Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Inhibitory Synapses and Circuits |
| Discussion Leader: Jean-Marc Fritschy (University of Zurich, Switzerland) |
7:40 pm - 8:20 pm | Zoltan Nusser (Institute of Experimental Medicine, Hungary) "Functional Consequences of Synaptic GABAA Receptor Diversity" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Hannah Monyer (Heidelberg University Hospital / German Cancer Research Center (DKFZ), Germany) "Inhibition in the Brain: From Individual Neurons to Complex Systems Effects" |
9:15 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Mechanisms of Inhibitory Synaptic Function |
| Discussion Leader: Istvan Mody (David Geffen School of Medicine, University of California, Los Angeles, USA) |
9:00 am - 9:25 am | Cheng-Chang Lien (National Yang-Ming University, Taiwan) "Pathway-Specific Recruitment of Dentate Gyrus Interneurons" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Afia Ali (University College London School of Pharmacy, United Kingdom) "The Mechanisms of Hippocampal CCK Interneuron Circuits in Health and in an Epileptic Model" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Pablo Castillo (Albert Einstein College of Medicine, USA) "Presynaptic Protein Synthesis in Inhibitory LTD" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Larry Trussell (Oregon Health Sciences University, USA) "Effective Convergence of Interneurons and Short-Term Plasticity" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Natalia De Marco Garcia (Weill Cornell Medical Institute, USA) "Sensory Inputs Control the Integration of Neurogliaform Interneurons into Cortical Circuits" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Evan Vickers (Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland) "Bidirectional Spike-Timing Dependent Plasticity of Parvalbumin Interneuron Output Synapses in Auditory Cortex" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Plasticity of Inhibitory Circuits |
| Discussion Leader: Chris McBain (National Institutes of Health, USA) |
7:30 pm - 8:00 pm | Arianna Maffei (Stony Brook University, State University of New York, USA) "Inhibitory Synaptic Plasticity in Developing Cortical Circuits" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Daniel Feldman (University of California, Berkeley, USA) "Rapid Homeostasis by Inhibitory Circuit Plasticity in Somatosensory Cortex" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Marlene Bartos (University of Freiburg, Germany) "Joint AMPA and Group I mGlu Receptor Activation Is Required for Synaptic Plasticity in Dentate Gyrus Fast-Spiking Interneurons" |
9:20 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | GABA and Interneurons in Developing Circuits |
| Discussion Leader: Hongjun Song (Johns Hopkins University, USA) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:30 am | Helen Scharfman (Nathan Kline Institute / New York University, USA) "Diverse Roles of Dentate Gyrus Neurogenesis" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:05 am | Alejandro Schinder (Leloir Institute, Argentina) "Information Processing by Adult-Born Granule Cells Defined by Distinctive Coupling to Feedback and Feedforward Networks" |
10:05 am - 10:15 am | Discussion |
10:15 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Juan Song (University of North Carolina at Chapel Hill, USA) "Interplay Between Interneuron Circuitry and Mental Disorder Risk Factor DISC1 Regulates Excitatory Synapse Development" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Josef Bischofberger (University of Basel, Switzerland) "Bidirectional GABAergic Control of AP Firing in Newly Generated Young Hippocampal Granule Cells" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:20 pm | Laszlo Vutkits (University of Geneva, Switzerland) "General Anesthesia and the Modulation of Synaptic Plasticity in the Developing Brain" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Interneuron Development and Diversity |
| Discussion Leader: Carolyn Houser (David Geffen School of Medicine, University of California, Los Angeles, USA) |
7:30 pm - 8:00 pm | Christian Mayer (New York University Langone Medical Center, USA) "The Contribution of Lineage to Forebrain Inhibitory Circuitry" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Beatriz Rico (King's College London, United Kingdom) "Differential Contribution of Fast-Spiking Interneurons and CCK Basket Cells to Network Dynamics" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Pico Caroni (Friedrich Miescher Institute, Switzerland) "PV Basket Cell Subpopulations: Distinct Microcircuits and Distinct Roles in Learning" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mechanisms of Inhibitory Synapse Formation |
| Discussion Leader: Jean-Marc Fritschy (University of Zurich, Switzerland) |
9:00 am - 9:25 am | Suzanne Paradis (Brandeis University, USA) "Semaphorin4D Drives the Rapid Assembly of GABAergic Synapses" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Jasmina Jovanovic (University College London, United Kingdom) "Investigating the Structural Role of GABAA Receptors in Synapse Initiation and Functional Maturation" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Guenter Schwarz (University of Cologne, Germany) "Homeostatic Control of Gephyrin Clustering by Palmitoylation and Nitrosylation" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Shiva Tyagarajan (University of Zurich, Switzerland) "The 'Histone Code' of Gephyrin Cluster Regulation" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Sabine Levi (INSERM UMR839, France) "Adenosine Signaling as a Detector and Stabilizer of Newly Formed GABA Synapses" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Corette Wierenga (Utrecht University, The Netherlands) "Sema4D Promotes Stabilization of Nascent Inhibitory Boutons" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | GABA Signaling in Health and Disease |
| Discussion Leader: Marco Capogna (MRC Anatomical Neuropharmacology Unit, United Kingdom) |
7:30 pm - 8:00 pm | Laura Cancedda (Italian Institute of Technology, Italy) "Modulation of Intracellular Chloride to Regulate Synaptic Plasticity and Rescue Cognitive Functions in Down Syndrome" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Jamie Maguire (Tufts University School of Medicine, USA) "Stress-Induced Compromise in GABAergic Inhibition: From Physiology to Pathophysiology" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Bernhard Bettler (University of Basel, Switzerland) "Deconstructing GABAB Receptor Effector Systems" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Inhibition in Intact Circuits |
| Discussion Leader: Ivan Soltesz (Stanford University, USA) |
9:00 am - 9:25 am | Takao Hensch (Harvard University, USA) "Inhibitory Circuits and Critical Periods" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Thomas Klausberger (Medical University of Vienna, Austria) "Interneurons of the Prefrontal Cortex and Working Memory" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Adam Kepecs (Cold Spring Harbor Laboratory, USA) "Mapping the Behavioral Repertoire of Identified Interneurons During Decision Making" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Massimo Scanziani (University of California, San Diego, USA) "Visual Processing by Cortical Inhibitory Neurons" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Sunil Gandhi (University of California, Irvine, USA) "Opening a New Critical Period Using Inhibitory Neuron Transplantation" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Edward Zagha (Yale University School of Medicine, USA) "Neural Circuit Dynamics in Motor Cortex Linking Sensory Input to Goal-Directed Motor Output" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | GABAA Receptors as Therapeutic Targets |
| Discussion Leader: Zoltan Nusser (Institute of Experimental Medicine, Hungary) |
7:30 pm - 8:00 pm | Elif Engin (McLean Hospital / Harvard Medical School, USA) "Intrahippocampal Circuits Regulating Fear and Anxiety: The Role of Alpha2-GABAA Receptors" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Bernhard Luscher (Pennsylvania State University, USA) "Homeostatic Synaptic Control of a Depression-Related Brain State by GABAergic Deficits and Ketamine" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Hanns Ulrich Zeilhofer (University of Zurich, Switzerland) "GABAA Receptors in Spinal Pain Control" |
9:20 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |