Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: The Future of Hair Follicle Regeneration
Discussion Leader: Etienne Wang (Skin Research Institute of Singapore (SRIS), Singapore)
3:45 pm - 4:20 pm
George Cotsarelis (Penn Medicine, USA)
"Discovering the Hair Follicle Stem Cell and Its Role in Hair Loss and Skin Regeneration"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Development of Skin and Other Specialized Epithelial Structures / Diverse Methods of Epidermal Stem-Cell Regulation
Discussion Leaders: Lauren Albrecht (University of California, Los Angeles, USA), Katie Cockburn (Yale School of Medicine, USA), Swarnabh Bhattacharya (Technion - Israel Institute of Technology, Israel) and Yejing Ge (University of Texas MD Anderson Cancer Center, USA)
7:30 pm - 7:45 pm
Venkata Thulabandu (Case Western Reserve University, USA)
"Cell and Non-Cell Autonomous Roles of Ezh2 in Skin Development"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Stephanie Ellis (The Rockefeller University, USA)
"How Cell Competition Shapes Epidermal Development"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Carmit Bar (Icahn School of Medicine at Mount Sinai, USA)
"Polycomb Repressive Complex 1 Controls Patterning of Lingual Papillae by Repressing Sonic Hedgehog Expression"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Wenxiu Ning (Duke University, USA)
"Mechanical Regulation of Stem Cell Fates by Their Differentiated Daughters"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Ritsuko Morita (RIKEN Center for Biosystems Dynamics Research (BDR), Japan)
"The Origin and Induction Processes of Hair Follicle Stem Cells"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Jessica Moore (Yale University, USA)
"Investigating the Role of Ca2+ in Regulating Epidermal Stem Cell Behaviors via Live Imaging"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Approaches to Cancer Biology, Diagnosis and Treatment / Skin Immunology, Regeneration and Healing
Discussion Leaders: Kenneth Lay (A*STAR, Singapore), Cory Simpson (University of Pennsylvania, USA), Yuxuan Miao (Rockefeller University, USA) and Maria Alcolea (University of Cambridge, United Kingdom)
9:00 am - 9:15 am
Richard Clayton (University of Manchester, United Kingdom)
"Neuro-Regulation of Sebaceous Gland Homeostasis"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Aayushi Uberoi (University of Pennsylvania, USA)
"Epithelial-Microbial Crosstalk Modifies Wound Healing Outcomes: From Shotgun Metagenomics to Mechanistic Understanding"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Sarina Harshuk-Shabso (Bar Ilan University, Israel)
"Fgf and Wnt Signaling Pathways Intersect in the Mesenchymal Niche of the Hair Follicle to Regulate the Hair Cycle Clock"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Waseem Nasser (Technion - Israel Institute of Technology, Israel)
"Pathophysiology and Rescue of Stem Cell Failure: A Lesson from the Cornea"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Catherine Yao (Stanford University, USA)
"Dynamic Chromatin Plasticity Drives Intrinsic Resistance to Hedgehog Inhibitors in Basal Cell Carcinoma"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Lindsey Seldin (Vanderbilt University, USA)
"Induction of Epithelial Lineage Infidelity and Hyperplasia by DNA Damage"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Setting Long-Term Goals for Our Careers, Our Institutions and Our Field
Discussion Leader: Guiomar Solanas (Institute for Research in Biomedicine (IRB Barcelona), Spain)
1:30 pm - 2:10 pm
Panel Discussion
Perspectives from Junior and Senior Faculty
Maria Alcolea (University of Cambridge, United Kingdom)
Yejing Ge (University of Texas MD Anderson Cancer Center, USA)
Elizabeth Grice (University of Pennsylvania, USA)
Anthony Oro (Stanford University, USA)
2:10 pm - 2:30 pm
General Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes