| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Data Blitz |
| This session will consist of 1.5 min presentations ("big picture/bottom line"; 1 transparency maximum for overhead) by participants giving posters. |
| MONDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Neurotransmission: Receptors, Transporters & Regulation |
| Chair: Rebecca Seal, UCSF, San Francisco |
| Randy Blakely, Vanderbilt, Nashville
"NE transporters: control of surface trafficking and intrinsic activity" |
| Jonathan Javitch, Columbia, New York
"Modeling CA receptor-ligand interactions" |
| Ulrik Gether, U. Copenhagan, Denmark
"DA transporter trafficking: role of PDZ domain interactions and phosphorylation" |
| Louis De Felice, Vanderbilt, Nashville
"Fluorescent imaging of binding and transport in CA transporters" |
| Jay Justice, Jr., Emory, Atlanta
"Cocaine and the DA transporter" |
| 12:45 pm | Lunch / Group Photo |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Sex, Hormones and Catecholamines |
| Chair: Donita Robinson, U. North Carolina, Chapel Hill |
| Jill Becker, U. Michigan, Ann Arbor
"Sex, drugs and dopamine" |
| Anne Etgan, Albert Einstein, New York
"Ovarian steroid regulation of NE neurotransmission" |
| Art Arnold, UCLA, Los Angeles
"Development of DA systems: sex differences and regulation by sex chromosome genes" |
| 9:30 pm - 11:00 pm | Pub and Poster Session I |
| TUESDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Systems and Signaling |
| Chair: Stephanie Cragg, University of Oxford, Oxford |
| Susan Sesack, U. Pittsburgh, Pittsburgh
"The organization of CA systems" |
| Mark Wightman, U. North Carolina, Chapel Hill
"Dynamics of DA neurotransmission" |
| Francois Gonon, CNRS, Bordeaux
"Regulation of DA neurotransmission" |
| James Surmeier, Northwestern, Chicago
"Catecholamines and cell signaling" |
| David Sulzer, Columbia, New York
"Regulation of individual cortical terminals by synaptic dopamine" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Catecholamine/Glutamate Interactions |
| Chair: Margaret Rice, NYU, New York |
| Bita Moghaddam, Yale, New Haven
"Cortical regulation of DA in the accumbens and amygdala" |
| Marina Wolf, Chicago Medical School, North Chicago
"Dopamine receptor regulation of AMPA receptor phosphorylation and trafficking" |
| Robert Edwards, UCSF, San Francisco
"Glutamate release by monoamine neurons" |
| 9:30 pm - 11:00 pm | Pub and Poster Session II |
| WEDNESDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Catecholamines: Plasticity, Learning and Reward |
| Chair: Regina Carelli, UNC, Chapel Hill |
| Anthony Grace, U. Pittsburgh, Pittsburgh
"DA, the amygdala and affective learning" |
| Antonello Bonci, Gallo/UCSF, San Francisco
"Synaptic plasticity in the mesolimbic DA system: implications for addiction" |
| Steve Thomas, U. Pennsylvania, Philadelphia
"NE and memory recall" |
| Patricio O'Donnell, Albany Medical College, Albany
"D1-NMDA interactions and persistent activity in the mature prefrontal cortex" |
| Margaret Gnegy, University of Michigan, Ann Arbor
"Neuroadaptations elicited by repeated, intermittent amphetamine in cultured cells" |
| 12:30 pm | Lunch |
| 1:30 pm - 6:00 pm | Free Time |
| 6:00 pm | Dinner |
| 7:30 pm - 9:00 pm | Catecholamines, Psychopathology and Addiction |
| Chair: Mark Thomas, University of Minnesota, Minneapolis |
| Martin Sarter, Ohio State, Columbus
"Dopaminergic regulation of cortical cholinergic transmission, attentional processes and schizophrenia" |
| Saleem Nicola, Gallo/UCSF, San Francisco
"Dopamine-dependence of nucleus accumbens neuronal firing during goal-directed behavior" |
| Barry Everitt, U. Cambridge
"Aberrant learning and addictive behaviour" |
| THURSDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Catecholamines: Damage and Adaptation |
| Chair: Aldo Badiani, University of Rome, Rome |
| Tim Schallert, U. Texas, Austin
"Degeneration and protection of dopamine neurons: the essential role of motor experience" |
| Michael Zigmond, U. Pittsburgh, Pittsburgh
"Plasticity in DA systems" |
| Marie-Francoise Chesselet, UCLA, Los Angeles
"Phenotypical characterization of new mammalian models of Parkinson's disease" |
| Luigi Zecca, CNR, Milan
"Neuromelanin, aging and Parkinson's Disease" |
| Irwin J. Kopin Travel Award Presentations:
Paul Phillips, UNC, Chapel Hill
"Short-term adaptations of dopamine release in awake rats" |
| Kristin Anstrom, Wake Forest, Winston-Salem
"The effect of restraint stress on VTA sensory gating responses in the
awake, behaving rat" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Workshop: "Ethical Issues in Science" |
| Organizer: Michael Zigmond |
| The specific issues for discussion will depend on the composition and interests of the participants, but could involve problems regarding mentoring relations, authorship, sharing of reagents, conflict of interest and confidentiality. The Workshop will involve initial training sessions for small group leaders (arranged over lunch on days prior to the Workshop). The Workshop will involve small groups dealing with specific cases and then a general discussion involving reports from the breakout groups. Scripts and readings for discussion leaders will be provided by Dr. Zigmond. |
| 6:00 pm | Dinner |
| 7:30 pm - 9:00 pm | Keynote Address |
| Chair: Terry Robinson |
| Speaker: Trevor Robbins, Cambridge University
"Catecholamines: function and dysfunction" |
| FRIDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
