| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PRESENTATIONS FROM EARLY CAREER INVESTIGATORS |
| Discussion Leader: Antony F. McDonagh (University of California, San Francisco, USA) |
| 7:30 pm - 8:00 pm | Heidi L. Schubert (University of Utah, USA)
Mechanisms in Early Tetrapyrrole Biosynthesis |
| 8:00 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:40 pm | Robert M. Larkin (Michigan State University, USA)
Plastid Signals Regulate Nuclear Transcription in Plants |
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | Matthew W. Peters (California Institute of Technology, USA)
Engineering cytochromes P450 BM-3 into selective alkane hydroxylases |
| 9:20 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | TETRAPYRROLES IN SIGNAL TRANSDUCTION |
| Discussion Leader: Judith Burstyn (University of Wisconsin, Madison, USA) |
| 9:00 am - 9:40 am | Michael P. Schmitt (FDA, USA)
Iron transport and Heme-Dependent Gene Regulation in the Gram-Positive Pathogen Corynebacterium diphtheriae |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am - 10:30 am | Photo / Coffee Break |
| 10:30 am - 11:10 am | Kazuhiko Igarashi (Hiroshima University, Japan)
Multilayered Regulation of Gene Expression by Bach1 and Heme |
| 11:10 am - 11:30 am | Discussion |
| 11:30 am - 12:10 pm | Marie-Alda Gilles-Gonzalez (Univ. Texas Southwestern Medical Center, USA)
Sensing of Physiological Gases by Heme-Binding PAS-Domain Proteins |
| 12:10 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | HEME PROTEIN ASSEMBLY AND BIOSYNTHESIS |
| Discussion Leader: Sabeeha Merchant (University of California, Los Angeles, USA) |
| 7:30 pm - 8:10 pm | Linda Thöny-Meyer (ETH Zürich, Switzerland)
Cytochrome c Maturation: Following Heme Along Its Route |
| 8:10 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:10 pm | D. Moira Glerum (University of Alberta, Canada)
Resolving a Sticky Problem: Getting Heme A to Cytochrome Oxidase |
| 9:10 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | ENZYMOLOGY AND REGULATION OF TETRAPYRROLE BIOSYNTHESIS |
| Discussion Leader: Gloria Ferreira (University of South Florida, USA) |
| 9:00 am - 9:40 am | Eileen Jaffe (Fox Chase Cancer Center, USA)
Morpheins, the alternate quaternary states of porphobilinogen synthase |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:10 am | John Phillips (University of Utah, USA)
Crystal structure of uroporphyrinogen decarboxylase: A new view of porphyrinogen intermediates in heme biosynthesis |
| 11:10 am - 11:30 am | Discussion |
| 11:30 am - 12:10 pm | Mats Hansson (Lund University, Sweden)
New Aspects of Magnesium Chelatase Revealed by Mutant and Structural Studies |
| 12:10 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | APPLICATIONS OF SYNTHETIC PORPHYRINS FOR MEDICINE AND INDUSTRY |
| Discussion Leader: Kevin M. Smith (Louisiana State University, USA) |
| 7:30 pm - 8:10 pm | M. Graca H. Vicente (Louisiana State University, USA)
Synthesis and Properties of Cell-targeted Water-soluble Tetrapyrroles |
| 8:10 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:10 pm | Alan E. Rowan (University of Nijmegen, Netherlands)
Functional Self-assembling Porphyrin Nanoarchitectures |
| 9:10 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | EMERGING CONCEPTS IN TETRAPYRROLE BIOLOGY |
| Discussion Leader: Samuel I. Beale (Brown University, USA) |
| 9:00 am - 9:40 am | Thomas Hankeln (University of Mainz, Germany)
Neuroglobin and cytoglobin: Fresh blood for the vertebrate globin family |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:10 am | Olaf Schneewind (University of Chicago, USA)
Transport and Utilization of Heme by Staphylococcus aureus |
| 11:10 am - 11:30 am | Discussion |
| 11:30 am - 12:10 pm | Roy A. Gravel (University of Calgary, Canada)
Gene finding in disorders of vitamin B12 metabolism: how bacteria can reveal a human pathway |
| 12:10 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TETRAPYRROLES IN PHOTOSYNTHETIC ORGANISMS |
| Discussion Leader: J. Clark Lagarias (University of California at Davis, USA) |
| 7:30 pm - 8:10 pm | William A. Cramer (Purdue University, USA)
Structure (3.0 Å)-function of the cytochrome b6f complex from the cyanobacterium, M. laminosus. |
| 8:10 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:10 pm | Alison G. Smith (University of Cambridge, UK)
Ferrochelatase and the Production of Haemoproteins in Plant Cells |
| 9:10 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | TETRAPYRROLE METABOLISM IN DISEASE AND MEDICINE |
| Discussion Leader: Ann Smith (University of Missouri, Kansas City, USA) |
| 9:00 am - 9:40 am | Fiorella Altruda (University of Turin, Italy)
Role of hemopexin and haptoglobin in response to heme mediated oxidative stress |
| 9:40 am - 10:00 am | Discussion |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:10 am | Augustine M.K. Choi (University of Pittsburgh School of Medicine, USA)
Regulation and Function of Heme Oxygenase-1 In Cellular Stresses |
| 11:10 am - 11:30 am | Discussion |
| 11:30 am - 12:10 pm | Derek A. Persons (St. Jude Children's Research Hospital, USA)
Hematopoietic Stem Cell-Targeted Gene Therapy of ß-thalassemia and Sickle Cell Disease using γ-Globin Lentiviral Vectors |
| 12:10 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Wine and Cheese Reception |
| 6:00 pm | Dinner |
| 7:30 pm - 8:15 pm | Business Meeting |
| 8:15 pm - 9:30 pm | KEYNOTE ADDRESS |
| Discussion Leader: Mark O'Brian (State University of New York at Buffalo, USA) |
| 8:15 pm - 9:10 pm | Paul R. Ortiz de Montellano (UC San Francisco, USA)
The Good, the Bad, and the Ugly of Biological Heme Modification |
| 9:10 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
