Sunday
2:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
7:40 pm - 8:05 pm
"NMR Studies of the 3D Structures of Sialic Acid Containing Oligo- and Polysaccharides"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Mapping and Manipulating the Glycoproteome"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Application of Bacterial CAZY Enzymes for the Synthesis of Glycoconjugates"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:25 am
"Saccharides, Pseudosaccharides and Their Mimetics"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Next-Generation Methods for the Synthesis of Oligosaccharides and Glycoconjugates"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"New Catalytic Methods for the Synthesis of Carbohydrates"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Group Photo / Coffee Break
10:55 am - 11:20 am
"Preactivation Strategy: A Powerful Approach to Glycan Synthesis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:55 am
"Stereoselective α-Glycosidation Using Bicyclic Sialic Acid Donors"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Catalytic Site-Selective Functionalization of Carbohydrates"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Enzymatic and Chemoenzymatic Synthesis
7:30 pm - 7:55 pm
"Recent Advance in Chemoenzymatic Synthesis of Glycoproteins"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Enzymatic Modular Assembly of Human Glycans"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Synthesis of Synthetic Lipid-Linked Oligosaccharides for In Vitro Glycoengineering of Proteins by a Cell-Free, Compartmentalized Multi-Enzyme Cascade"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Chemistry Around Transsialidases: Search for Novel Enzymes, Employment in Syntheses, and Inhibition Studies"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Machine-Assisted Synthesis
9:00 am - 9:25 am
"Automated Glycan Assembly of Polysaccharides: The Basis of Carbohydrate-Based Material Science"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Exploration of Carbohydrates in Human Immunity"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Assembly of Staphylococcus aureus WTA Heptamers with Aminohexanol Spacer on Ionic Liquid Support"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Streamlining the Chemoenzymatic Synthesis of Highly Complex Branched Glycans"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Total Synthesis of Resin Glycosides via Interrupted Pummerer Reaction Mediated Glycosylations"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"New Strategies for O-Glycosylation and Latent-Active Approaches to Oligosaccharide Synthesis New Strategies for O-Glycosylation and Latent-Active Approaches to Oligosaccharide Synthesis"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Nano- and Mesoscale Structuring in Reaction Solutions: Possibilities to Modulate the Outcome of Glycosylation and Other Reactions with Carbohydrate Derivatives"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
2:00 pm - 4:00 pm
Poster Session
4:00 pm - 6:00 pm
Biosynthesis and Degradation Enzymes
4:00 pm - 4:25 pm
"Leloir Glycosyltransferases for Chemical Production"
4:25 pm - 4:35 pm
Discussion
4:35 pm - 5:00 pm
"Structures of N. meningitidis CMP-Sialic Acid Synthetase with Substrates, and a Fungal Pathogen Effector Bound to Chitin"
5:00 pm - 5:10 pm
Discussion
5:10 pm - 5:20 pm
"Product-Oriented Chemical Surface Modification of Carbohydrate Active Enzymes"
5:20 pm - 5:25 pm
Discussion
5:25 pm - 5:50 pm
"Side-Chain Modifications of Mammalian GPI-Anchors"
5:50 pm - 6:00 pm
Discussion
6:00 pm - 7:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Carbohydrate-Based Prebiotics and Therapeutics
9:00 am - 9:25 am
"Next Generation Vaccines Made in Fermentation Free Chemoenzymatic Processes"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Novel Strategies for Carbohydrate Synthesis and Modification"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Structurally Defined Fluorogenic Probe Enables High-Throughput Screening of Inhibitors for Heparanase"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Glycoconjugates: Synthesis and the Latent Functions in Immune System"
11:20 am - 11:30 am
Discussion
11:30 am - 11:55 am
"The Effect of Marine Bioactive Polysaccharides on Gut Microbiota"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Preparation of Homogeneous Antibody-Drug Conjugate Through Glycan Remodeling"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glycoimmunology and Chemical Glycobiology
7:30 pm - 7:55 pm
"Woe and Weal: An Unexpected S-Glycosylation in Metabolic Glycan Labeling and Cysteine Profiling"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Immunogenic Properties of Structurally Diverse Streptococcal Capsular Polysaccharides"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Glycosylation Immunological Effects on Human Biodevices"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Human and Microbial Glycomes
9:00 am - 9:25 am
"Interactions of Carbohydrate Antigens with the Immune System in Health and Disease"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Lipoglycosides: Synthesis and New Antimicrobial Mechanism of Action"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Parasitic Glycosylphosphatidylinositols as Tools for Biomedical Research"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Chemical Methods for Engineering Complexity of the Cellular Glycocalyx"
11:20 am - 11:30 am
Discussion
11:30 am - 11:55 am
"Adding a Spectroscopic Dimension to Mass Spectrometry: Fundamental Aspects of Carbohydrate Structure and Application to De Novo Sequencing"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Synthetic Carbohydrate Receptors with Potent Antiviral Activity "
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
2:00 pm - 4:00 pm
Poster Session
4:00 pm - 6:00 pm
Carbohydrates in Host-Microbe Interactions
4:00 pm - 4:25 pm
"Examining and Exploiting Microbial Glycans"
4:25 pm - 4:35 pm
Discussion
4:35 pm - 5:00 pm
"Role of Glycosylation in Orchestrating Host Defense Against the Pathogenesis of Helicobacter pylori "
5:00 pm - 5:10 pm
Discussion
5:10 pm - 5:20 pm
"Synthesis of an Fc Domain-Enhanced Liposomal Cancer Vaccine and Bacterial Vaccine Components"
5:20 pm - 5:25 pm
Discussion
5:25 pm - 5:50 pm
"The Structure and Function of High Affinity Glycan-Glycan Interactions in Infectious Disease"
5:50 pm - 6:00 pm
Discussion
6:00 pm - 7:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure