| SUNDAY |
| (7:30 pm - 9:30 pm) | GLOBAL REGULATORY NETWORKS, COMPUTATIONAL STUDIES |
| Discussion Leader: Richard Losick (Harvard University) |
| Adam Arkin (University of California, Berkeley)
"Motifs, modules and comparative analysis of B. subtilis signal transduction pathways: sporulation initiation and chemotaxis" |
| Chet Price (University of California, Davis)
"Cause and effect of the general stress response in Bacillus subtilis" |
| Michael Laub (Harvard University)
"Genomic analysis of the regulatory network controlling a bacterial cell cycle" |
| Richard Losick (Harvard University)
"Searching for genes involved in asymmetric division" |
| MONDAY |
| 9:00 am - 12:30 pm | REGULATORY MECHANISMS |
| Discussion Leader: Carol Gross (University of California, San Francisco) |
| Susan Gottesman (National Cancer Institute)
"Global post-transcriptional regulation by small RNAs" |
| Maria Schumacher (Oregon Health & Science University)
"Crystal structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex" |
| Franz Narberhaus (ETH-Zurich)
"RNA thermosensors" |
| Regine Hengge-Aronis (Freie Universität Berlin)
"Signal transduction in the control of Sigma-S proteolysis in E. coli" |
| Carol Gross (UCSF)
"Sensing extracytoplasmic stress" |
| Tania Baker (Massachusetts Institute of Technology)
"Clp/Hsp100 proteins: substrate recognition and the changing bacterial proteome" |
| 4:00 pm - 6:00 pm | POSTER SESSION |
| 7:30 pm - 9:30 pm | PH EXTREMES |
| Discussion Leader: Joan Slonczewski (Kenyon College) |
| Joan Slonczewski (Kenyon College)
Microbial pH, what we know and what is next? |
| George Sachs (University of California, Los Angeles)
"Urease and acid stress in Helicobacters" |
| Conor O'Byrne (National University of Ireland-Galway)
Acetate stress in E. Coli: a problem with methionine biosynthesis? |
| Herb Arst (Imperial College School of Medicine at Hammersmith Hospital)
"How fungi cope with extremes of pH" |
| Nicole Broderick (University of Wisconsin-Madison)
"Life at the pH extremes: microbial life in caterpillar guts and acid mine drainage" |
| TUESDAY |
| 9:00 am - 12:30 pm | METALS, O2, NO |
| Discussion Leader: Jung-Hye Roe (Seoul National University) |
| Tom O'Halloran (Northwestern University)
"Metal profiling: molecular mechanisms for regulating inorganic quotas" |
| Mark Buttner (John Innes Centre)
"Sensing and responding to disulphide stress in Streptomyces" |
| Mayuree Faungthong (Cornell University)
"Sensing of peroxides by the Bacillus subtilis organic hydroperoxide resistance repressor, OhrR |
| Steve Finkel (USC)
"Multiple roles of E. Coli Dps protein during stationary phase" chromosome organization, stress protection and iron "buffering"" |
| Frederik Barras (CNRS - Marseille)
"The Suf system of E. coli: assembly or repair of iron-sulfur proteins under oxidative stress?" |
| Carl Nathan (Weill Medical College of Cornell University)
"New mechanisms of microbial defense against oxidative and nitrosative stress" |
| Ferric Fang (University of Washington School of Medicine)
"Nitrosative stress in Salmonella" |
| 4:00 pm - 6:00 pm | POSTER SESSION |
| 7:30 pm - 9:30 pm | DEVELOPMENT |
| Discussion Leader: Joanne Willey (Hofstra University) |
| Joanne Willey (Hofstra University)
Extracellular signals involved in Streptomyces coelicolor development |
| Christine Jacobs (Yale University)
"Spatial and temporal sensing by two-component proteins during the bacterial cell cycle" |
| Kit Pogliano (University of California, San Diego)
"Dynamic reorganization of the B. subtilis cell during sporulation" |
| Heidi Kaplan (University of Texas Medical School)
"Parallel pathways that sense and integrate envelope stress, starvation and cell density signals control early Myxococcus xanthus developmental gene expression" |
| Susan Golden (Texas A&M University)
"Circadian rhythms of gene expression in cyanobacteria" |
| WEDNESDAY |
| 9:00 am - 12:30 pm | HOST-PATHOGEN INTERACTIONS |
| Discussion Leader: Man-Wah Tan (Stanford University School of
Medicine) |
| Man-Wah Tan (Stanford University School of
Medicine)
Common themes in microbe-host interactions |
| Eduardo Groisman (Washington University)
"Stresses experienced by Salmonella in host and non-host environments" |
| Jeff Miller (University of California, Los Angeles)
"Parasite adaptations to dynamic hosts: Bordetella and their phage" |
| Ralph Isberg (Tufts University School of Medicine)
"Cross-talk between Legionella pneumophila and its macrophage host" |
| Olaf Schneewind (University of Chicago)
"Substrate recognition and regulation of transport by the type III machinery of pathogenic yersiniae" |
| Gail Ferguson (MIT)
"An investigation into the role of BacA in the establishment of chronic bacterial infections" |
| 4:00 pm - 6:00 pm | POSTER SESSION |
| 7:30 pm - 9:30 pm | QUORUM SENSING, BIOFILMS |
| Discussion Leader: Roberto Kolter (Harvard Medical School) |
| Steve Winans (Cornell University)
"Structural studies of a quorum sensing transcriptional regulator" |
| Bonnie Bassler (Princeton University)
"Intra- and inter-species communication in bacteria: the LuxS quorum sensing language" |
| Søren Molin (Technical University of Denmark)
"Nutritional heterogeneity in bacterial biofilms: Impacts on community organization and development" |
| THURSDAY |
| 9:00 am - 12:30 pm | ANTIBIOTIC RESISTANCE, GENOME DYNAMICS |
| Discussion Leader: Tom Dougherty (Pfizer, Inc.) |
| Tom Dougherty (Pfizer, Inc.)
The role of microbial genomics in understanding bacterial resistance |
| Richard Brennan (Oregon Health & Science University)
"Structural basis of bacterial multidrug recognition" |
| Matt Waldor (Tufts University School of Medicine)
"SOS control of conjugal gene transfer" |
| Howard Ochman (University of Arizona)
"A glimpse of bacterial genome evolution" |
| Dominique Schneider (Université Joseph Fourier)
"Genetic diversity and fixation of beneficial mutations during 10,000 generations of experimental evolution in Escherichia coli populations" |
| 4:00 pm - 6:00 pm | POSTER SESSION |
| 7:30 pm - 9:30 pm | LIFE AT THE EXTREMES, METABOLIC DIVERSITY |
| Discussion Leader: John Battista (Louisiana State University) |
| John Battista (Louisiana State University)
Metabolic diversity: adjusting our perception of what is normal |
| Karen Nelson (The Institute for Genome Research)
"Microbial genomics: a window into evolution and physiology" |
| Nancy Love (Virginia Polytechnic Institute and State University)
"In search of physiological mechanisms for activated sludge deflocculation caused by toxic chemicals" |
| Mary Lidstrom (University of Washington)
"Methylotrophy: the stress of growing on formaldehyde" |
