| SUNDAY |
| 2:00 pm - 11:00 pm | Arrival and Check-in |
| 4:00 pm - 6:00 pm | Opening Reception |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | EVOLUTION OF MEIOSIS, SEXUAL REPRODUCTION, & CHROMOSOME STRUCTURE |
| Discussion Leader: Scott Hawley (Stowers Institute) |
| 7:40 pm - 7:55 pm | Zac Cande (University of California, Berkeley)
"Diplomixis in the basal eukaryote Giardia: a parasexual precursor to meiosis" |
| 7:55 pm - 8:02 pm | Discussion |
| 8:02 pm - 8:17 pm | Mimi Zolan (Indiana University)
"Parthenogenesis, Meiosis, and Pseudo-meiosis in Daphnia pulex" |
| 8:17 pm - 8:24 pm | Discussion |
| 8:24 pm - 8:39 pm | Harmit Singh Malik (Fred Hutchinson Cancer Research Center)
"Genetic conflict during female meiosis and Drosophila speciation" |
| 8:39 pm - 8:46 pm | Discussion |
| 8:46 pm - 9:01 pm | Jeremy Wang (University of Pennsylvania)
"Regulation of male meiosis by the X chromosome-linked genes in mice" |
| 9:01 pm - 9:08 pm | Discussion |
| 9:08 pm - 9:23 pm | James Turner (MRC National Institute of Medical Research, UK)
"Meiotic Silencing and Gene Content of the Mammalian X Chromosome" |
| 9:23 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | REGULATION AND PERTURBATION OF MEIOTIC ENTRY AND PROGRESSION |
| Discussion Leader: Abby Dernburg (University of California, Berkeley) |
| 9:00 am - 9:15 am | Masayuki Yamamoto (University of Tokyo)
"Molecular basis to remove meiotic mRNAs selectively in mitotic fission yeast cells" |
| 9:15 am - 9:25 am | Discussion |
| 9:25 am - 9:40 am | David Page (HHMI and Whitehead Institute)
"Competence to initiate meiosis: a major transition state in germ cell development" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:05 am | Alex Bortvin (Carnegie Institution of Washington)
"Mouse Maelstrom and transposon silencing at the onset of meiosis" |
| 10:05 am - 10:15 am | Discussion |
| 10:15 am | Coffee Break / Group Photo |
| 10:45 am - 11:00 am | Terry Orr-Weaver (Whitehead Institute and MIT)
"Developmental regulation of the meiotic cell cycle" |
| 11:00 am - 11:10 am | Discussion |
| 11:10 am - 11:25 am | Paul Burgoyne (MRC National Institute of Medical Research, UK)
"MSCI failure, unrepaired DSBs, and mid pachytene spermatocyte apoptosis" |
| 11:25 am - 11:35 am | Discussion |
| 11:35 am - 11:50 am | Angelika Amon (HHMI and MIT)
"Effects of age on meiosis in budding yeast" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:15 pm | Patricia Hunt (Washington State University)
"Environmental effects on recombination in mammals" |
| 12:15 pm - 12:25 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 1 (posters 1-55, odd numbers presenting) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | RECOMBINATION DISTRIBUTIONS: HOT (AND NOT) SPOTS |
| Discussion Leader: Anne Villeneuve (Stanford University) |
| 7:30 pm - 7:45 pm | Gerry Smith (Fred Hutchinson Cancer Research Center)
"Genetic control of the genome-wide distribution of meiotic DSBs and crossovers in S. pombe" |
| 7:45 pm - 7:54 pm | Discussion |
| 7:54 pm - 8:09 pm | Maria Jasin (Memorial Sloan-Kettering Cancer Center)
"Distribution of crossovers and noncrossovers within a mouse hotspot" |
| 8:09 pm - 8:18 pm | Discussion |
| 8:18 pm - 8:33 pm | Philippe Bois (Scripps Research Institute, Florida)
"Regulation of mouse recombination hotspots" |
| 8:33 pm - 8:42 pm | Discussion |
| 8:42 pm - 8:57 pm | Bernard de Massy (Institute of Human Genetics, Montpellier)
"Initiation of meiotic recombination: hidden and moving sites in the genome" |
| 8:57 pm - 9:06 pm | Discussion |
| 9:06 pm - 9:21 pm | Jeff Sekelsky (University of North Carolina, Chapel Hill)
"Crossover distribution in Drosophila on large and small scales" |
| 9:21 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | HOMOLOGOUS PAIRING AND SYNAPSIS |
| Discussion Leader: Doug Bishop (University of Chicago) |
| 9:00 am - 9:15 am | Abby Dernburg (University of California, Berkeley)
"Regulation of homolog pairing and synapsis by cell cycle kinases" |
| 9:15 am - 9:25 am | Discussion |
| 9:25 am - 9:40 am | Monica Colaiacovo (Harvard Medical School)
"Synaptonemal complex formation in C. elegans meiosis" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:05 am | Eva Hoffmann (University of Sussex)
"Regulation and functions of the synaptonemal complex in budding yeast" |
| 10:05 am - 10:15 am | Discussion |
| 10:15 am | Coffee Break |
| 10:45 am - 11:00 am | Akira Shinohara (Osaka University)
"Control of synaptonemal complex formation by SCF ubiquitin ligase complex" |
| 11:00 am - 11:10 am | Discussion |
| 11:10 am - 11:25 am | Denise Zickler (Université Paris-Sud)
"Msh4, Mer3 and Mlh1 in Sordaria: multiple coordinate roles from homologous pairing to chiasma formation" |
| 11:25 am - 11:35 am | Discussion |
| 11:35 am - 11:50 am | Tomas Naranjo (Universidad Complutense, Madrid)
"Do terminal regions of cereal chromosomes contain specific sequences that aid homologue identification?" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:15 pm | Giovanni Bosco (University of Arizona)
"Drosophila condensin II subunit Cap-H2 antagonizes male meiotic chromosome pairing and interacts with the achiasmate pairing maintenance gene teflon" |
| 12:15 pm - 12:25 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 2 (posters 1-55, even numbers presenting) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CHROMOSOME SEGREGATION: SPINDLES, KINETOCHORES & COHESION |
| Discussion Leader: Zac Cande (University of California, Berkeley) |
| 7:30 pm - 7:45 pm | Hiro Ohkura (The University of Edinburgh)
"Post-pachytene chromosome organisation and spindle assembly in Drosophila female meiosis" |
| 7:45 pm - 7:54 pm | Discussion |
| 7:54 pm - 8:09 pm | Kim McKim (Waksman Institute, Rutgers University)
"Analysis of Drosophila meiotic spindles with genetic interactions" |
| 8:09 pm - 8:18 pm | Discussion |
| 8:18 pm - 8:33 pm | Sharon Bickel (Dartmouth College)
"Aging predisposes oocytes to meiotic nondisjunction when the cohesin subunit Smc1 is reduced" |
| 8:33 pm - 8:42 pm | Discussion |
| 8:42 pm - 8:57 pm | Yoshinori Watanabe (University of Tokyo)
"Direct link between heterochromatin and centromeric protector shugoshin" |
| 8:57 pm - 9:06 pm | Discussion |
| 9:06 pm - 9:21 pm | Wolfgang Zachariae (Max Planck Institute of Molecular Cell Biology and Genetics)
"The coordination of recombination and monopolar attachment in meiosis I" |
| 9:21 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | INITIATION OF MEIOTIC RECOMBINATION |
| Discussion Leader: Scott Keeney (Memorial Sloan-Kettering Cancer Center) |
| 9:00 am - 9:15 am | Alain Nicolas (Insitut Curie)
"Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites" |
| 9:15 am - 9:25 am | Discussion |
| 9:25 am - 9:40 am | Kunihiro Ohta (University of Tokyo)
"Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:05 am | Franz Klein (University of Vienna)
"Protein-chromosome interactions during early meiotic recombination" |
| 10:05 am - 10:15 am | Discussion |
| 10:15 am | Coffee Break |
| 10:45 am - 11:00 am | Nancy Kleckner (Harvard University)
"Integration of chromosomal events during DSB formation" |
| 11:00 am - 11:10 am | Discussion |
| 11:10 am - 11:25 am | Mathilde Grelon (INRA, Station de Génétique et d'Amélioration des Plantes)
"Identification of meiotic DSB forming proteins in Arabidopsis thaliana" |
| 11:25 am - 11:35 am | Discussion |
| 11:35 am - 11:50 am | Dan Camerini-Otero (Genetics and Biochemistry Branch, NIDDK, NIH)
"The mouse Spo11, Hop2 and Mnd1 proteins in meiotic recombination" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:15 pm | John Schimenti (Cornell University)
"Novel meiotic recombination functions in mice" |
