Sunday evening, July 29, 8:00 pm
KEYNOTE LECTURE
- Opening/Welcoming Remarks - Tanya Mazur (GRC Site Manager), Steve Heinemann (Chair), and Darrell Brann (Vice Chair)
- Charles Stevens, Salk Institute - "Transmission at excitatory synapses"
Monday morning, June 30, 8:30 am - 12:00 noon
EAA RECEPTORS: Topology & Regulation
- Mary Kennedy, California Institute of Technology, Discussion Leader
- Peter Seeburg, University of Heidelberg - "Mice with genetically altered excitatory neurotransmission"
- Michael Hollmann, Max Planck Inst. - "The significance of N-glycosylation for ionotropic glutamate receptor function"
- Photograph and Coffee Break
- Yael Stern-Bach, Hebrew University - "Pharmacological studies on AMPA and kainate glutamate receptors"
- Mark Mayer, NIH - "Modulation of AMPA Receptors by PEPA:
complex physiology of a novel allosteric ligand"
Monday evening, June 30, 7:30 pm - 9:00 pm
EAA RECEPTORS AND POSTTRANSCRIPTIONAL MODIFICATION
- Susan Amara, Oregon Health Sciences University, Discussion Leader
- Gary Westbrook, Oregon Health Sciences University - "Desensitization of recombinant NMDA receptors: how does it compare to native receptors or does it?"
- Richard Huganir, Johns Hopkins University - "Regulation of Glutamate Receptor Function by Protein-Protein Interactions"
Tuesday morning, July 1, 8:30 am - 12:00 noon
EAA RECEPTORS AND SYNAPTIC ORGANIZATION / PLASTICITY
- Amy MacDermott, Columbia University, Discussion Leader
- Mary Kennedy , California Institute of Technology - "Molecular architecture of the glutamatergic postsynaptic membrane."
- Morgan Sheng , Harvard University - "Molecular organization of glutamatergic synapses"
- Coffee Break
- Craig Jahr , Oregon Health Sciences University - "Glutamate transporters rapidly buffer synaptically released glutamate"
- Robert Malenka, UCSF - "Silent synapses in hippocampus and cortex"
Tuesday evening, July 1, 7:30 pm - 9:00 pm
EAAs, LTD AND LTP
- Holis Cline, Cold Spring Harbor, Discussion Leader
- Mark Bear, Brown University - "Bidirectional synaptic plasticity and its regulation in the cerebral cortex"
- Robert Malinow, Cold Spring Harbor - "Silent synapses and plasticity"
- Poster Session 1
Wednesday morning, July 2, 8:30 am - 12:00 noon
EAAs AND SYNAPTIC PLASTICITY
- Robert Malinow, Cold Spring Harbor, Discussion Leader
- Vadim Bolshakov - "Quantal analysis of a late phase of LTP at unitary CA3-CA1 synapses"
- Amy MacDermott, Columbia University - "The painful truth about Calcium permeable AMPA receptors"
- Coffee Break
- Susunu Tonegawa, MIT - "Memory Mechanism"
- Holis Cline, Cold Spring Harbor - "In vivo observations of neuronal form and function"
Wednesday evening, July 2, 7:30 pm - 9:00 pm
EAA TRANSPORTERS AND CELL DEATH
- Timothy Greenamyre, Emory University, Discussion Leader
- Susan Amara, Oregon Health Sciences University - "Excitatory amino acid transporters: a family in flux"
- Dennis Choi, Washington University - "Why are AMPA receptors important in mediating ischemic brain injury?"
Thursday morning, July 3, 8:30 am - 12:00 noon
METABOTROPIC RECEPTORS / HYPOTHALAMIC FUNCTION
- Steve Heinemann, Discussion Leader
- Roger Nicoll, UCSF - "Glutamate receptors and hippocampal function"
- Jeff Conn, Emory University - "Physiological roles and regulation of metabotropic glutamate receptors in the hippocampus"
- Coffee Break
- Darrell Brann, Medical College of Georgia - "Ionotropic and Metabotropic Glutamate Receptors and Hypothalamic Function"
- Sergio Ojeda, OHSU - "Glial and neuronal metabotropic receptors contribute to the cell-cell signaling mechanism that controls hypothalamic neuropeptide secretion"
- Business Meeting
- Poster Session 2
Thursday evening, July 3, 7:30 pm - 9:00 pm
PATHOPHYSIOLOGICAL IMPLICATIONS OF EAAs
- Dennis Choi, Washington Univ., Discussion Leader
- Jim McNarama, Duke University - "Glutamate Receptor Autoantibodies and Rasmussen's Encephalitis"
- Timothy Greenamyre, Emory University - "Excitotoxic-mitochondrial interactions in neurodegeneration"
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