Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Mitochondria in Nitrogen Metabolism
Discussion Leader: Warwick Dunn (University of Liverpool, United Kingdom)
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:50 pm
Craig Thompson (MSKCC, United States)
"The Central Role of Mitochondria in Nitrogen Metabolism"
8:50 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Microbiome and Human Metabolome
Discussion Leader: Elaine Holmes (Murdoch University, Australia)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
Rima Kaddurah-Daouk (Duke University, United States)
"Brain Health at Cross Roads of Gut Microbiome Exposome Genome and Metabolome"
9:30 am - 9:45 am
Discussion
9:45 am - 10:10 am
Sofia Forslund (ECRC (MDC & Charité), Germany)
"Joint Host-Microbiome Investigations into some Immune-Related Health States"
10:10 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Matej Oresic (Örebro University, Sweden)
"Gut Microbiome as Mediator of Chemical Exposome - Host Metabolism Crosstalk"
11:20 am - 11:35 am
Discussion
11:35 am - 12:00 pm
Dirk Haller (Technical University of Munich, Germany)
"Microbiome-Metabolite Interactions and Inflammation"
12:00 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Susan Sumner (University of North Carolina at Chapel Hill, United States) and Warwick Dunn (University of Liverpool, United Kingdom)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Immunometabolism
Discussion Leader: Thomas Hankemeier (Leiden University, The Netherlands)
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:40 pm
Ron Heeren (Maastricht University, The Netherlands)
"Spatial Metabolomics of Health and Disease"
6:40 pm - 6:55 pm
Discussion
6:55 pm - 7:30 pm
David Wishart (University of Alberta, Canada)
"Metabolomics and Immunometabolism- What Can We Learn?"
7:30 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Nutrition and Precision Health
Discussion Leader: Susan Sumner (University of North Carolina at Chapel Hill, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
Elaine Holmes (Murdoch University, Australia)
"Metabolic Phenotyping for Precision Health"
9:30 am - 9:45 am
Discussion
9:45 am - 10:10 am
Soumeya Bekri (Rouen University Hospital, France)
"Cross-Talk between Rare and Common Diseases through Omics Lenses"
10:10 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Wiebke Arlt (MRC London Institute of Medical Sciences (LMS), United Kingdom)
"Steroid Metabolism and Contribution to Health and Disease"
11:20 am - 11:35 am
Discussion
11:35 am - 12:00 pm
Hannelore Daniel (Technical University of Munich, Germany)
"Metabolic Phenotyping for Precision Nutrition"
12:00 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Capturing the Spatial Organization of Metabolism
Discussion Leader: Ron Heeren (Maastricht University, The Netherlands)
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:30 pm
Per Andren (Uppsala University, Sweden)
"Mapping Neurotransmitter Networks in the Brain"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
Ingela Lanekoff (Uppsala University, Sweden)
"Spatial Metabolomics – Picturing Activities in situ "
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:40 pm
Shawn Davidson (Princeton University, United States)
"Spatially-Resolved =Assessment of Metabolism using Iso-Imaging"
7:40 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Multiomics to Assess Disease and Health Status
Discussion Leader: Karsten Suhre (Weill Cornell Medicine-Qatar, Qatar)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:45 am
Liang Liang (University of California San Francisco, United States)
"The Metabolomic Clock of Human Pregnancy"
9:45 am - 10:05 am
Discussion
10:05 am - 10:35 am
Coffee Break
10:35 am - 11:05 am
Jingyuan Fu (University Medical Center Groningen, The Netherlands)
"Tacking the Gut-Liver Axis in Human Metabolome: From Association to Organ-on-a-Chip"
11:05 am - 11:20 am
Discussion
11:20 am - 11:50 am
Thomas Hankemeier (Leiden University, The Netherlands)
"Integrative Multiomics for Health and Disease"
11:50 am - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Biohacking Metabolism for Prolonged Lifespan and Healthspan
Discussion Leader: Rima Kaddurah-Daouk (Duke University, United States)
6:00 pm - 6:25 pm
Johan Auwerx (Ecole Polytechnique Federale de Lausanne, Switzerland)
"Cross-Species Genetic Mapping of New Players in Mitochondria and AgingCross-Species Genetic Mapping of New Players in Mitochondria and Aging"
6:25 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
Norbert Perrimon (Harvard Medical School, United States)
"Metabolic Dysregulation Associated with a Drosophila Cachexia Model"
7:05 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
Eileen White (Rutgers Cancer Institute, United States)
"Role of Autphagy in Metabolism"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Advances in Metabolomics Technologies
Discussion Leader: David Wishart (University of Alberta, Canada)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
Maria Fedorova (Technical University Dresden, Germany)
"Lipidomics Measures of Human Health Status"
9:30 am - 9:45 am
Discussion
9:45 am - 10:10 am
Christian Metallo (The Salk Institute for Biological Studies, United States)
"Quantifying Organelle-Specific Metabolic Processes to Decipher Biochemical Networks Within Cells"
10:10 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Claire O'Donovan (EMBL-EBI, United Kingdom)
"Infrastructures to Support Metabolomics"
11:20 am - 11:35 am
Discussion
11:35 am - 12:00 pm
Yulan Wang (Nanyang Technological University, Singapore)
"Human Metabolome Technologies"
12:00 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Harnessing Metabolic Individuality for Studying Health and Disease
Discussion Leader: Matej Oresic (Örebro University, Sweden)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:40 pm
Karsten Suhre (Weill Cornell Medicine-Qatar, Qatar)
"Connecting the Metabolome, Epigenome and Proteome for a Deeper Understanding of Human Disease"
6:40 pm - 6:55 pm
Discussion
6:55 pm - 7:05 pm
Victoria Pozo (Vrije Universiteit, The Netherlands)
"A Metabolomics Approach to Characterize the Xenobiotic Machinery of Novel Human Hepatic Models"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:20 pm
Wendy Lin (Weill Cornell Medicine, Sloan Kettering Institute, United States)
"Dissecting the Impact of the Gut Microbiome on Colorectal Cancer Metabolism"
7:20 pm - 7:25 pm
Discussion
7:25 pm - 7:35 pm
Laura Corbin (MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom)
"The Metabolomic Signature of Weight Loss in the Diabetes Remission Clinical Trial"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure