|
| 6:00 - 7:15 p.m. | Dinner |
|
| Discussion leader: William Murray, R. W. Johnson |
| 7:20 - 7:30 p.m. | Greeting by GRC Chair and Staff |
| 7:30 - 8:00 p.m. | John Macor, Bristol-Myers Squibb Pharmaceutical Research Institute
The Discovery of Multiple Heterocyclic Templates Producing Sub-Nanomolar PDE5 Inhibitors |
| 8:00 - 8:10 p.m. | Discussion |
| 8:10 - 8:30 p.m. | Todd Lowary, The Ohio State University
Highly Stereocontrolled Glycosylations via 2,3-Anhydrosugar Derivatives |
| 8:30 - 8:40 p.m. | Discussion |
| 8:40 - 9:30 p.m. | John Vederas, University of Alberta
Heterocyclic Amino Acids as Inhibitors of the Diaminopimelate Pathway to L-Lysine |
| 9:30 - 9:45 p.m. | Discussion |
| 9:45 p.m. - | Welcome Reception and Mixer |
|
| 7:30 - 8:30 a.m. | Breakfast |
|
| Discussion Leader: Cathleen Crudden, University of New Brunswick |
| 8:30 - 9:00 a.m. | Yi-Yin Ku, Abbott Laboratories
Asymmetric Synthesis of A-240610 via Atropisomeric Control of Axial Chirality |
| 9:00 - 9:10 a.m. | Discussion |
| 9:10 - 9:50 a.m. | Tadeusz Molinski, University of California, Davis
Marine-Derived Heterocycles. Nature Drives Discovery |
| 9:50 - 10:00 a.m. | Discussion |
| 10:00 - 10:30 a.m. | Photograph |
| 10:30 - 10:45 a.m. | Break |
|
| Discussion Leader: Mike Groziak, SRI International |
| 10:45 - 11:15 a.m. | Thomas Roper, GlaxoWellcome
Convergent Syntheses of Adenosine A2a Agonists: New Approaches to 2-Alkylaminoadenosines |
| 11:15 - 11:25 a.m. | Discussion |
| 11:25 - 12:15 p.m. | Minoru Isobe, Nagoya University
Synthesis of Marine Toxins |
| 12:15 - 12:30 p.m. | Discussion |
| 12:30 - 1:30 p.m. | Lunch |
| 4:00 - 6:00 p.m. | Poster Session # 1 |
| 6:00 - 7:30 p.m. | Dinner |
|
| Discussion Leader: Todd Lowary, The Ohio State University |
| 7:30 - 8:00 pm | Peter Seeberger,
Massachusetts Institute of Technology
Automated Synthesis of Oligosaccharides and Glycosaminoglycans |
| 8:00 - 8:10 p.m. | Discussion |
| 8:10 - 8:30 p.m. | Kevin Moeller, Washington University in St. Louis
Reversing the Polarity of Enolate Equivalents: Developing an Efficient Route to (+)-Nemorensic Acid |
| 8:30 - 8:40 p.m. | Discussion |
| 8:40 - 9:30 p.m. | Laura Kiessling, University of Wisconsin-Madison
Synthesis of Functional Oligosaccharides and Glycoproteins |
| 9:30 - 9:45 p.m. | Discussion |
|
| 7:30 - 8:30 a.m. | Breakfast |
|
| Discussion Leader: Dirk Trauner, University of California, Berkeley |
| 8:30 - 9:10 a.m. | Hans Reissig, Free University of Berlin
Stereoselective Syntheses of Heterocycles via Metallated Alkoxyallenes |
| 9:10 - 9:20 a.m. | Discussion |
| 9:20 - 10:00 a.m. | Matthew Shair, Harvard University
From Target-Oriented Synthesis to Diversity-Oriented Synthesis and Their Use in Exploring Cell Biology |
| 10:00 - 10:10 a.m. | Discussion |
| 10:10 - 10:40 a.m. | Break, Meeting of Past and Present GRC Heterocycles Chairs |
|
| Discussion Leader: Li Deng, Brandeis University |
| 10:40 - 11:10 a.m. | Franco Cozzi, University of Milan
Poly(ethylene glycol)-supported Synthesis of Heterocycles and Chiral Heterocyclic Ligands and Catalysts |
| 11:10 - 11:20 a.m. | Discussion |
| 11:20 - 12:15 p.m. | Eric Jacobsen, Harvard University
Target-Oriented Synthesis Based on Asymmetric Catalytic Methods |
| 12:15 - 12:30 p.m. | Discussion |
| 12:30 - 1:30 p.m.. | Lunch |
| 4:00 - 6:00 p.m. | Late-Breaking News Session |
| 6:00 - 7:30 p.m. | Dinner |
|
| Discussion Leader: Jeff Johnston, Indiana University |
| 7:30 - 8:00 p.m. | Stéphane Caron, Pfizer
