Saturday |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Session: State-of-the-Art Therapies for Skin Diseases |
| Discussion Leader: Scott Atwood (University of California, Irvine, USA) |
3:45 pm - 4:25 pm | Dennis Roop (University of Colorado, Anschutz Medical Campus, USA) "Stem Cell Therapies for Inherited Skin Diseases" |
4:25 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Development and Evolution of Skin and Its Niche; (Epi)Genetic Regulation of Skin Development and Homeostasis |
| Discussion Leaders: Panteleimon Rompolas (Yale School of Medicine, USA) and Valentina Greco (Yale University, USA) |
7:30 pm - 7:45 pm | Panteleimon Rompolas (Yale School of Medicine, USA) "Novel Insights in the Mechanisms of Epidermal Maintenance by In Vivo Imaging" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:05 pm | Aaron Mertz (Rockefeller University, USA) "Physical and Molecular Crosstalk Underlying Epithelial Stratification In Vivo" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:25 pm | Kynan Lawlor (Peter MacCallum Cancer Centre, Australia) "Investigating a Dermal Niche to Promote Human Interfollicular Epidermal Self-Renewal" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Xiaomin Bao (Stanford University, USA) "Activation of Epidermal Differentiation via Mutual Reinforcement by the p63 Master Transcription Factor and the BAF Chromatin Remodeling Complex" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Carolina Perdigoto (Icahn School of Medicine at Mount Sinai, USA) "Embryonic Maturation of Epidermal Merkel Cells Is Controlled by a Redundant Transcription Factor Network" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Brian Zarnegar (Stanford University, USA) "FastIR Discovery of Epidermal RNA Regulons" |
9:25 pm - 9:30 pm | Discussion |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Signaling Cascades in Epithelia; Epithelial Dysfunction and Advanced Therapeutics |
| Discussion Leaders: Carolina Perdigoto (Icahn School of Medicine at Mount Sinai, USA) and Dennis Roop (University of Colorado, Anschutz Medical Campus, USA) |
9:00 am - 9:15 am | Elyse van Spyk (University of California, Irvine, USA) "Time-Restricted Feeding Uncouples the Circadian Clock and the Cell Cycle of Epidermal Stem Cells, and Alters the Sensitivity to UVB-Induced DNA Damage" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:35 am | Ting Chen (National Institute of Biological Sciences, China) "Origin of Hair Follicle Stem Cells and Bulge Niche" |
9:35 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Susanne Vorhagen (Cologne Graduate School of Ageing Research, Germany) "aPKCl Determines Epidermal Cell Fate Independent of Mitotic Spindle Orientation: Is Lgl the Link?" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Sivan Harel (Columbia University, USA) "Inhibition of JAK-STAT Signaling Promotes Hair Growth" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Julia Frede (University of Cambridge, United Kingdom) "Cell Dynamics in Esophageal Squamous Carcinogenesis" |
10:35 am - 10:40 am | Discussion |
10:40 am - 10:55 am | JeeEun Choi (Harvard Medical School, USA) "The Role of Sirt6 and
Metabolic Reprogramming in Skin Tumorigenesis" |
10:55 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship Component: Advice from Our Leaders |
| Discussion Leader: Yanne Doucet (Columbia University, USA) |
1:30 pm - 2:15 pm | Valentina Greco (Yale University, USA) "Mentoring as a Business Model" |
2:15 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |