Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Synaptic, Plasticity and Behavior
7:40 pm - 8:20 pm
"The Ups and Downs of Firing Rate Homeostasis"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Plasticity of Excitatory Transmission in Drug Addiction"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Excitatory Synapses as Key Regulators of Neural Circuits
9:00 am - 9:20 am
"Habenular Neuronal Dynamics Supporting Negative Affective States"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Neural Dynamics and Synaptic Function in Reward Learning and Motivated Behavior"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Cortical Cartography: The Organization of Cell Type-Specific Synaptic Connectivity in The Prefrontal Cortex"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Regulation of Prefrontal Cortex Neuronal Activity by VTA Glutamatergic Afferents"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Dissecting the Neurodevelopmental role of Schizophrenia Gene Variant NRXN1 at Single-Cell Resolution in iPSC-Derived Human Brain Organoid Model"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Insular Cortex to Ventral Striatum Synapses Encode Valence of Social Interaction"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Target-Specific Tuning of Corticothalamic Excitation Through NMDA Receptor Functional Diversity"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Cerebellin-4 in the Prefrontal Cortex Facilitates Remote Recall of Contextual Memories"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Group Photo / Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Excitatory Synapses in Learning and Memory
6:00 pm - 6:20 pm
"Control of Neuronal Excitation-Inhibition Balance by BMP-SMAD1 Signaling"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Active Neuronal Ensembles During Early Brain Development"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Synaptic Integration and Plasticity in Dendrites of Hippocampal Pyramidal Cells During Spatial Learning"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Functional and Behavioral Implication of Presynaptic Facilitation in the Hippocampus"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Experience-Dependent Synaptic Plasticity
9:00 am - 9:20 am
"Input- and Target-Specific Synaptic Plasticity in Neocortical Networks During Sensory Learning"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Mechanisms of Learning and Plasticity in Motor Cortex"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"The Force of Dendritic-Spine Enlargement Facilitating Presynaptic Exocytosis"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"The Effects of Sensory Experience and Oxytocin on Neural Circuit Development and Plasticity"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Diversity and Modulation of Input-Output Transformation in Hippocampal Pyramidal Cells"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Endocannabinoid Signaling in the Dentate Gyrus: A Brake that Controls Synaptic Strength, Spatial Memory and Seizure Activity"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Pathway Convergence and Coordinated Plasticity at Hippocampus : Nucleus Accumbens Synapses"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
New Imaging Tools to Study Synapses
6:00 pm - 6:20 pm
"In Vivo imaging of Excitatory Synaptic Transmission at High Spatiotemporal Resolution"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Mind the gap! Super-Resolution Imaging of the Extracellular Space of Brain Tissue"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Optical Probing of Synaptic G Protein-Coupled Receptors"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"In Vivo Voltage Imaging and Optogenetics Reveal Rules of Dendritic Back-Propagation and Coupling"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Biosensors for Excitatory Synapse Plasticity"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Synaptic Dysfunction in Brain Disorders
9:00 am - 9:20 am
"Stargazin in The Etiology of Neurodevelopmental Disorders"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Synapse Degeneration in Alzheimer's Disease"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Unraveling The Role of mTOR Complexes in Neuronal Function and Disease"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"NMDARs in The Sustained and Brain Region-Specific Actions of Ketamine"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Developmental Changes in Structural Plasticity and Mental Illness"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Investigations of Social Behavior and Nucleus Accumbens Dysfunction in a Shank3 Mouse Model of Autism"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Localized APP Pathology Results in Progressive Network Dysfunction by Disorganizing Spike Timing"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Glutamate Receptors: Structure and Function
6:00 pm - 6:20 pm
"Excitatory Glycine Receptors: New Players in The Brain"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"NMDA Receptor Synaptic Retention: From Synaptic Plasticity to Neurodevelopmental and Neurodegenerative Disorders"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"NMDA Receptors As Molecular Targets for Fast-Acting Antidepressants"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"NMDA Receptor Signaling Mechanisms in Structural Plasticity of Dendrite Spines"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Synapse Specification and Transsynaptic Signaling
9:00 am - 9:20 am
"Transsynaptic Organization by LAR Family Receptor Tyrosine Phosphatases"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"In Vivo Proximity Proteomics to Uncover New Synaptic Mechanisms"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Cell Adhesion-Mediated Regulation of Synaptic Organelle Distribution Controls Dendritic Spine Maturation"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Making and Breaking Transsynaptic Nanoalignment"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Patterned Activity-driven Molecular Diversification During Neonatal Cortical Circuit Formation"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Dendritic Translation in Learning and Memory"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Extracellular Vesicles as Mediators of Trans-Synaptic Signaling and Circuit Connectivity"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Multilayered Control for Subcellular Distribution and functional properties of KaiR1D Autoreceptor"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Gene Transcription in Neural Circuit Function
6:00 pm - 6:20 pm
"Cell Intrinsic and Extrinsic Controls of Circuit Assembly in The Neocortex"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Neuronal Activity-Dependent DNA Repair in Plasticity and Disease"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Organization of Cell Types Across The Mouse Brain"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Clock Genes and the Transcriptional Control of Homeostatic Plasticity in Mammalian Neocortex"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure