| Sunday |
| 2:00 - 11:00 pm | Arrival & Registration |
| 5:00 pm | Reception |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Catecholamine
Development, Genes and Stem Cells |
| Session Chair: Kwang-Soo Kim, Harvard University
|
| Elaine Lewis, Oregon Health Sciences Center
Regulated Expression of Norepinephrine Biosynthetic Genes |
| J.F. Brunet, Marseilles
The Transcription Factor Phox2b, Master Gene of the Noradrenergic
Phenotype and of The Visceral Reflex Circuits |
| Ronald McKay, National Institute of Health
Deriving Functional Dopaminergic Midbrain Neurons from ES cells |
| Poster Previews (Group I) |
| Pub and Posters (Group I) |
| Monday |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Conference Photo |
| 9:00 am - 12:30 pm | Catecholamine
Inactivation, Transport, and Consequences |
| Session Chair: Randy D. Blakely, Vanderbilt University
|
| David Sulser, Columbia University
The Mechanism of Neuromelanin Biosynthesis and Its Surprising
Relationship with Synaptic Vesicle Function |
| Ulrik Gether, University of Copenhagen
Activating and Inactivating Zinc Switches in the Dopamine Transporter |
| 10:00 am | Coffee Break |
| Roxanne Vaughan, University of South Dakota
Regulation & Properties of Dopamine Transporter Phosphorylation |
| Marc Caron, Duke University
Regulation of Monoamine Transporter Activity, Trafficking and Targeting |
| Pat Levitt, University of Pittsburgh
Developmental Adaptation Following Prenatal Cocaine Exposure: Are There
Any Rules? |
| Poster Previews (Group I) |
| 12:30 pm - 1:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free of All Formal Activity |
| 4:30 pm - 6:00 pm | Poster Sessions (Group I) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Catecholamine Receptors I: Structure/Function/Diversity |
| Session Chair: Jonathan Javitch, Columbia University |
| Jonathan Javitch, Columbia University
Modeling Beta Adrenergic Receptor Ligand Interactions on the Solved
Structure of Rhodopsin for Drug Development |
| Emiliana Borrelli, IGBMC, Strasbourg
Pre- and Post-Synaptic Functions of the Dopamine D2 Receptors: All is
in the Loop |
| Theresa Branchek, Synaptic Pharmaceutical Corporation
G-protein Coupled Receptors for Trace Amines |
| Poster Previews (Group I) |
| Pub and Posters (Group I) |
| Tuesday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Receptors II: Multimers/Regulation/Interactions |
| Session Chair - Michel Bouvier, University of Montreal |
| Susan George, University of Toronto
Homo- and hetero-Oligomerization of G-Protein Coupled Receptors: Roles
in Receptor Trafficking and Signal Transduction |
| Lakshmi Devi, New York University
Opioid-Adrenergic Interactions: A Role for Oligomerization in Signaling
and Trafficking |
| 10:00 am | Coffee Break |
| Susan Steinberg, Columbia University
Targeting to Caveolae as a Mechanism to Regulate cAMP Accumulation by
Beta Adrenergic Receptors |
| Mark von Zastrow, UCSF
Mechanisms that Control Sorting of GPCRs in the Endocytic Pathway |
| Nancy Zahniser, UCHS
Dopamine/Adenosine Interactions in the Brain |
| Poster Preview: Group II |
| 12:30 pm - 1:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free of All Formal Activity |
| 4:30 pm - 6:00 pm | Poster Sessions (Group I) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Catecholamine Model Systems: From Genetics to Transgenics |
| Session Chair: Jay Hirsch, University of Virginia
|
| Randy Blakely, Vanderbilt University
DA Neuron Toxicity in C. elegans |
| Jay Hirsch, University of Virginia
Bugs on Drugs: Expected and Novel Pathways Regulating Cocaine
Sensitization in Drosophila |
| Richard Palmiter, University of Washington
Dopamine and the Motivation to Eat |
| Poster Previews (Group II) |
| Pub and Posters (Group II) |
| Wednesday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Catecholamine Neuronal and Systems Plasticity |
| Session Chair: Gary Aston-Jones, University of Pennsylvania
|
| Doug Bayliss, University of Virginia
Convergent Modulation of Two-Pore Domain Leak K+ Channels by
Anesthetics and Transmitters Regulates Excitability in Noradrenergic
Neurons and Their Targets |
| Gary Aston-Jones, University of Pennsylvania
Norepinephrine in the bed nucleus of the stria terminalis and opiate
withdrawal: A novel role for the A2 noradrenergic system in affective responses |
| 10:00 am | Coffee Break |
| Ethan Cohen, Harvard University
A New Role for Dopamine in the Dark Adapted Retina |
| Robert Malenka, UCSF
Behavioral Sensitization and Synaptic Plasticity in the Mesolimbic
Dopamine System |
| Julie Kauer, Brown University
Synaptic plasticity in the VTA: Modulation by Amphetamine |
| Poster Previews (Group II) |
| 12:30 pm - 1:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free of All Formal Activity |
| 4:30 pm - 6:00 pm | Poster Sessions (Group II) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Psychostimulant
Modulation of Gene/Protein Expression |
| Session Chair: Terry E. Robinson, University of Michigan
|
| Chip Gerfen, National Institute of Health
Dopamine Receptor Mediated Gene Regulation in the Striatum |
| Terry Robinson, University of Michigan
Drug-Environment Interactions Determine Patterns of
Psychostimulant-Induced Immediate Early Gene Expression in the Striatum |
| Peter Kalivas, Medical University of South Carolina
The Transition to Addiction: A Collaboration Between Catecholamine
Pharmacology and Learning |
| Poster Previews (Group II) |
| Pub an Posters (Group II) |
| Thursday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Catecholamine Disorders and Models |
| Session Chair: Ariel Deutch, Vanderbilt University |
| Mel Feany, Harvard University
Dopaminergic Neurodegeneration in a Drosophila Model of Parkinson's Disease |
| Tim Greenamyre, Emory University
A New Model of Parkinson's Disease: Rotenone, Oxidative Damage and the
Creature from the Black Lagoon |
| 10:00 am | Coffee Break |
| David Robertson, Vanderbilt University
Genetic Deficiencies in NE Synthesis and Reuptake in Autonomic Disorders |
| James Kennedy, Toronto
Dopamine System Genes in Schizophrenia and Tardive Dyskinesia |
| Mark Laruelle, Columbia University
Dopamine in the History of the Schizophrenic Brain: Contributions from
Recent Imaging Studies |
| Louis J. DeFelice, Vanderbilt University: Workshop Preview |
| 12:30 pm - 1:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free of All Formal Activity |
| 4:30 pm - 5:30 pm | Special Professional Workshop: Louis J. DeFelice, Director, Vanderbilt Bridges Program for Minority Education |
| Topic: Minority Student Recruitment and Retention. Working to Increase Diversity in the Next Generation of Catecholamine Researchers |
| 5:30 - 6:00 | Business meeting |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Keynote Presentation |
| Patricia Goldman-Rakic, Yale University
Cortical Dopamine Modulation: Cells, Circuits and Cerebration |
| Pub and Posters (Group II) |
| Friday |
| 7:30 - 8:30 am | Breakfast |