| 12:15 pm - 12:25 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 3 (posters 56-110, odd numbers presenting) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CHROMOSOME DYNAMICS |
| Discussion Leader: Yoshinori Watanabe (University of Tokyo) |
| 7:30 pm - 7:45 pm | Yasushi Hiraoka (Osaka University)
"Movements of homologous chromosomes in fission yeast meiosis" |
| 7:45 pm - 7:54 pm | Discussion |
| 7:54 pm - 8:09 pm | Mike Dresser (Oklahoma Medical Research Foundation)
"Extremely dynamic chromosome dynamics" |
| 8:09 pm - 8:18 pm | Discussion |
| 8:18 pm - 8:33 pm | Sean Burgess (University of California, Davis)
"Cis and trans effects on homolog interaction in budding yeast" |
| 8:33 pm - 8:42 pm | Discussion |
| 8:42 pm - 8:57 pm | Anne Villeneuve (Stanford University)
"Crossover-triggered differentiation of meiotic bivalents directs chromosome behavior during the meiotic divisions" |
| 8:57 pm - 9:06 pm | Discussion |
| 9:06 pm - 9:21 pm | Scott Hawley (Stowers Institute)
"The fate of heterochromatc pairings: heterochromatic threads connect oscillating achiasmate chromosomes during meiosis" |
| 9:21 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am - 9:00 am | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 9:00 am - 12:30 pm | MECHANISMS OF HOMOLOGOUS RECOMBINATION |
| Discussion Leader: Gerry Smith (Fred Hutchinson Cancer Research Center) |
| 9:00 am - 9:15 am | Doug Bishop (University of Chicago)
"Dmc1 and Recombination Partner Choice" |
| 9:15 am - 9:25 am | Discussion |
| 9:25 am - 9:40 am | Nancy Hollingsworth (SUNY Stonybrook)
"Phosphorylation and regulation of meiotic recombination" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:05 am | Simon Boulton (London Research Institute, Clare Hall Labortories)
"Regulation of meiotic recombination by the anti-recombinase SPAR1" |
| 10:05 am - 10:15 am | Discussion |
| 10:15 am | Coffee Break |
| 10:45 am - 11:00 am | Neil Hunter (University of California, Davis)
"Mechanism and regulation of joint molecule formation" |
| 11:00 am - 11:10 am | Discussion |
| 11:10 am - 11:25 am | Michael Lichten (National Cancer Institute, NIH)
"Regulation of the formation and resolution of recombination intermediates during meiotic progression" |
| 11:25 am - 11:35 am | Discussion |
| 11:35 am - 11:50 am | Paula Cohen (Cornell University)
"Interactions between the MUS81 and MSH4/MSH5 recombination pathways in the mouse" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:15 pm | Rhona Borts (University of Leicester)
"Association of mutations in meiotic recombination genes and male infertility" |
| 12:15 pm - 12:25 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 4 (posters 56-110, even numbers presenting) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CROSSOVER CONTROL |
| Discussion Leader: Kim McKim (Rutgers University) |
| 7:30 pm - 7:45 pm | Jennifer Fung (University of California, San Francisco)
"Global analysis of the meiotic crossover landscape" |
| 7:45 pm - 7:54 pm | Discussion |
| 7:54 pm - 8:09 pm | Chris Franklin (University of Birmingham, UK)
"AtRPA1a an Arabidopsis replication protein A family member is required for Class I meiotic crossover formation, but is dispensable for DNA double-strand break repair" |
| 8:09 pm - 8:18 pm | Discussion |
| 8:18 pm - 8:33 pm | Judith Yanowitz (Carnegie Institution of Washington)
"GAK-1, an autosome-specific factor required for X chromosome recombination" |
| 8:33 pm - 8:42 pm | Discussion |
| 8:42 pm - 8:57 pm | Greg Copenhaver (University of North Carolina, Chapel Hill)
"Forward and Reverse Approaches for Meiotic Analysis Using Arabidopsis Tetrads" |
| 8:57 pm - 9:06 pm | Discussion |
| 9:06 pm - 9:21 pm | Barbara Meyer (HHMI and University of California, Berkeley)
"Control of crossover number and distribution" |
| 9:21 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
