"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Palladium-Catalyzed Direct Stereoselective Synthesis of Deoxyglycosides from Glycals"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glycans
in Biotechnology and Medicine
7:30 pm - 7:55 pm
"Developing an Enzyme-Based Approach to Synthetize Glycosaminoglycans"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Nanomedicine Targeting Intracellular Glycoenzymes"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Glycosylation of a Subfragment Peptide of Type I Collagen"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Three Different Glycomimetic Drugs in Clinical Trials for Inflammatory Disorders and Cancer"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure