| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Prokaryotic Development |
| 7:30 | Discussion Chair - Dale Kaiser (Stanford University) |
| 7:45 | Jeffrey Errington (University of Oxford)
"Cell shape" |
| 8:15 | Mitchell Singer (University of California, Davis)
"Circuits in Myxococcus xanthus" |
| 8:45 | Marie Elliot (John Innes Center)
"Aerial morphogenesis in Streptomyces" |
| 9:15 | Joanne Willey (Hofstra University)
"Revealing the secrets of the Streptomyces coelicolor morphogenetic protein SapB" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:45 am | Photo |
| 9:00 am - 12:30 pm | Oxidant Stresses: How do Organisms Cope? |
| 9:00 | Discussion Chair - Chris Kaiser (Massachusetts Institute of Technology)
The
eukaryotic disulfide bond formation pathway |
| 9:30 | Michel Toledano (Laboratoire Stress Oxydants et Cancer SBGM/DBJC)
"Oxygen stress" |
| 10:00 | Matthew Wood (NIH, NICD)
"Structural basis for redox regulation of Yap1 transcription factor localization" |
| 10:15 | Coffee |
| 10:45 | Patricia Kiley (University of Wisconsin)
"Fe-S cluster assembly" |
| 11:15 | James Bardwell (University of Michigan)
"Disulfide bond formation" |
| 11:45 | Carl Bauer (Indiana University)
"Photosynthesis" |
| 12:15 | Tim Donohue (University of Wisconsin)
"Response of Rhodobacter sphaeroides to singlet oxygen stress" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Proteolysis in Development and Stress |
| 7:30 | Discussion Chair - Tania Baker (Massachusetts Institute of Technology) |
| 7:45 | Yoshinori Akiyama (Kyoto University)
"Control of envelope stress by regulated proteolysis of RseA" |
| 8:15 | Michael Ehrmann (Cardiff University)
"Regulated proteolysis by DegP and DegS" |
| 8:45 | Corinna Wilken (Institute for Molecular Pathology)
"Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease" |
| 9:00 | Christopher Hayes (Massachusetts Institute of Technology)
"Killing the Messenger: Ribosome pausing & cleavage of the A-site mRNA codon" |
| 9:15 | Donald Rowen (University of Nebraska)
"Proteolysis of the anti-sigma factor MucA by Prc induces mucoidy in Pseudomonas" |
| 9:30 | Reception |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | The Host-Pathogen Interaction: Another Face of Stress |
| 9:00 | Discussion Chair - Jorge Galan (Yale University) |
| 9:30 | Joan Mecsas (Tufts University)
"Role of Yersinia Yops in combating innate immune defenses" |
| 10:00 | Valerie Oke (University of Pittsburg)
"Roles of multiple RpoH's and GroESL's in the Rhizobium-legume symbiosis" |
| 10:15 | Coffee |
| 10:45 | Mary Beth Mudgett (Stanford University)
"Xanthomonas type III effectors mimic plant SUMO proteases during infection" |
| 11:15 | Jeffery Cox (University of California, San Francisco)
"A novel protein secretion system in Mycobacterium tuberculosis required for evasion of host defenses" |
| 11:45 | Anita Sil (University of California, San Francisco)
"Histoplasma" |
| 12:15 | Jay Mellies (Reed College)
"recA-dependent response to DNA damage induces transcription of virulence genes of EPEC" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Computational and Genomic Approaches to Signaling (I) |
| 7:30 | Discussion Chair - Uri Alon (Weizmann Institute of Science) |
| 8:00 | Michael Savageau (University of California, Davis)
"Modeling regulatory responses" |
| 8:30 | Michael Elowitz (California Institute of Technology)
"Noisy Machines: Stochasticity and variation in living cells" |
| 9:00 | Jonathan Weissman (University of California, San Francisco)
"Proteomics" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 9:45 am | Computational and Genomic Approaches to Signaling (II) |
| 9:00 | Mark Goulian (University of Pennsylvania)
"Design features of two two-component systems" |
| 9:30 | Nir Freidman (Harvard University)
"Precise temporal modulations in the SOS response to DNA damage observed in individual cells" |
| 9:45 am - 12:30 pm | Role of Small RNAs in Sensing and Regulating Stress |
| 9:45 | Discussion Chair - Susan Gottesman (National Institute of Health, National Cancer Institute) |
| 10:00 | Gisela Storz (NIH, NCI)
"Regulating E. coli gene expression with cis-encoded antisense RNAs" |
| 10:30 | Coffee |
| 11:00 | Eric Masse (Universite de Sherbrooke)
"Regulation of iron balance by a small RNA" |
| 11:30 | Tina Henkin (Ohio State University)
"Direct metabolic sensing by RNA" |
| 12:00 | Karen Wassarman (University of Wisconsin)
"6S RNA function enhances long term survival of E. coli by regulation of transcription" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:00 | Business Meeting |
| 7:30 pm - 9:30 pm | Microbial Ecology and Diversity |
| 7:30 | Discussion Chair - James Tiedje (Michigan State University)
"Environmental stress response in communities and individuals" |
| 8:00 | Dianne Newman (California Institute of Technology)
"How Bacteria Respire Minerals" |
| 8:30 | Michael Brown (Stanford)
"Inorganic polyphosphate in the origin and survival of species" |
| 9:00 | Roy Kishony (Harvard University)
"Stress-mutation interactions in Escherichia coli" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Signal Transduction Pathways in Stress Responsive Gene Expression |
| 9:00 | Discussion Chair - Regine Hengge (Freie Universität Berlin) |
| 9:15 | Ursula Jakob (University of Michigan)
"Redox Sensing" |
| 9:45 | Peter Zuber (Oregon Health Sciences University)
"Role of Spx-RNA polymerase interaction in the disulfide stress response" |
| 10:15 | Cofffee |
| 10:45 | Mark Paget (University of Sussex)
"Sensing redox imbalance in Streptomyces" |
| 11:15 | Stephanie Gon (Harvard University)
"DnaA mutants may reveal a link between replication and oxidative stress" |
| 11:30 | William Burkolder (Stanford University)
"Regulation of the Sda-dependent sporulation checkpoint in response to replication status" |
| 11:45 | Thorsten Mascher (University Göttingen Institute of Microbiology & Genetics)
"Cell envelope stress response in Bacillus subtilis: a LiaRS story" |
| 12:00 | Tracy Dalton (Emory University)
"CovS inactivates CovR and is required for growth under conditions of general stress in Streptococcus pyogenes" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Sensing Growth Stages |
| Discussion Chair - Mark Buttner (John Innes Centre) |
| Beth Lazzazera (University of California, Los Angeles)
"Coordinating biofilm formation and sporulation by Bacillus subtilis" |
| Steve Branda (Harvard University)
"Good biofilm, bad biofilm: sin in Bacillus subtilis communities" |
| Jorge Escalante-Semerena (University of Wisconsin)
"The Sir2-dependent protein acetylation/deacetylation system of bacteria" |
| Thomas Nyström (Goteborg University)
"Role of protein oxidation in the E. coli response to growth arrest" |
| Xin Jiang (University of California, San Diego)
"Zipper-like interaction between proteins in adjacent daughter cells mediates protein localization and intercellular signaling during Bacillus subtilis sporulation" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
