The GRC on Heterocyclic Compounds is one of the longest running Gordon Research Conferences. Its longevity reflects the vitality and importance of the subject. The field of heterocyclic organic chemistry provides the chemical reactions and strategies that enable the preparation of new pharmaceutical agents, molecular probes, structurally complex, heterocycle-containing natural products, and organic materials. The continued development of this branch of chemistry is vital to the goal of achieving efficient, cost-effective solutions to increasingly complex problems in organic synthesis, as they are encountered in industrial and college/university research laboratories. Through formal research lectures from outstanding scientists concerned with the field of heterocyclic organic chemistry, poster presentations, and informal chemical discussions, this conference provides an excellent opportunity to any scientist who is seeking knowledge of the most recent advances in this field. The scientific program for this meeting is impressive. I encourage all who are interested to apply to this meeting.