Process Research Towards the Enantioselective Synthesis of a NK1 Receptor Antagonist |
| 8:00 - 8:10 p.m. | Discussion |
| 8:10 - 8:30 p.m. | Robert Grossman, University of Kentucky
[5 + 1] Annulation Route to Highly Substituted and Functionalized Piperidines: A Heterocycle-Forming Double Michael Reaction |
| 8:30 - 8:40 p.m. | Discussion |
| 8:40 - 9:30 p.m. | Viresh Rawal, University of Chicago
New Methods and Strategies for the Stereocontrolled Asymmetric Synthesis of Indole Alkaloids |
| 9:30 - 9:45 p.m. | Discussion |
|
| 7:30 - 8:30 a.m. | Breakfast |
|
| Discussion Leader: Bob Grossman, University of Kentucky |
| 8:30 - 9:10 a.m | James Leighton, Columbia University
Strained Silacycles in Organic Synthesis |
| 9:10 - 9:20 a.m. | Discussion |
| 9:20 - 10:00 a.m. | Gunda Georg, University of Kansas
Synthesis and Evaluation of Novel Heterocyclic Anticancer Agents |
| 10:00 - 10:10 a.m. | Discussion |
| 10:10 - 10:35 a.m. | Break |
| 10:35 - 10:40 a.m. | Nominations for Chair for 2003 |
|
| Discussion Leader: Scott Nelson, University of Pittsburgh |
| 10:40 - 11:10 a.m. | Tony Zhang, Eli Lilly
Selective Synthesis of Heterocycles for the Process Development of 5HT1a Antagonists |
| 11:10 - 11:20 a.m. | Discussion |
| 11:20 - 12:15 p.m. | Greg Fu, Massachusetts Institute of Technology
Asymmetric Catalysis with "Planar-Chiral" Heterocycles |
| 12:15 - 12:30 p.m. | Discussion |
| 12:30 - 1:30 p.m. | Lunch |
| 4:00 - 6:00 p.m. | Poster Session # 2 |
| 6:00 - 7:30 p.m. | Dinner |
|
| Discussion Leader: Brian Stoltz, California Institute of Technology |
| 7:30 - 8:00 p.m. | James McNamara, Merck
Asymmetric Syntheses of an NK-1 Receptor Antagonist |
| 8:00 - 8:10 p.m. | Discussion |
| 8:10 - 8:30 p.m. | Justin Du Bois, Stanford University
Catalytic Insertion Reactions for the Amination of C-H Bonds |
| 8:30 - 8:40 p.m. | Discussion |
| 8:40 - 9:30 p.m. | Alan Armstrong, Imperial College
Asymmetric Heteroatom Transfer from Small-Ring Heterocycles |
| 9:30 - 9:45 p.m. | Discussion |
|
| 7:30 - 8:30 a.m. | Breakfast |
|
| Discussion Leader: Elke Schoffers, Western Michigan University |
| 8:30 - 9:10 a.m. | Eric Block, State University of New York, Albany
Adventures in 1,2-Dichalcogenin Chemistry |
| 9:10 - 9:20 a.m. | Discussion |
| 9:20 - 10:00 a.m. | Bernhard Kräutler, University of Innsbruck
Towards Solving the Riddle of Chlorophyll Breakdown |
| 10:00 - 10:10 a.m. | Discussion |
| 10:10 - 10:20 a.m. | Election of Chair |
| 10:20 - 10:40 a.m. | Break |
|
| Discussion Leader: Justin Du Bois, Stanford University |
| 10:40 - 11:10 a.m. | Kay Brummond, West Virginia University
FR901483: A Tandem Cationic Aza-Cope-Mannich Cyclization Approach |
| 11:10 - 11:20 a.m. | Discussion |
| 11:20 - 12:15 p.m. | Larry Overman, University of California, Irvine
Recent Studies in Alkaloid Total Synthesis |
| 12:15 - 12:30 p.m. | Discussion |
| 12:30 - 1:30 p.m. | Lunch |
| 4:00 - 6:00 p.m. | Chairman's Reception & Wine Tasting |
| 6:00 - 7:30 p.m. | Banquet |
|
| Discussion Leader: Erik Sorensen, The Scripps Research Institute |
| 7:30 - 8:00 p.m. | Ray C. F. Jones, Loughborough University
Ringing the Changes: Expected and Unexpected Annulations of Imidazolines |
| 8:00 - 8:10 p.m. | Discussion |
| 8:10 - 9:10 p.m. | Albert Eschenmoser, ETH-Zürich/Scripps
Chemical Etiology of Nucleic Acid Structure: Strategy and Recent Results |
| 9:10 - 9:25 p.m. | Discussion |
| 9:25 - 9:40 p.m. | William Murray: Vice Chair's Remarks |
|
| 7:30 - 8:30 a.m. | Breakfast |
| 9:00 a.m. | Bus Departs for Logan Airport, Boston |
